Clinical trials: Polyp of Colon
Colonic Neoplasms, Colonic Polyp
Effectiveness of Artificial Intelligence - Assisted Colonoscopy in Colorectal Neoplasms
The primary goal of this study is to estimate the effectiveness of a medical decision support system based on artificial intelligence in the endoscopic diagnosis of benign tumors.
- Conditions
- Colonic Neoplasms, Colonic Polyp, Diagnosis
- Trial name
- ArtInCol (NCT06469671)
- Testing
- The system based on real - time artificial intelligence - assisted for colonoscopy
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Attenuated Familial Adenomatous Polyposis, Colorectal Carcinoma
Testing Obeticholic Acid for Familial Adenomatous Polyposis
This phase IIa trial investigates if giving obeticholic acid (OCA) is safe and has a beneficial effect on the number of polyps in the small bowel and colon in patients with familial adenomatous polyposis (FAP).
- Conditions
- Attenuated Familial Adenomatous Polyposis, Colorectal Carcinoma, Duodenal Carcinoma, Familial Adenomatous Polyposis
- Trial name
- NCT05223036
- Testing
- Biopsy Procedure, Biospecimen Collection, Gastrointestinal Endoscopy
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 15 people
- Sponsor
- National Cancer Institute (NCI)
Colonic Polyp, Colonic Neoplasms
Endoscopic Surveillance in Serrated Polyposis Syndrome and Low-risk of Advanced Neoplasia
The aim of the study is to determine if Serrated Poliposis Syndrome (SPS) patients with SPS criteria, with clearing phase achieved and without any advanced lesion or less than 5 relevant lesions at last colonoscopy have the same…
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Cancer, Serrated Polyposis
- Trial name
- NCT04906343
- Testing
- Colonoscopy
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Hospital Universitario de Móstoles
Colorectal Polyp, Colorectal Adenoma
Standard Colonoscopy Versus Colonoscopy With Endocuff Vision
This study seeks to compare colonoscopy results between a standard method and one using a distal scope attachment (Endocuff Vision).
- Conditions
- Colorectal Polyp, Colorectal Adenoma, Colon Cancer
- Trial name
- NCT03361917
- Testing
- Endocuff Vision
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonic Polyp, Colorectal Polyp
COLO-DETECT: Can an Artificial Intelligence Device Increase Detection of Polyps During Colonoscopy?
COLO-DETECT is a clinical trial to evaluate whether an Artificial Intelligence device ("GI Genius", manufactured by Medtronic) can identify more polyps (pre-cancerous growths of the bowel lining) during colonoscopy (large bowel…
- Conditions
- Colonic Polyp, Colorectal Polyp, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT04723758
- Testing
- GI Genius-assisted diagnostic colonoscopy, Diagnostic Colonoscopy
- Where
- 10 sites in United Kingdom
- Volunteers
- 2,032 people
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Colorectal Cancer, Advanced Adenocarcinoma
A Multicenter Clinical Trial of Stool-based DNA Testing for Early Detection of Colon Cancer in China
According to data from Global Cancer Statistics 2018, colorectal cancer (CRC) ranks second in incidence and fifth in mortality among all cancers in China.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Hyperplastic Polyp, Colorectal Neoplasms
- Trial name
- NCT04722055
- Testing
- Multigene Methylation Detection Kit
- Where
- China
- Volunteers
- 1,273 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Adenoma Colon, Colon Polyp
COmparison of White Light and Linked COlor Imaging for Detection of RIght COlon Polyps
Comparison of the number of adenomas missed by the first exploration of the right colon by LCI (linked color imaging) or by white light during a colonoscopy, according to the order of randomization.
- Conditions
- Adenoma Colon, Colon Polyp, Colonoscopy
- Trial name
- COCORICO (NCT04112563)
- Testing
- exploration in white light (WLI), Exploration in LCI
- Where
- France
- Volunteers
- 686 people
- Sponsor
- Société Française d'Endoscopie Digestive
Colonic Polyps
Positioning During Colonoscopy
Colonoscopy is the gold standard investigation in the screening of colorectal neoplasms. The investigators hypothesise that visualisation of the colonic mucosa on extubation may be improved by changing patient position as…
- Trial name
- NCT01254435
- Testing
- Colonoscopy
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Colonic Polyps
The Efficacy and Safety of a Hybrid Hemostatic Device (ClearCoajet)
The ClearCoajet is a new hemostasis device with a hybrid function (Coagulation + Injection) and is developed to provide effective coagulation, injection, and marking around lesions without changing devices during the endoscopic…
- Trial name
- NCT05737017
- Testing
- ClearCoajet
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul St. Mary's Hospital
Adenomatous Polyposis Coli
Sirolimus and Familial Adenomatous Polyposis (FAP)
The aim of the study is to investigate the effect of sirolimus on the progression of intestinal adenomas in patients with FAP and to assess the safety of this treatment.
- Trial name
- NCT03095703
- Testing
- Sirolimus
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Adenoma Colon
Effect of Water Exchange Plus Acetic Acid Staining on the Detection of Flat Polyps During Colonoscopy
Our previous study (Am. J. Gastroenterol. 2017 04;112(4)) showed that water exchange (WE) colonoscopy was able to increase the detection of flat adenomas as well as overall ADR.
- Trial name
- NCT04464135
- Testing
- acetic acid staining, Water exchange colonoscopy
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Air Force Military Medical University, China
Colorectal Cancer, Polyps of Colon
Detection of Colorectal Cancer in Patients With a Positive Fecal Immunochemical Test Using an Electronic Nose Device (AeoNoseTM)
The present study aims to investigate the diagnostic accuracy of exhaled breath analysis with the Aeonose (the eNose Company, Zutphen, the Netherlands) to distinguish the breath of patients suspected for CRC (based on a positive…
- Trial name
- NCT03346005
- Testing
- Aeonose
- Where
- Netherlands
- Volunteers
- 3,345 people
- Sponsor
- Radboud University Medical Center
Ulcerative Colitis, Inflammatory Bowel Disease (IBD)
Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications.
- Conditions
- Ulcerative Colitis, Inflammatory Bowel Disease (IBD), Acute Severe Ulcerative Colitis
- Trial name
- COLIBRI (NCT07082231)
- Testing
- Blood sample, biopsy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Colonoscopy, Histology
In Vivo Computer-aided Prediction of Polyp Histology on White Light Colonoscopy
Our group, prior to the present study, developed a handcrafted predictive model based on the extraction of surface patterns (textons) with a diagnostic accuracy of over 90%24.
- Conditions
- Colonoscopy, Histology, Computer-aided Diagnosis, Artificial Intelligence
- Trial name
- NCT03775811
- Testing
- AUTOMATED POLYP CLASSIFICATION
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Polyps, Neoplasms
Advanced Endoscopic Imaging in Colonoscopy
The aim of the study is to evaluate the usefulness of high-tech endoscopy in clinical practice. The important elements of this evaluation are: Evaluation of the character of neoplastic lesions in the colon based on different…
- Trial name
- AEI (NCT02929381)
- Testing
- Innovative colonoscopy (Olympus CF-HQ190L, NBI + Dual Focus), Conventional colonoscopy (Olympus CF-H180DL)
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Miroslaw Szura
Adenoma, Colon Polyps
Cap Assisted Colonoscopy for the Detection of Colon Polyps
This simple technique of attaching a transparent cap to the tip of the colonoscope has been evaluated in Japan for improving the detection of polyps and cecal intubation but has not been formally evaluated in the US and other…
- Conditions
- Adenoma, Colon Polyps, Colon Cancer
- Trial name
- NCT01211132
- Testing
- Cap - Transparent retractable extension device., Standard
- Where
- United States
- Volunteers
- 462 people
- Sponsor
- American Society for Gastrointestinal Endoscopy
Colonic Polyps
UEMR vs. CEMR for Diminutive Non-pedunculated Colorectal Polyps
This clinical trial is being conducted to compare the efficacy and safety of two standard methods of polypectomy，Conventional Endoscopic Mucosal Resection（EMR）and Underwater Endoscopic Mucosal Resection（UEMR），for small colorectal…
- Trial name
- NCT03833492
- Testing
- Underwater EMR
- Where
- 3 sites in China
- Volunteers
- 130 people
- Sponsor
- Ningbo No. 1 Hospital
Colonic Polyps, Surveillance
Large Overuse of Post-polypectomy Surveillance Colonoscopy
In colorectal cancer screening era a huge burden of medical resources has been applied to surveillance. Although the adherence to post-polipectomy recommendations is a advocated as a mainstay for quality assurance colonoscopy…
- Conditions
- Colonic Polyps, Surveillance, Colonoscopy
- Trial name
- NCT01458093
- Testing
- colonoscopy
- Where
- Italy
- Volunteers
- 7,081 people
- Sponsor
- Valduce Hospital