Clinical trials: Phrenic Nerve
Neuromodulation, Phrenic Nerve Stimulation
Randomized Study of the pdSTIM™ System in Failure to Wean Mechanically Ventilated Patients
This prospective, multi-center, randomized, controlled clinical trial is being conducted to evaluate the safety and efficacy of the pdSTIM System to facilitate weaning from mechanical ventilation through phrenic nerve…
- Conditions
- Neuromodulation, Phrenic Nerve Stimulation, Ventilator Induced Diaphragm Dysfunction, Mechanical Ventilation Weaning
- Trial name
- ReInvigorate (NCT05998018)
- Testing
- pdSTIM System Therapy, Conventional Medical Management
- Where
- 16 sites in United States
- Volunteers
- 32 people
- Sponsor
- Stimdia Medical Inc.
Pectus Excavatum, Cryo Analgesia
Phrenic Infiltration as Cryoanalgesia Adjuvant for Early Postoperative Pain Following the Nuss Procedure
The goal of this observational ambispective study is to compare the effectiveness of two pain management strategies in pediatric patients undergoing the Nuss procedure for pectus excavatum.
- Conditions
- Pectus Excavatum, Cryo Analgesia, Phrenic Nerve-related Diaphragmatic Impairment
- Trial name
- PHABULA (NCT07290582)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Papa Giovanni XXIII Hospital
We Evaluated CT-guided Localization of the Right Phrenic Nerve to Enhance Safety in Transcatheter Ablation
Right Phrenic Nerve Localization on CT for Ablation
The anatomical location of the right phrenic nerve (RPN) in close proximity to the right pulmonary veins has become a critical consideration for electrophysiologists performing pulmonary vein isolation, the cornerstone treatment…
- Trial name
- NCT07330791
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Centro Medico Teknon
Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block
Comparison of the Effects of Interscalene Block and Superior Trunk Block on Pulmonary Functions
The interscalene block (ISB) is one of the peripheral nerve blocks providing surgical anesthesia and postoperative analgesia in shoulder arthroscopy, eliminating the need for general anesthesia.
- Conditions
- Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block, Phrenic Nerve Paralysis
- Trial name
- NCT06703281
- Testing
- Interscalene Nerve Block, Superior trunk block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Gazi University
Prolonged Air Leak, Phrenic Nerve
Postoperative Effects of Intraoperative Temporary Phrenic Nerve Paralysis in Lung Resection Surgery
This prospective clinical study aimed to evaluate the postoperative effects of temporary phrenic nerve paralysis induced by intraoperative phrenic nerve crush during lung resection surgery.
- Conditions
- Prolonged Air Leak, Phrenic Nerve, EMG
- Trial name
- PNCrush (NCT07259031)
- Testing
- İntraoperative phrenic nerve compression
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ferdane Melike Duran
Atrial Fibrillation (AF), Phrenic Nerve-related Diaphragmatic Impairment
Diaphragmatic Evaluation by Fluoroscopy to Identify Phrenic Nerve Dysfunction Related to Electroporation
This study aims to better understand the potential side effects of a heart treatment called PFA (Pulsed Field Ablation), used to treat an arrhythmia known as atrial fibrillation.
- Trial name
- Define-PFA (NCT07127900)
- Sponsor
- Laurent Macle
Neurosurgery, Phrenic Nerve Stimulation
Intraoperative Diaphragmatic Neuromodulation
This prospective, single-center, randomized controlled clinical trial aims to investigate the impact of intraoperative phrenic nerve stimulation (i.e., diaphragmatic neuromodulation) on postoperative complications in…
- Conditions
- Neurosurgery, Phrenic Nerve Stimulation, Postoperative Delirium
- Trial name
- NCT06518707
- Testing
- Phrenic nerve stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Sanbo Brain Hospital
Phrenic Nerve, Electrical Stimulation
Repetitive Phrenic Nerve Stimulation in Critically Ill Patients Under Mechanical Ventilation
Subjects: Patients aged 19 and older who are currently in the ICU and undergoing invasive mechanical ventilation. Methods: The study involves performing non-invasive repetitive phrenic nerve stimulation in ICU patients on…
- Trial name
- NCT06491511
- Testing
- Transcutaneous, repetitive phrenic nerve electrical stimulation
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Ventilator Lung, Ventilator-Induced Lung Injury
Phrenic Identification in the ICU
This will be a prospective observational study where the investigator will scan patients' necks with an ultrasound and look for anatomical landmarks that may help identify the phrenic nerve.
