Clinical trials: Poor Weight Loss
Obesity, Diabetes
Semaglutide 2.4 mg in Patients With Poor Weight-loss
A double-blinded, randomised, placebo-controlled trial of semaglutide 3.0 mg/ml in patients with poor weight-loss following bariatric surgery.
- Conditions
- Obesity, Diabetes, Metabolic Syndrome
- Trial name
- BARI-STEP (NCT05073835)
- Testing
- Semaglutide 3 mg
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University College, London
Anorexia, Cachexia
Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Infliximab may improve cancer-related weight loss, lack of appetite, and fatigue.
- Conditions
- Anorexia, Cachexia, Fatigue, Lung Cancer
- Trial name
- NCT00040885
- Testing
- infliximab, docetaxel
- Where
- 188 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alliance for Clinical Trials in Oncology
PreDiabetes
The Inspiring Action to Prevent Diabetes Intervention
This research is studying how to help increase uptake of and engagement in formal Diabetes Prevention Programs to improve healthy behaviors among adults with pre diabetes to reduce risk of getting diabetes.
- Trial name
- INSPIRA (NCT06001801)
- Testing
- Diabetes Prevention Program, INSPIRA
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Michigan
Pediatric Obesity
Packaging and Disseminating the JOIN for ME Program in Low-Income Settings
One in five children in the United States have obesity, and under-served populations are differentially impacted by both obesity and its related health consequences.
- Trial name
- NCT04647760
- Testing
- JOIN for ME
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity
Research Intervention to Support Healthy Eating and Exercise
The primary aim of this study is to test the efficacy of a behavioral economics intervention for weight loss in adults from economically disadvantaged backgrounds.
- Trial name
- RISE (NCT04353258)
- Testing
- Behavioral Economics intervention (BE mHealth), Standard mHealth intervention (mHealth)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of Connecticut
Malnutrition, Child
Effectiveness of a Positive Deviance Program in Reducing Childhood Undernutrition
Globally, childhood malnutrition remains a public health concern. Malnutrition can be diverse from undernutrition to overnutrition.
- Trial name
- NCT04688515
- Testing
- Nutrition program developed using positive deviance approach
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Obesity & Overweight, Hair Loss
Scalp Hair Metabolomics in Severe Obesity
The purpose of this research study is to investigate how body weight and weight-loss surgery affect the natural chemicals found in scalp hair over time.
- Conditions
- Obesity & Overweight, Hair Loss, Metabolomics, Bariatric Surgery
- Trial name
- NCT07368842
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Pregnancy, Weight Loss
Healthy4Baby: Preventing Postpartum Weight Retention Among Low-Income, Black Women
The purpose of this study is to assess the feasibility and efficacy of an electronically-mediated, pregnancy and postpartum, behavioral intervention program, compared to usual obstetric care, on changes in weight and…
- Conditions
- Pregnancy, Weight Loss, Behavioral, Obesity
- Trial name
- NCT01530776
- Testing
- Healthy Lifestyle Group
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity, Hypertension
Evaluating a Blood Pressure Reduction and Weight Loss Program in a Low Income, Ethnically Diverse Population (The Be Fit, Be Well [BFBW] Study)
Obesity is a serious health problem that is a contributing factor for heart disease and high blood pressure. This study will evaluate a lifestyle modification program that aims to encourage weight loss and improve the health of…
- Trial name
- BFBW (NCT00661817)
- Testing
- Lifestyle Modification Program, Usual Care and Reading Materials
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Weight Loss, Diet Habit
Koa Family: California's Obesity Prevention Project
The purpose of this study is to learn if a new whole-person lifestyle program improves the health of low-income mothers.
- Conditions
- Weight Loss, Diet Habit, Physical Activity, Overweight and Obesity
- Trial name
- NCT03605888
- Testing
- Koa Family
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- University of California, Davis
Clinically Severe Obesity, Obesity Recidivism
Adding Malabsorption for Failed Gastric Bypass
The main aim of this study is to analyze and report the preliminary and intermediate term outcomes after laparoscopic revision Roux-en-Y gastric bypass surgery for weight recidivism.
