Clinical trials: Physical Illness
Simulation of Physical Illness, Nurse's Role
Teaching the Social Determinants of Health to Nursing Students With Simulation
The goal of this intervention study is to compare two different simulation modalities (standardized patient and manikin-based) in nursing student education.
- Trial name
- NCT05685082
- Testing
- Standardized patient simulation, Manikin-based simulation
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
Acute Respiratory Failure
Effect Of Acute Inflammatory Mediators On Functional Limitations In Patients With Acute Respiratory Failure
This is a randomized, controlled, pilot study of two separate Cohorts of patients from the intensive care unit. Cohort I will enroll 50 patients and randomize to receive one physical therapy session per day or receive usual ICU…
- Trial name
- NCT01707303
- Testing
- Early ICU rehabilitation strategies, Usual Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University
Critical Illness Myopathy
NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness
The goal of this clinical trial is to study whether physical therapy can reduce NLRP3 inflammasome activation and muscle atrophy in patients with critical illness myopathy (CIM).
- Trial name
- PT-NLRP3-CIM (NCT07017517)
- Testing
- Motomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy
- Where
- 3 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Nursing Education, Simulation of Physical Illness
Moulage Technique in Child Abuse Recognition
Early recognition of physical abuse in children is essential for ensuring child safety and preventing further harm. However, distinguishing abuse-related injuries from accidental findings can be challenging, especially for…
- Conditions
- Nursing Education, Simulation of Physical Illness, Child Physical Abuse, Suspected, Sequela
- Trial name
- Moulage (NCT07509723)
- Testing
- Moulage Technique Group, movie group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlas University
Post-Intensive Care Syndrome (PICS)
Long-Term Outcomes and Post-Intensive Care Syndrome: Investigating the Associations Between Metabolic Signatures and Physical Functioning in Critically Ill Patients
Despite being young, healthy, and physically fit, some intensive care unit (ICU) patients experience significantly worse functional recovery after critical illness than older patients with multiple comorbidities although a poor…
- Trial name
- TOPICS (NCT07170527)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- ARH van Zanten, MD PhD
Autism Spectrum Disorder (ASD), Autism
Judo Training for People With Autism Spectrum Disorder, Physical Fitness and Psychological Indicators
Physical fitness and psychological indicators are key factors in healthy development. Individuals with autism spectrum disorder (ASD) tend to have lower levels of physical fitness and mental health than their neurotypical peers.
- Trial name
- JUDOASD/PA/PSY (NCT07419919)
- Testing
- Judo training for people with ASD - training in integration groups with non-ASD people
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Hematological Diseases, Critical Illness
Assessment of Admission to the ICU of Onco-hematological Patients.
Multicenter, observational and prospective study.
- Trial name
- NCT06113601
- Testing
- There is no intervention.
- Volunteers
- 800 people
- Sponsor
- University Hospital A Coruña
Insomnia
A Phase III Study of Eszopiclone in Patients With Insomnia (Study SEP 190-150)
The purpose of this study is to evaluate the long-term safety of eszopiclone (2, 3 mg) in non-elderly patients with insomnia and eszopiclone (1, 2 mg) in elderly patients with insomnia.
- Trial name
- NCT00770692
- Testing
- Eszopiclone 1 mg- Elderly, Eszopiclone 2 mg- Elderly, Eszopiclone 3 mg- Non-elderly
- Where
- 34 sites in Japan
- Volunteers
- 369 people
- Sponsor
- Eisai Co., Ltd.
Inflammatory Bowel Diseases, Maladaptive Behavior Associated With Physical Illness
TMS in Inflammatory Bowel Disease
Transcranial magnetic stimulation (rTMS) has demonstrated diagnostic and therapeutic potential for a number of conditions and is an approved treatment for depression.
- Trial name
- NCT04956159
- Testing
- iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Cybersickness, Motion Sickness
Gaze Stabilization vs Oculomotor Exercises on Cybersickness in Computer Users
Many people who use computers for long hours experience "cybersickness" (dizziness, nausea, blurred vision) because their eyes see movement on the screen but their body feels still.
