Clinical trials: Photodynamic Therapy (PDT)
Halitosis
Evaluation of Halitosis After Treatment With Photodynamic Therapy Associated With Periodontal Treatment
The aim of this randomized, controlled clinical trial was to treat oral halitosis in healthy adults with photodynamic therapy associated with periodontal treatment and follow them up for 3 months.
- Trial name
- Halitosis (NCT03996915)
- Testing
- Pdt Photodynamic Therapy, tongue scrapper
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Central Serous Chorioretinopathy, Micropulse Laser
Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
In this study, patients with chronic central serous chorioretinopathy who were treated by micropulse laser alone or micropulse laser combined with photodynamic therapy without drugs are retrospectively included.
- Conditions
- Central Serous Chorioretinopathy, Micropulse Laser, Photodynamic Therapy
- Trial name
- NCT06468540
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital
Acne Vulgaris
Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in Adults
The aim of this study is to test the safety and efficacy of photodynamic therapy (PDT) for the medication Ameluz® performed with the PDT-lamp BF-RhodoLED® in comparison to the respective placebo treatment for moderate to severe…
- Trial name
- NCT05080764
- Testing
- 1h Incubation Photodynamic therapy (PDT) (ALA-PDT, Ameluz®-PDT), 1h Incubation Photodynamic therapy (PDT) (vehicle to BF-200 ALA containing no active ingredient), 3h Incubation Photodynamic therapy (PDT) (ALA-PDT, Ameluz®-PDT)
- Where
- 9 sites in United States
- Volunteers
- 120 people
- Sponsor
- Biofrontera Inc.
Halitosis
Evaluation of Halitosis After Treatment With Photodynamic Therapy
Halitosis is the term used to define an unpleasant odor emanating from the mouth. Some lung diseases, such as bronchiectasis, are among the extra-oral causes of this condition.
- Trial name
- NCT03973684
- Testing
- pdt experimental group, tongue scraper group
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Periodontitis
Efficacy of Photodynamic Therapy and LASER Disinfection in Periodontal Therapy for Treatment of Periodontitis
The goal of this clinical trial is to Investigate the clinical and microbiological efficacies of Laser disinfection and ICG-mediated aPDT as adjunct to RSD for patients with periodontitis.
- Trial name
- NCT06305533
- Testing
- LASER disinfection, Photodynamic therapy, Root surface debridement
- Where
- Iraq
- Volunteers
- 18 people
- Sponsor
- University of Baghdad
Port-wine Stain
A Pilot Study of Hemoporfin PDT in Children(2-7 Years Old) With Port-wine Stain
This pilot study aims to evaluate the safety and efficacy of hemoporfin photodynamic therapy (PDT) with different light doses for port-wine stain (PWS）in 2-7 years old children.
- Trial name
- NCT04106258
- Testing
- Hemoporfin PDT
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Organ Transplants
Prophylactic Photodynamic Therapy to Organ Transplant Patients
To evaluate a possible prophylactic efficacy of photodynamic therapy on the incidence of non-melanoma skin cancer, actinic keratoses, warts and keratoses in recently organ transplanted recipients.
- Trial name
- NCT00365521
- Testing
- Photodynamic Therapy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
Periodontal Disease
Evaluation of Photodynamic Therapy as an Adjunct to Non-surgical Treatment in Periodontitis in Smokers vs. Non-smokers
Patients with moderate periodontal destruction underwent mechanical debridement of the pathological changes from the periodontal pockets in one of the randomly selected quadrants and in another, also randomly selected, quadrant.
- Trial name
- NCT07697963
- Testing
- Photodynamic therapy (PDT)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pristina
Port Wine Stains
Enhanced Efficacy Through Optimization of Hemoporfin-Photodynamic Therapy Parameters in Port-Wine Stains
1. Background and Objectives Port-wine stain (PWS) is a congenital capillary malformation located in the upper dermis. Hematoporphyrin monomethyl ether (HMME)-mediated photodynamic therapy (PDT) has been established as a primary…
- Trial name
- NCT07353385
- Testing
- irradiation at 84 mW/cm² for 17 minutes per spot, irradiation at 75 mW/cm² for 19 minutes per spot
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Actinic Keratosis
Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK)
The purpose of this study is to determine if Levulan Photodynamic Therapy (PDT) is safe and effective in the treatment of actinic keratosis when applied to broad areas on the face and scalp for 1, 2 and 3 hours.
- Trial name
- NCT01475955
- Testing
- Broad Area ALA 1-hour incubation, Broad Area ALA 2 hour incubation, broad area ALA 3-hour incubation
- Where
- 13 sites in United States
- Volunteers
- 235 people
- Sponsor
- DUSA Pharmaceuticals, Inc.
Cholangiocarcinoma
Photodynamic Therapy (PDT) Trial for Palliation of Cholangiocarcinoma
This research study is a phase III double arm, multicenter, randomized controlled clinical trial comparing endoscopic retrograde cholangiopancreatography (ERCP) and stenting plus photodynamic therapy (PDT) versus ERCP with…
- Trial name
- PDT (NCT00907413)
- Testing
- ERCP and Photodynamic Therapy, ERCP only
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Actinic Keratosis, Sun Damaged Skin
Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin
Comparison of treatment efficacy and safety of pretreatment with ablative fractional laser versus microdermabrasion combined with large-area photodynamic therapy with methyl aminolevulinate for actinic keratoses
- Conditions
- Actinic Keratosis, Sun Damaged Skin, Solar Keratosis, Solar Skin Damage
- Trial name
- NCT03006185
- Testing
- Ablative Fractional Carbon Dioxide (CO2) Laser, Microdermabrasion
- Volunteers
- 18 people
- Sponsor
- Bispebjerg Hospital