Clinical trials: Photobiomodulation Therapy
Pediatric Anesthesia, Low Level Laser Theraphy
Efficacy of Low Level Laser Therapy on İnjection Pain
The purpose of this study was to compare the pain during needle insertion and injection in supraperiosteal anesthesia with either topical anesthesia (control) or LLTT (experimental).
- Trial name
- NCT04243811
- Testing
- Diode Laser, topical anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Okan University
Head and Neck Cancer, Trismus
Photobiomodulation and Sonophoresis Improving Jaw Mobility and Quality of Life Among Head and Neck Cancer Survivors
Head and neck cancer originate from the several different anatomical subsites especially the squamous cell carcinoma. This involves mainly Oropharynx, Hypopharynx, and Larynx.
- Trial name
- NCT04082793
- Testing
- Photobiomodulation therapy with mandibular exercises, Sonophoresis with mandibular exercises
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Breast Cancer, Radio Dermatitis
Photobiomodulation in Radiodermatitis in People With Breast Cancer
Most breast cancer patients undergoing radiotherapy develop radiodermatitis, making it one of the most prevalent adverse events during cancer treatment.
- Trial name
- NCT06990165
- Testing
- Photobiomodulation
- Where
- 2 sites in Brazil
- Volunteers
- 148 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Alopecia
A Clinical Comparison of FDA-Cleared Photobiomodulation Devices for the Treatment of Alopecia
Photobiomodulation is a form of non-ionizing light therapy has been shown to stimulate cellular processes and reduce inflammation as well as improve pain and wound healing.
- Trial name
- NCT06748287
- Testing
- iGrow Hair Growth System, Capillus352, HairMax Ultima 12 Lasercomb
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Minnesota
Breast Cancer
Low Level Laser Therapy for Hair Preservation With Chemotherapy for Breast Cancer
The purpose of this study is to see whether low level laser therapy can help maintain normal hair growth on the scalp in people receiving chemotherapy, which is generally associated with hair loss.
- Trial name
- NCT01081106
- Testing
- Low-Level Laser Therapy
- Sponsor
- Northwestern University
Breast Carcinoma, Cancer Survivor
Fractional CO2 Laser Therapy for Survivors of Breast Malignancies
This pilot clinical trial studies how well fraction carbon dioxide (CO2) laser therapy works in treating vaginal atrophy in patients with breast cancer.
- Conditions
- Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia
- Trial name
- NCT03307044
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Neoplasms Pancreatic
Percutaneous Immunostimulating Interstitial Laser Thermotherapy in Pancreatic Cancer
Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue…
- Trial name
- NCT03187587
- Testing
- imILT, Standard chemotherapy treatment
- Where
- Portugal
- Volunteers
- 8 people
- Sponsor
- Clinical Laserthermia Systems AB
Carpal Tunnel Syndrome, Pregnancy Related
Effects of High Intensity Laser on Mechanical and Physiological Findings in Pregnant Women With Carpal Tunnel Syndrome
This study will propose a novel approach to treat pregnant women with mild to moderate carpal tunnel syndrome (CTS) using the recently introduced High intensity laser therapy with its deep penetration and high-power…
- Trial name
- NCT04969393
- Testing
- High intensity laser therapy, Conventional Physical Therapy
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- October 6 University
Cardiovascular Diseases
Effects of the Low-level Laser Therapy on Inflammatory Profile of the Patients With Coronary Artery Bypass Surgery
Cardiovascular diseases are the leading causes of morbidity and mortality in Brazil and surgical procedures to treat these disorders have grown dramatically in recent years.
- Trial name
- NCT02709499
- Testing
- 0J LLLT, 6J LLLT
- Volunteers
- 38 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Osteoarthritis, Knee
Efficacy of High-Intensity Laser Therapy in Early-Stage Symptomatic Knee Osteoarthritis
This randomized, double-blind, sham-controlled clinical trial evaluated the effectiveness of high-intensity laser therapy (HILT) in patients with early-stage symptomatic knee osteoarthritis.
- Trial name
- HILT-ESCOA (NCT07859878)
- Testing
- High-Intensity Laser Therapy (HILT), Standardized Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ege University
Achilles Tendinopathy
Shockwave, Photobiomodulation, and Physical Therapy for Achilles Tendinopathy
The goal of this clinical trial is to learn more about and compare the effectiveness of standard of care (SOC) physical therapy (PT), PT with photobiomodulation therapy (PBMT; low-level laser therapy), PT with shockwave therapy…
- Trial name
- NCT05751785
- Testing
- Physical Therapy, Shockwave Therapy, Photobiomodulation Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Musculoskeletal Injury Rehabilitation Research for Operational Readiness
Myogenic Temporomandibular Joint Disorders
Low Level Laser Therapy and Rocabado's Approach for Myogenic TMJ Disorders
Rocabado's 6x6 exercises are designed to improve muscular co-ordination, relax tense muscles, increase temporomandibular joint (TMJ) ROM, alter the jaw closure pattern and muscle strength.
- Trial name
- NCT07026617
- Testing
- Rocabado's approach in addition to LLLT, control group
- Volunteers
- 42 people
- Sponsor
- Cairo University
Depression
Transcranial Photobiomodulation for the Treatment of Pediatric Depression
An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving symptoms of depression in youth.
- Trial name
- NCT04579185
- Testing
- Transcranial Photobiomodulation
- Sponsor
- Massachusetts General Hospital
Arthroplasty, Replacement, Hip
Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty
Osteoarthritis (OA), a chronic degenerative muscle disease characterized by cartilage wear, causes progressive joint deformity and loss of function leading to the indication of total hip arthroplasty (THA), when conservative…
- Trial name
- NCT02970890
- Testing
- Portable Pain Away™
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Adriane Aver Vanin
Autism
Photobiomodulation on Core Symptoms of Autism
This study aims to evaluate the effectiveness of photobiomodulation therapy on core symptoms in children with autism spectrum disorder.
- Trial name
- NCT07542899
- Testing
- Photobiomodulation
- Volunteers
- 30 people
- Sponsor
- Suez University
Oropharyngeal Mucositis, Myeloablative Hematopoietic Cell Transplantation
Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients
Oral mucositis (OM) is a painful and potentially debilitating acute toxicity that frequently affects children undergoing hematopoietic cell transplantation (HCT).
- Conditions
- Oropharyngeal Mucositis, Myeloablative Hematopoietic Cell Transplantation, Low Level Light Therapy
- Trial name
- NCT02119897
- Testing
- Low Level Light Therapy
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Dana-Farber Cancer Institute
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Oral Mucositis
Prevention of Oral Mucositis Using Photobiomodulation Therapy
Oral mucositis is a significant and common toxicity experienced by patients who receive high-dose chemotherapy as a preparatory regimen for a hematopoietic cell transplant (HCT).
- Trial name
- NCT04227340
- Testing
- Photobiomodulation Therapy (PBM), Pain and Oral Function Assessment, Parent-Reported Satisfaction Survey
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- St. Jude Children's Research Hospital
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Photobiomodulation Therapy
Reversal of Anaesthesia with Diode Laser
Background: After local anesthesia, which is frequently used in pediatric dentistry, long-term soft tissue numbness can cause various problems.
- Trial name
- NCT06841120
- Testing
- Actual laser application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
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