- Conditions
- Clinically Severe Obesity, Obesity Recidivism, Inadequate Initial Weight Loss, Poor Weight Loss
- Trial name
- NCT01040481
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Obesity
Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos
Physician-based primary care has thus far failed to address the obesity epidemic. In this randomized clinical trial of 200 obese patients with heart disease risk factors, the investigators will evaluate the impact of nurse and…
- Trial name
- VAFO (NCT01242683)
- Testing
- Vivamos Activos Fair Oaks Program
- Where
- 4 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
PCOS, Obesity
Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin
The purpose of this study was to determine whether combined treatment with liraglutide and metformin is more effective than liraglutide or metformin as monotherapy in the treatment of obese women with polycystic ovary syndrome…
- Trial name
- NCT01911468
- Testing
- metformin, liraglutide, metformin and liraglutide
- Where
- Slovenia
- Volunteers
- 36 people
- Sponsor
- University Medical Centre Ljubljana
Obesity & Overweight
Transcutaneous Auricular Vagus Nerve Stimulation for Poor Weight-Loss Response to Lifestyle Intervention
This single-center, randomized, single-blind, sham-controlled pilot study aims to evaluate the adjunctive effect of transcutaneous auricular vagus nerve stimulation (taVNS) in overweight/obese patients who show a poor weight loss…
- Trial name
- NCT07630597
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Weight Loss, Obesity
Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery
Purpose and objective: To identify in the early post-operative period following laparoscopic Roux-en-Y gastric bypass patients likely to fail to progressively lose weight in expected fashion, and to institute intervention and…
- Trial name
- Back on Track (NCT01329692)
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Stroke, Malnutrition
Nutritional Therapy for Stroke Patients
Prospective, short-term studies in patients admitted for acute stroke have shown an increased risk of infections, bedsores, impaired functional outcome, slower rate of recovery, poorer rehabilitation potential and higher…
- Conditions
- Stroke, Malnutrition, Weight Loss, Dysphagia
- Trial name
- NCT00163007
- Testing
- Nutritional support
- Where
- Norway
- Volunteers
- 125 people
- Sponsor
- Ostfold Hospital Trust
Obesity & Overweight
Transcutaneous Auricular Vagus Nerve Stimulation for Poor Weight-Loss Response to Incretin Receptor Agonists
This is a single-center, randomized, participant-blinded, sham-controlled trial designed to evaluate the adjunctive effect of transcutaneous auricular vagus nerve stimulation (taVNS) in overweight or obese patients who show a…
- Trial name
- NCT07619989
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Obesity, Nutrition Poor
Healthy Frio: A Rural Community Partnership to Advance Latino Obesity Research
Much has been learned about the efficacy and effectiveness of comprehensive healthy lifestyle interventions to reduce obesity. Few studies have been translated into rural settings or among Latinos.
- Conditions
- Obesity, Nutrition Poor, Physical Activity, Weight Loss
- Trial name
- NCT03186885
- Testing
- Healthy Frio In-Person Family-focused Intervention, Healthy Frio Remote Technology Family-focused Intervention, Control
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Texas at Austin
Weight Loss
Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families
The purpose of this study is to compare the effect on weight and metabolic outcomes of an enhanced intervention, comprised of evidence-based financial coaching plus a lifestyle intervention vs. the lifestyle intervention alone
- Trial name
- NCT05944549
- Testing
- Financial coaching using TrustPlus, Brighter Bites, Noom
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity
Effects of Weight Loss on Vascular Function in Obese Subjects
To evaluate the effect of weight loss on vascular function in obese with poor cardiovascular health. The investigators will evaluate the effects of weight loss on total and central body adiposity, blood pressure, central…
- Trial name
- NCT04198519
- Testing
- Weight Loss
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mario Fritsch Neves