- Conditions
- Cybersickness, Motion Sickness, Vestibular Diseases
- Trial name
- GAZE-CS (NCT07616596)
- Testing
- Gaze Stabilization Exercises, Oculomotor Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Faisalabad
Weakness Acquired in the ICU, Muscle Wasting
Muscle and Subcutaneous Tissue Variation by Ultrasound and Impedance Linked to Fluid Balance in ICU Patients
This cross-sectional study aims to investigate the relationship between variations in muscle thickness and subcutaneous tissue, measured by ultrasound, and fluid compartments, evaluated using bioelectrical impedance analysis…
- Conditions
- Weakness Acquired in the ICU, Muscle Wasting, Edema, Fluid Overload
- Trial name
- NCT06697470
- Testing
- Ultrasound and Bioelectrical Impedance Analysis for Muscle Thickness and Fluid Balance Assessment Translation
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Dr F Duprez
Acute Critical Illnesses in Emergency Settings, Process Optimization of Early Warning &Amp; Assessment for At-risk Emergency Patients
Early Warning Score Combined With Bedside Assessments: Accelerating Emergency Care To Improve Prognosis
Brief Summary This study, sponsored by the National Natural Science Foundation of China and conducted at the Emergency Department (ED) of Jiangnan University Affiliated Hospital, aims to optimize emergency care for critically ill…
- Trial name
- EWS-BA (NCT07249151)
- Testing
- Optimized ED Bedside Nursing Protocol
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Jun Liu
Injuries, Illnesses Systemic
Loads, Injuries and Illnesses Among Elite Handball Players
Primary goal of the research is to determine whether injury/illness occurrence is influenced by the academic, training and competition loads, as well as the overall load (sum of academic/work, training and competition loads) in…
- Conditions
- Injuries, Illnesses Systemic, Illness, Chronic, Illnesses, Occupational
- Trial name
- PPDC-2022 (NCT05471297)
- Testing
- There is no intervention
- Where
- 2 sites in Slovenia
- Volunteers
- 189 people
- Sponsor
- University of Ljubljana
Acute Illness
Evaluation of the Basic Assessment of Severity of Illness in Children (BASIC) Scale
The purpose of this study is to assess whether the BASIC Scale--a simple, non-invasive clinical triage protocol--predicts severe illness, hospitalization or death among children under age five presenting for acute care in a rural…
- Trial name
- NCT01068574
- Testing
- BASIC Score (Observational)
- Where
- Rwanda
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Childhood Illness
Community-Integrated Management of Childhood Illness (IMCI) Programme Evaluation
The proposed four-year randomized study will attempt to test the hypothesis that community-based child health interventions in conjunction with facility-based IMCI will improve child care practices, nutritional status and child…
- Trial name
- NCT00979797
- Testing
- Community-based interventions to promote maternal and child health
- Where
- Bangladesh
- Volunteers
- 140,000 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Critical Illness
The Effect of Exercise Dosage on Physical Function, Cognition and Disability Following Critical Illness
Survival following a critical illness continues to improve with ongoing developments in medical management, however evidence shows that this patient group is at a high risk of suffering long term disability.
- Trial name
- PREDICTABLE (NCT03413189)
- Testing
- Review of medical records, Assessment of physical and cognitive function, Interview of patients, carers and/or family members
- Where
- 3 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Sepsis, Critical Illness
Assessment of the Anti-inflammatory Effect of Heparin Infusion Versus Subcutaneous Injection in Septic Patients
Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep venous thrombosis (DVT), is a common and severe complication of critical illness.
- Trial name
- NCT04313790
- Testing
- Heparin Infusion, subcutaneous heparin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
ICU Acquired Weakness, Sepsis
ICU Combined Assessment of Cardio-Respiratory Exercise
This study aims to investigate how sepsis and critical illness can impair the cardiovascular system and microcirculation in intensive care unit (ICU) patients, which can lead to long-lasting muscle weakness/dysfunction or…
- Conditions
- ICU Acquired Weakness, Sepsis, Shock, Critical Illness
- Trial name
- ICU-CARE (NCT06193980)
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Mental Disorders
Impact of Joint Crisis Plan
For some patients in department psychiatric, isolation measures are put in place. But the measures is not pleasant for the patient or for the care team.
- Trial name
- PLANCO-ISO (NCT03984682)
- Testing
- Joint Crisis Plan
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Empirical Antimicrobial Therapy, Critically Ill
Empirical Meropenem Dosing in Critically Ill Patients: Early Assessment of Plasma Exposure and Minimum Inhibitory Concentration Targets
The goal of this prospective cohort study is to characterize meropenem exposure in critically ill adult patients receiving empiric antibiotic treatment in the intensive care unit (ICU).
- Conditions
- Empirical Antimicrobial Therapy, Critically Ill, Meropenem, Pharmacokinetics and Pharmacodynamics
- Trial name
- NCT07681544
- Testing
- Blood extraction
- Where
- Argentina
- Volunteers
- 26 people
- Sponsor
- Hospital Italiano de Buenos Aires