Clinical trials: Placenta Accreta Spectrum
Placenta Accreta
Placenta Accreta Spectrum Disorder Conservative Managment Versus Hysterectomy Prospective Analysis
The aim of this study is to identify risk factors associated with performing cesarean hysterectomy versus conservative management in patients with placenta accreta spectrum (PAS).
- Trial name
- NCT06105034
- Testing
- interventional techniques, the severity of placental invasion, and various placental positions and suture techniques
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Nourhan Elsadany
Placenta Accreta, Third Trimester
A Serum Galectin-3 Levels in Placenta Accreta Spectrum Pregnancies
Placenta Accreta Spectrum (PAS) represents a significant cause of maternal morbidity and mortality, causing complications that surpass those posed by most routine obstetric issues.
- Trial name
- NCT05945446
- Testing
- Galectin 3
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Placenta Accreta Spectrum
Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and…
- Trial name
- NCT05510076
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Placenta Accreta
Placenta Accreta Spectrum Disorders: A. Chohan Continuous Squeezing Suture (ACCSS)
Placenta Accreta Spectrum (PAS) disorders are rising in incidence due to increased rate of repeat caesarean sections. Peripartum hysterectomy remains the only definitive treatment of massive postpartum haemorrhage related to this…
- Trial name
- ACCSS (NCT05070689)
- Testing
- ACCSS
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Sharif Medical Research Center
Placenta Accreta
MRI for the Diagnosis of Placenta Accreta Spectrum
Placenta Accreta Spectrum (PAS) is a disease associated with abnormal placental adhesion and invasion. In recent years, the incidence of PAS has increased significantly, which can cause massive postpartum hemorrhage…
- Trial name
- NCT04151979
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Placenta Accreta Spectrum
Conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique With or Without Hayman Sutures
This study evaluates whether adding Hayman sutures in the conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique reduces intraoperative blood loss and improves outcomes
- Trial name
- NCT07519993
- Testing
- Kasr Al-Ainy Technique Alone, Kasr Al-Ainy Technique + Hayman Sutures
- Volunteers
- 48 people
- Sponsor
- Cairo University
Placenta Accreta Spectrum, Abnormal Placentation
Effect of Methylene Blue Bladder Instillation on Urinary Tract Injuries During Cesarean Hysterectomy for Placenta Accreta Spectrum
This prospective cohort study aims to evaluate whether preoperative bladder filling with methylene blue dye can reduce the incidence of urinary tract injuries during cesarean hysterectomy in patients diagnosed with placenta…
- Conditions
- Placenta Accreta Spectrum, Abnormal Placentation, Cesarean Hysterectomy, Urinary Tract Injury
- Trial name
- NCT07129135
- Testing
- The bladder was filled with 300 ml diluted methylene blue (in normal saline) via Foley's catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Usama Ahmed Elsaeed Salem, MD
Placenta Previa, Placenta Accreta Spectrum
Planned Delivery at 37 Versus 36 Weeks in Pregnancies With Placenta Previaand Accreta
Current clinical practice guidelines recommend planned cesarean delivery(CD) at 34-37 weeks of gestation in pregnant women with placenta previa and accreta.
- Conditions
- Placenta Previa, Placenta Accreta Spectrum, Antepartum Bleeding, Emergency Cesarean Section
- Trial name
- NCT07025954
- Testing
- Cesarean delivery
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Placenta Accreta Spectrum
Accuracy of Placenta Accreta Index in Diagnosing Placenta Accreta Spectrum
The placenta accreta spectrum (PAS) which includes accreta, increta, and percreta represents a significant obstetric challenge. PAS complicates as many as 1 per 500 pregnancies and this risk is increased with prior cesarean…
- Trial name
- NCT04314791
- Testing
- Ultrasound evaluation, with grayscale and color Doppler imaging
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Hatem AbuHashim
Placenta Accreta, Third Trimester
Relationship Between Maternal Soluble Trigger Receptor Expressed on Myeloid Cells-1 (sTREM-1) and Placenta Accreta Spectrum
We planed to evaluate soluble the triggering receptors expressed on myeloid cell-1 (s TREM-1) levels in serum of pregnant women diagnosed with placenta accreta spectrum and compare it with healthy pregnant women's s TREM-1 serum…
- Trial name
- NCT05376410
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Placenta Accreta Spectrum, Placenta Previa
Hematological and Coagulation Markers in Predicting Placenta Accreta Spectrum in Placenta Previa
Placenta accreta spectrum (PAS) is a serious pregnancy complication where the placenta attaches too deeply into the wall of the uterus.