- Conditions
- Ventilator Lung, Ventilator-Induced Lung Injury, Diaphragm Disease, Phrenic Nerve
- Trial name
- NCT05875883
- Testing
- Neck ultrasound
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Unity Health Toronto
Phrenic Nerve Injury
Modified Diaphragmatic Plication Rectifies Dyspnea
Traditional diaphragmatic plication (DP) surgery is employed to ameliorate respiratory function in patients with diaphragmatic paralysis, which is rather complicated. This study introduces a modified method of DP.
- Trial name
- NCT06775873
- Testing
- Modified diaphragmatic plication
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji University
Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block
Combined Anterior Suprascapular Nerve Block and Superficial Cervical Plexus Block In Shoulder Arthroplasty Surgery
The suprascapular nerve, originating from the C5 trunk, provides innervation to the acromioclavicular and glenohumeral joints. The supraclavicular nerve, a branch of the cervical plexus, contributes to the sensory innervation of…
- Conditions
- Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block, Superficial Cervical Plexus Block, Phrenic Nerve Paralysis
- Trial name
- NCT06146179
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Istanbul Medeniyet University
Diaphragms, Phrenic Nerves
Electrical Phrenic Nerve Stimulation in Patients With VIDD
This study aims to examine efficacy of transcutaneous electrical phrenic nerve stimulation (TEPNS) in ventilator-induced diaphragmatic dysfunction (VIDD).
- Trial name
- NCT06436950
- Testing
- transcutaneous electrical phrenic nerve stimulation (TEPNS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Weaning Failure, Central Respiratory Depression
Exploration of Mechanisms for Weaning Failure
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline…
- Conditions
- Weaning Failure, Central Respiratory Depression, Diaphragm Injury, Phrenic Nerve Disorder
- Trial name
- NCT06424314
- Testing
- Monitoring of respiratory mechanics parameters
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Electrical Stimulation, Phrenic Nerve
Transcutaneous Repetitive Phrenic Nerve Stimulation in Healthy Adults
The goal of this observational study is to characterize the standardized stimulation parameter for noninvasive, transcutaneous, repetitive phrenic nerve electrical stimulation.
- Trial name
- NCT05879939
- Testing
- Transcutaneous, repetitive phrenic nerve electrical stimulation
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure
A Chart Review to Evaluate the Safety and Efficacy of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis
A retrospective chart review to evaluate the safety and efficacy of phrenic nerve reconstruction for diaphragmatic paralysis.
- Conditions
- Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure, Breath Shortness, Diaphragmatic Paralysis
- Trial name
- NCT06257589
- Where
- 2 sites in United States
- Volunteers
- 700 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Phrenic Nerve Paralysis
Incidence of Hemidiaphragmatic Palsy After Interscalene Block
Primary objective of this study is to find out the incidence of hemi-diaphragmatic palsy associated with interscalene block done under ultrasound guidance.
- Trial name
- NCT01784601
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Phrenic Nerve Paralysis, Diaphragm Sellae Meningioma
Comparison of Different Approaches for Supraclavicular Block and Their Effects on Diaphragm Muscle Function
Brachial plexus blocks used for anesthesia in upper extremity operations can be performed with interscalene, axillary, supraclavicular and infraclavicular approaches.
- Conditions
- Phrenic Nerve Paralysis, Diaphragm Sellae Meningioma, Complications, Respiratory Complication
- Trial name
- NCT04756050
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Prilocaine HCl % 2 injectable solution, adrenaline amp 0.5mg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Pulmonary Function Test, Phrenic Nerve Irritation
Physical Therapy on Phrenic Nerve Function
This study was conducted to investigate the effects of a designed physical therapy program on respiratory function and phrenic nerve activity in cervical disc compression.
- Conditions
- Pulmonary Function Test, Phrenic Nerve Irritation, Cervical Disc Lesion
- Trial name
- NCT05817565
- Testing
- Ultrasound (Phyaction 190 I); with a frequency of 3 MHz was used
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Shoulder Pain, Phrenic Nerve Paralysis
Upper Trunk Block Versus Costoclavicular Block For Arthroscopic Shoulder Surgery
Interscalene brachial plexus block is known as the gold standard for analgesia after shoulder surgery, but limits the use of ipsilateral phrenic nerve paralysis.
- Trial name
- NCT04194385
- Testing
- Upper trunk block, Costoclavicular block, Diaphragmatic function assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Atrial Fibrillation, Phrenic Nerve Paralysis
Ultrasonography Evaluation of Diaphragm Kinetics in Patients Undergoing Atrial Fibrillation Ablation With Cryoballoon
The purpose of this study to assess the diaphragm kinetics with Tissue Doppler Imaging in patients undergoing atrial fibrillation ablation with cryoballoon
- Trial name
- NCT05513482
- Testing
- Tissue Doppler Imaging, M Mode Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa