Clinical trials: Pneumoperitoneum
Surgical View, Shoulder Tip Pain
Evaluation of Low Pressure Pneumoperitoneum in Bariatric Surgery (ELOPES Study)
This is a prospective study whereby it involves patients who are planned for bariatric surgery. In the bariatric surgery procedure, pneumoperitoneum pressure will be the experimental aspect in this study.
- Conditions
- Surgical View, Shoulder Tip Pain, Abdominal Pain
- Trial name
- NCT03179111
- Testing
- Pneumoperitoneum Pressure
- Where
- Malaysia
- Volunteers
- 94 people
- Sponsor
- Universiti Putra Malaysia
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Pneumoperitoneum, Trendelenburg Position
End-expiratory Pressure During Laparoscopic Surgery in the Trendelenburg Position by Electrical Impedance Tomography
Pneumoperitoneum (PNP) and the position of the patient required for laparoscopic surgery lead to pathophysiological changes that complicate anesthesia.
- Conditions
- Pneumoperitoneum, Trendelenburg Position, Laparoscopic Surgery
- Trial name
- CP-EIT (NCT06481124)
- Testing
- electrical impedance tomography
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Laparoscopic Surgery
The Use of Tidal Volume Challenge of Dynamic Parameters During Laparoscopic Surgery
Laparoscopy is increasingly used for major abdominal and pelvic surgery. As this approach is also recommended in elderly patients with serious comorbidities, optimal fluid therapy guidance during this procedure is important.
- Trial name
- NCT03467711
- Testing
- tidal volume challenge, volume expansion
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Hernia, Inguinal, Inguinal Hernia
Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery
The goal of this observational study is to learn how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery may affect changes in blood bicarbonate levels.
- Trial name
- TAPPHCO3 (NCT07473583)
- Testing
- Laparoscopic Inguinal Hernia Repair (TAPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Haseki Training and Research Hospital
Laparoscopy, Pneumoperitoneum
The Turbine-based Insufflator Safety and Feasibility Study
The turbine-based insufflator for minimal access surgery provides a new technological basis for minimal invasive surgery insufflation.
- Trial name
- TBI (NCT06319053)
- Testing
- Turbine-based insufflator
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Erasmus Medical Center
Atelectasis
Role of Lung Ultrasound Imaging for Intraoperative Monitoring of Atelectasis During Laparoscopic Surgery
General anesthesia results in the development of atelectasis in the dependent areas of the lungs exposing patients to an increased risk of hypoxemia.
- Trial name
- NCT01749436
- Testing
- Lung ultrasound imaging examinations
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Liver Surgery, Minimal Invasive Surgery
High Versus Low Pneumoperitoneum PressUre for Parenchymal Transection in Minimally Invasive Major Liver Surgery
Minimally invasive techniques in liver surgery gain popularity as they facilitate postoperative recovery while achieving comparable oncologic outcomes to the open approach.
- Conditions
- Liver Surgery, Minimal Invasive Surgery, Major Liver Resection
- Trial name
- PPULS (NCT06770803)
- Testing
- High Pressure Pneumoperitoneum, Low Pressure Pneumoperitoneum
- Volunteers
- 132 people
- Sponsor
- University Hospital Heidelberg
Intervention Affecting Autonomic Nervous System
Autonomic Nervous System Modulation During Laparoscopic Prostatectomy
The purpose of this study is to measure the variations of autonomic nervous system (ANS) modulation directed to the heart and vessels induced by pneumoperitoneum and steep trendelenburg position.
- Trial name
- NCT01927380
- Testing
- steep trendelenburg position with pneumoperitoneum
- Where
- Italy
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Pain, Inflammation
Evaluation of Adding Small Amounts of Oxygen to the CO2 Pneumoperitoneum Upon Pain and Inflammation
The study intends to investigate the use of a novel gaz-composition used during laparoscopy upon pain and inflammation in the post-operative period.