- Trial name
- NCT07826247
- Volunteers
- 130 people
- Sponsor
- Assiut University
Placenta Accreta
Simplified Conservative Measures in Managing Morbidly Adherent Placenta in Beni-Suef University
To evaluate the efficacy of modified uterine artery ligation and myometrial compression as a conservative measure in improving the prognosis of the morbidly adherent placenta.
- Trial name
- NCT06465836
- Testing
- O, lreay suture, modified O, lreay suture
- Where
- Egypt
- Volunteers
- 172 people
- Sponsor
- Nesreen Abdel Fattah Abdullah Shehata
Placenta Accrete Spectrum
The Accuracy Of 3D Color Ultrasonography for Detecting the Degree of Placenta Accreta Spectrum Invasion
To evaluate the correlation between preoperative ultrasound imaging findings by 3D Color Doppler Ultrasound and the intraoperative severity of Placenta Accreta Spectrum (PAS) disorders, in order to assess the diagnostic accuracy…
- Trial name
- NCT07250412
- Testing
- Cesarian section
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Placenta Accreta, Placenta Diseases
Plasma Concentration of Biological Markers in Placenta Accreta Spectrum
The purpose of this exploratory study is to determine how well maternal serum biomarkers and placental micro-particles (MP) correlate with placenta accreta spectrum (PAS) at the time of cesarean delivery in women with suspected…
- Trial name
- NCT04525534
- Testing
- There is no other intervention, only clinical treatment.
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Placenta Accreta Spectrum
New Conservative Technique for Placenta Accreta Spectrum
participants diagnosed as placenta accreta spectrum were subjected to cesarean delivery. Investigators manually detected a plan of cleavage through which the placenta was separated followed by closure of defective placental bed.
- Trial name
- percreta (NCT04427592)
- Testing
- ultrasound, closure of uterine wall defect
- Where
- Egypt
- Volunteers
- 159 people
- Sponsor
- Alexandria University
Placenta Accreta
Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta Spectrum
This study evaluates the clinical implementation of intra-operative topographic classification system for PAS. In addition to a standard of care risk stratification prenatal ultrasound for patients with a risk of PAS, this study…
- Trial name
- NCT07283042
- Testing
- Total Hysterectomy, Modified subtotal hysterectomy, One-Step Conservative Surgery
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Placenta Accreta
Placenta Accreta Spectrum Protocol
Aim of this project is to study diagnosis and management approaches of PAS and to assess safety and efficacy of different conservative approaches compared to planned hysterectomy.
- Trial name
- NCT04384510
- Testing
- Planned Cesarean hysterectomy, Conservative management
- Where
- Egypt
- Volunteers
- 1,500 people
- Sponsor
- Assiut University
Placenta Accreta
Evaluation of Planned Conservative Surgical Management of Placenta Accreta Spectrum in Women's Health Center, Assiut University Hospital
In recent years, with the application of an abdominal artery balloon and the improvement of surgical techniques, efforts are made to preserve the uterus for patients PAS.
- Trial name
- NCT06712576
- Volunteers
- 150 people
- Sponsor
- Assiut University
Placenta Accreta Spectrum
Diagnostic Trial of a Vision Transformer-Based Ultrasound AI Model for Placenta Accreta Spectrum
This study develops an end-to-end Vision Transformer (ViT)-based artificial intelligence system for ultrasound-based diagnosis of placenta accreta spectrum (PAS), aiming to improve the accuracy and efficiency of prenatal…
- Trial name
- NCT07643090
- Testing
- Vision Transformer-Based End-to-End Ultrasound Artificial Intelligence Model
- Where
- China
- Volunteers
- 561 people
- Sponsor
- FANG HE
Placenta Accreta Spectrum
Spinal Versus General Anesthesia in Pregnancies With Placenta Accreta Spectrum: A Retrospective Comparative Study
Placenta accreta spectrum (PAS) is a serious pregnancy complication in which the placenta grows abnormally into the uterine wall.
- Trial name
- SAGA-PAS (NCT07406841)
- Testing
- spinal anesthesia, General Anesthesia
- Volunteers
- 50 people
- Sponsor
- Gaziantep City Hospital