Clinical trials: Polypharmacy
Polypharmacy
Measuring the Impact of an Interdisciplinary Polypharmacy Clinic Within a Patient-centered Medical Home
Title: Measuring the impact of an interdisciplinary polypharmacy clinic within a patient-centered medical home Objectives: The primary objective of this project will be to track the types of interventions made in an…
- Trial name
- NCT02077725
- Testing
- interdisciplinary polypharmacy clinic visit
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Medication Overuse, Deprescriptions
Prescribing Outcomes of a GP-Targeted Deprescribing Educational Intervention: A Cluster Randomized Trial
Polypharmacy is a common and growing public health concern across healthcare settings worldwide and is associated with an increased risk of inappropriate prescribing and adverse drug events.
- Conditions
- Medication Overuse, Deprescriptions, Polypharmacy, Frailty Syndrome
- Trial name
- NCT06470308
- Testing
- Medication Reviews and Deprescribing
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Crete
Chronic Illness, Opioid Use
Characteristics and Clinical Implications of a Clinical Decision Support System
The investigators propose to study the feasibility, acceptability, usability and outcomes of a new clinical decision support system for clinicians of opioid therapy in the context of specialist palliative care for serious chronic…
- Conditions
- Chronic Illness, Opioid Use, Palliative Care
- Trial name
- NCT03295097
- Testing
- Clinical Decision Support System
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Hospice of Henderson County, Inc.
Prescribing Decisions, Diabetes
Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions
The goal of this pilot clinical trial is to learn if providing a clinical decision framework for managing older adults chronic conditions during hospitalization to inpatient clinicians improves clinicians' ability to…
- Conditions
- Prescribing Decisions, Diabetes, Multimorbidity, Hypertension
- Trial name
- NCT06605807
- Testing
- Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pittsburgh
Eligible Patients Are Aged 65 Years or More Admitted to One of the Five Medicines for Older People Wards, Who Have ACB Score of 3 or More
The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients
The feasibility and acceptability of a collaborative deprescribing intervention to reduce anticholinergic burden among hospitalised older patients
- Trial name
- DART (NCT07599735)
- Testing
- Patients will receive a collaborative deprescribing intervention
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Southampton
Medication Adherence, Poly Pharmacy
Itaca App vs. Usual Care for Medication Adherence in Older Adults on Polypharmacy
The goal of this clinical trial is to learn if the use of a mobile app called Itaca improves medication adherence in older adults (aged ≥65) in a home care setting.
- Conditions
- Medication Adherence, Poly Pharmacy, Chronic Disease, Older Adults (65 Years and Older)
- Trial name
- NCT07631676
- Testing
- mobile app, Usual Care Group
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Roma La Sapienza
Dose Administration Aids, Medication Adherence
Testing a Smart Medication Dispenser (Mobili®) to Help People With Chronic Conditions Take Their Medicine
Medication adherence is one of the biggest challenges faced by healthcare systems, especially among people with multiple chronic diseases who take several medications daily.
- Conditions
- Dose Administration Aids, Medication Adherence, Polypharmacy, Technology in Health
- Trial name
- MobiMAd@PT RCT (NCT07175545)
- Testing
- Independent use of the Mobili® Device by patients, overseen by pharmacists
- Where
- Portugal
- Volunteers
- 96 people
- Sponsor
- Lusofona University
Polypharmacy, General Surgery
Polypharmacy and Associated Risk Factors and Clinical Outcomes for Surgical Patients Discharged From Hospital
The World Health Organisation Patient Safety Challenge: Medication Without Harm has brought our attention to the importance of medication-related harm as a global public health issue.
- Trial name
- NCT04805151
- Testing
- No intervention
- Where
- Iceland
- Volunteers
- 56,000 people
- Sponsor
- University of Iceland
Schizophrenia
Antipsychotic Polypharmacy in Schizophrenia
The literature suggests that when a patient is prescribed more than one antipsychotic for at least 30 days, he or she is likely to continue on that combination.
- Trial name
- NCT00493233
- Testing
- 2 antipsychotic medications (combinations of olanzapine, risperidone, clozapine, seroquel, haldol, perphenazine)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre for Addiction and Mental Health
Medication Therapy Management, Medication Adherence
Polymedication-Check With Insight in Patients' Medication Organisation and Comprehension of Generics
Patients using multiple drugs including generics have found different solutions to manage their medication. During a Polymedication-Check (medication review type 2a service in community pharmacies) additional information about…
- Trial name
- NCT03321058
- Testing
- Assessment
- Where
- Switzerland
- Volunteers
- 125 people
- Sponsor
- University Hospital, Basel, Switzerland
Psychotic Disorders
A Study Based on the French National Health Insurance Database in Participants With Psychotic Disorders
The primary purpose of the study is to compare therapy with antipsychotic medication (antipsychotic monotherapy or antipsychotic combination) versus no antipsychotic medication, and antipsychotic monotherapy versus antipsychotic…
- Trial name
- NCT05633108
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 579,728 people
- Sponsor
- Eisai Co., Ltd.
Sarcopenia
(De)Prescribing in Hospitalized Sarcopenic Geriatric Patients
The goal of this clinical trial is to compare the effects of a deprescribing pharmacotherapy approach to the STOPP-START approach (usual care) in geriatric patients with sarcopenia and polypharmacy.
- Trial name
- MEDEGESARC (NCT05757765)
- Testing
- deprescribing pharmacotherapy approach (DPA), STOPP-START deprescribing approach (SSA)
- Volunteers
- 160 people
- Sponsor
- Zuyderland Medisch Centrum
Chronic Disease
Feasibility Study of the Medication Review With Follow up Service for Patients With Polypharmacy in Swiss Community Pharmacies
In Switzerland, it is estimated that 20,000 people are hospitalized each year as a result of drug related problems (DRP). Community pharmacies (CP) are well positioned to identify and manage such DRPs in a timely manner.
- Trial name
- MaJ? (NCT05348538)
- Testing
- Medication review with follow up or MaJ? for the acronym in french
- Where
- Switzerland
- Volunteers
- 162 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Diabetes Mellitus
The Rates of Overtreatment and Deintensification in Patients With Diabetes Mellitus
This study evaluates the overtreatment and deintensification rates of antidiabetic and antihypertensive medications in patients with diabetes mellitus in Turkey.
- Trial name
- NCT03503045
- Where
- Turkey (Türkiye)
- Volunteers
- 1,276 people
- Sponsor
- Gulhane School of Medicine
Dementia, Potentially Inappropriate Medication Use
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
The overarching goal of this study is to pilot an intervention in which older adults with mild cognitive impairment and dementia and the older adult's care partners are identified in primary care and provided with educational…
- Conditions
- Dementia, Potentially Inappropriate Medication Use, Mild Cognitive Impairment (MCI)
- Trial name
- e-ALIGN (NCT07454824)
- Testing
- e-ALIGN Patient-Portal Deprescribing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Comorbidity, Medication Therapy Management
Effectiveness of a Medication Wallet Card
This study evaluates whether or not the use of a medication wallet card in patients over 70 taking 5 or more medications promotes self-efficacy with regards to coping with illness, understanding medications, and staying healthy.
- Conditions
- Comorbidity, Medication Therapy Management, Polypharmacy
- Trial name
- NCT02820129
- Testing
- Medication Wallet Card, Reminder Card
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University