- Trial name
- NCT00678366
- Testing
- addition of 4% oxygen, carbon dioxde
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Esophageal Pressure, Recruitment Maneuver
Esophageal Pressure-guided Personalized Recruitment Pressure During Pneumoperitoneum in Trendelenburg Position Laparoscopy
This is a prospective, single-center, double-blind, randomized controlled trial designed to investigate the individual differences in recruitment efficacy and safety between personalized lung recruitment pressure based on…
- Trial name
- NCT07392918
- Testing
- Esophageal Pressure, Lung Recruitment Maneuver
- Volunteers
- 90 people
- Sponsor
- Ju Gao
Residual Neuromuscular Block, Cardiovascular Diseases
Effects of Low-pressure Pneumoperitoneum Associated With Deep Pipecuronium-induced Neuromuscular Blockade on Hemodynamic Parameters for High Cardiovascular Risk Patient Undergoing General Anesthesia
Deep neuromuscular block (DNMB) during laparoscopy induces less haemodynamic stress by facilitating low-pressure pneumoperitoneum.
- Conditions
- Residual Neuromuscular Block, Cardiovascular Diseases, Neuromuscular Blockade Monitoring
- Trial name
- NCT06517524
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Tamas Vegh, MD
Laparoscopic Surgery, Pneumoperitoneum
Low-pressure vs Standard-pressure in Laparoscopic Cholecystectomy
Background. Many studies have demonstrated reduced postoperative pain in patients undergoing lower pneumoperitoneum pressure level during laparoscopic cholecystectomy.
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Cholecystitis; Choledocholithiasis, Quality of Life
- Trial name
- NCT04146090
- Testing
- Low-pressure pneumoperitoneum, Standard pressure pneumoperitoneum
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Laparoscopic Nephrectomy, Cerebral Oxygen Saturation
Pneumoperitoneum and Cerebral Oxygenation
In this study, the changes in cerebral oxygen saturation due to low and high pressure pneumoperitoneum implementation were measured in patients who underwent laparoscopic nephrectomy.
- Trial name
- NCT04671121
- Testing
- Standart pressure pneumoperitoneum, Low pressure pneumoperitoneum
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ondokuz Mayıs University
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hysterectomy, Pneumoperitoneum
Effect of Lower Pneumoperitoneum Pressure During Laparoscopic and Robotic Hysterectomy
With the limited evidence that lower pneumoperitoneum pressures improve postoperative pain in laparoscopic or robotic hysterectomy for benign indications, we would like to determine if we can both further validate this idea but…
- Trial name
- NCT04125173
- Testing
- Pneumoperitoneum pressure = 15mmHg, Pneumoperitoneum pressure = 12mm Hg, Pneumoperitoneum pressure = 10mmHg
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Acute Appendicitis, Acute Appendicitis With Rupture
Modified Enhanced Recovery Program in Emergency Surgery (MERES)
Laparoscopic appendectomy (LA) is a widespread surgical procedure. Patients may develop considerable postoperative pain and dyspepsia resulting in prolong in-hospital stay.
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Acute Appendicitis With Peritonitis, Acute Appendicitis Without Peritonitis
- Trial name
- MERES (NCT03754777)
- Testing
- Laparoscopic appendectomy
- Where
- Russia
- Volunteers
- 122 people
- Sponsor
- Pirogov Russian National Research Medical University
Free Air in Abdomen
Point of Care Ultrasound for Diagnosis of Abdominal Free Air
This study evaluates the ability of ultrasound to identify intraperitoneal free air. The study will consist of blinded review of abdominal ultrasound images of patients before and after laparoscopic surgery, a procedure which…
- Trial name
- NCT03719872
- Testing
- Pre-Operative Transabdominal Ultrasound, Post-Operative Transabdominal Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Blehar
Robot Assisted Laparoscopic Prostatectomy
Comparison of Volume Controlled Ventilation With 1:1 Inspiratory to Expiratory Ratio and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum
The purpose of this study is to compare the 1: 1 I: E ratio VCV and the autoflow VCV in patients undergoing robot assisted laparoscopic prostatectomy
- Trial name
- NCT03202953
- Testing
- ventilation strategy 1, ventilation strategy 2
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Yonsei University
Intracranial Pressure
The Effect of Pneumoperitoneum on Intracranial Pressure in Pediatric Laparoscopic Surgery: Ultrasonographic Measurement of Optic Nerve Sheath Diameter
The pneumoperitoneum during laparoscopic surgery in pediatrics has the potential to cause an increase of intracranial pressure (ICP).
- Trial name
- NCT01840267
- Testing
- ultrasonographic measurement of optic nerve sheath diameter
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Yonsei University