Clinical trials: Physiological Responses
Physiological Stress Responses to Standardises Stress Situations, Psychological Responses to Standardised Stress Situations
Effects of Contact to Dogs During Stressful Situations
The investigators will conduct an experimental study comparing responses of healthy participants in two test situations where they are subjected to mild stress.
- Conditions
- Physiological Stress Responses to Standardises Stress Situations, Psychological Responses to Standardised Stress Situations, Behavioural Responses to Standardised Stress Situations
- Trial name
- NCT04866173
- Testing
- Dog, No Dog
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Metabolic Regulation, Energy Expenditure
Effects of Intermittent Running on Metabolic Health
The purpose of this study is to investigate the suitability of intermittent exercise of long and short intervals at lower intensities than HIIE on energy expenditure during and post-exercise compared to MICE, as well as determine…
- Trial name
- NCT06962605
- Testing
- Moderate-intensity continuous running (MICE: 60% V̇O2max), 5-minute interval running (5MIN), 2-minute interval running (2MIN)
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Physiological Response to Exercise, Perception of Exercise Difficulty
Perception of Physical Exertion in Healthy Weight and Obese Adolescents
Little is known regarding the relationship between perceived and physiological exertion in adolescents. The purpose of this study is to investigate the association between physiological and perceptual markers of effort during…
- Trial name
- NCT01695785
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Sleep Deprivation
The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise
Sleep deprivation has been found to impact exercise performance. The effects of both partial (several hours) and full (24+ hours) sleep deprivation on exercise performance has shown effects on rating of perceived exertion, rate…
- Trial name
- NCT05313932
- Testing
- Sleep deprivation
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Response to Severe Stress
Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School
The objective of the proposed research is to determine if tyrosine, an amino acid found in protein-containing foods, will mitigate the cognitive deficits and adverse effects on behavior and mood produced by exposure to military…
- Trial name
- NCT01823276
- Testing
- Tyrosine-Containing Bar
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Hypogonadism
Oral Testosterone for the Treatment of Hypogonadism in Males
Low testosterone is a condition that occurs when the body is unable to produce sufficient quantities of testosterone. The medical name for low testosterone is hypogonadism. Hypogonadism can be caused by many factors.
- Trial name
- NCT02222558
- Testing
- TSX-002
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- TesoRx Pharma, LLC
Physiological Stress
Impact of Supplements on Stress Markers
The goal of this clinical trial is to examine the effects of caffeine, theanine and tyrosine ingestion on markers of stress in healthy college aged individuals that are exposed to a mental stress task.
- Trial name
- NCT05592561
- Testing
- mental stress task
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Texas State University
Stroke
Physiological Responses During Overground Gait Training With a Wearable Exoskeleton After Stroke
To investigate the acute physiological responses during 20-minute overground gait training with a wearable exoskeleton in persons after stroke
- Trial name
- NCT03653780
- Testing
- Ekso GT
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Vrije Universiteit Brussel
GERD
Correlates of GERD Symptom Severity
This is a pilot study measuring physiologic and behavioral correlates of symptom severity in adult patients with gastroesophageal reflux disease (GERD).
- Trial name
- NCT03020550
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Aging
Physiological Responses to a Prolonged Cycling Expedition in Older Men
The aim of this study was to test the physiological response to a 2800 km cycling expedition, from Copenhagen, Denmark to Nordkapp, Norway, in a group of older male recreational cyclists.
- Trial name
- NCT02353624
- Testing
- Cycling
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Vaccine Reaction
(VIII): The Eight Study and Immunologic Response Sub-study
The study's objective is to test the hypothesis that immune system activation and subsequent systemic inflammation can be detected through continuously tracking multiple bio signals including physiologic variables (ECG, skin…
- Trial name
- NCT05237024
- Where
- 2 sites in United States, Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- physIQ, Inc.
Pregnancy, Stress, Psychological
Happy Mommy! Happy Baby! Study
The purpose of this study is to determine how difficult life-events that women experienced during their childhood might affect their babies.
- Conditions
- Pregnancy, Stress, Psychological, Stress, Physiological, Maternal-fetal Relations
- Trial name
- FAP (NCT01700374)
- Where
- 4 sites in United States
- Volunteers
- 1,506 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Food Preferences, Appetitive Behavior
The Impact of the Physiological Response to Sugar on Brain Activity and Behavior
The goal of this pilot study is to test the feasibility of assessing how biological factors and chemical properties of sugars may influence metabolism and food reward in humans.
- Trial name
- NCT06015490
- Testing
- Sucrose drink, Glucose drink, Fructose drink
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Gastric Emptying, Diabetes Mellitus
The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.
The purpose of this study is to determine whether 3 g cinnamon was sufficient to delay the gastric emptying rate of a high-fat solid meal and subsequently reduce postprandial blood glucose and lipid responses, oxidative stress…
- Trial name
- CinnGastEmpt (NCT01350284)
- Testing
- Cinnamon
- Where
- Ireland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Bradycardia
Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response
This is a randomized, prospective, single-blinded, multi-center study involving approximately 1500 patients at 100 centers. The purpose of this study is to demonstrate the effectiveness of Closed Loop Stimulation (CLS) rate…
- Trial name
- CLEAR (NCT00355797)
- Testing
- Closed Loop Stimulation (CLS), Standard Rate Adaptive (R) Technology, Non-rate adaptive (DDD) pacing
- Where
- 99 sites in United States
- Volunteers
- 1,491 people
- Sponsor
- Biotronik, Inc.
Healthy
Physiological Response to Salbutamol and Exercise
The scope of the study is to investigate the physiological response to salbutamol and exercise. A particular focus is on the metabolic response and amine metabolism.
- Trial name
- NCT03902106
- Testing
- salbutamol, exercise
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cytokine Release Syndrome, Neoplasms
Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event
Background: Drugs or cell therapies to treat cancer can sometimes cause cytokine release syndrome (CRS). That is, the body makes too many cytokines after treatment. Cytokines are proteins that play a role in the immune system.
- Conditions
- Cytokine Release Syndrome, Neoplasms, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Trial name
- NCT07499128
- Testing
- TempTraq, VitalTraq
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- National Cancer Institute (NCI)
Healthy
A Phase 1 Study of FZ008-145 in Healthy Subjects.
The study will be conducted in 5 parts: Part A and Part B (single ascending dose [SAD] in solution formulation and tablet respectively), Part D and Part D2 (cold pressor test [CPT] to evaluate pain tolerance following single…
- Trial name
- NCT06685809
- Testing
- FZ008-145 solution, FZ008-145 Tablet
- Where
- Australia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Guangzhou Fermion Technology Co., LTD
Healthy
Brain Receptors in Sympathetic Nervous System Regulation
The purpose of this study is to investigate the role of brain receptors called alpha2-adrenoreceptors in regulating the sympathetic nervous system, which maintains the supply of blood and fuel to the body's organs in times of…
- Trial name
- NCT00029627
- Testing
- Yohimbine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)