Clinical trials: Photoaging
Fine Lines, Wrinkle
A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum
This double-blind, randomized, controlled, single-center clinical trial was conducted to assess the efficacy and tolerance of an anti-aging serum to improve moderate overall photodamage and skin fatigue of aging skin after 7 days…
- Conditions
- Fine Lines, Wrinkle, Photoaging
- Trial name
- NCT05271136
- Testing
- Anti-aging Serum, Facial Moisturizer, Cleansing Lotion
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Sun Damaged Skin
An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light
The purpose of this project is to obtain clinical data, including skin samples, that will help investigators evaluate changes occurring in sun damaged human skin as a result of light that simulates sun exposure (Solar Simulated…
- Trial name
- NCT05398237
- Testing
- Solar Simulated Light (SSL)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Skin Aging, Skin Cancer
Bioclinical Study of Scalp Photoaging of a Population Male Over 65 Years Old.
The aging of skin, especially that of the scalp, is a combination of intrinsic and extrinsic aging factors secondary to the chronic sun exposure.
- Trial name
- BACCHUS (NCT03603587)
- Testing
- biopsy, blood sample, questionnaire on sun exposure
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aging, Skin Laxity
Association of Leucocyte Telomere Length With DPAS Score in Skin Aging
The goal is to know the profile of photoaging based on clinical examination, Dermoscopic Photoaging Scale and leucocyte telomere length The main questions of Research are: what is the profile of photoaging based on clinical…
- Trial name
- NCT06501547
- Testing
- Leucocyte Telomere Length from blood draw
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Photoaging, Skin Aging
AI-Personalized Skincare Regimen for Facial Photoaging in Women
The goal of this clinical study was to learn whether a skincare regimen personalized by an artificial intelligence (AI) skin-analysis tool improves signs of facial skin aging in women aged 35 to 65 with mild-to-moderate facial…
- Trial name
- NCT07879833
- Testing
- AI-personalized skin longevity regimen
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- MDalgorithms Inc.
Mucosal Melanoma, Acral/Lentiginous Melanoma
Imatinib in Patients With Mucosal or Acral/Lentiginous Melanoma
The purpose of this study is to evaluate how effective imatinib (Gleevec) is in treating acral/lentiginous and mucosal melanoma which has spread to other parts of the body in patients who's disease carries a c-kit mutation.
- Conditions
- Mucosal Melanoma, Acral/Lentiginous Melanoma, Chronically Sun Damaged Melanomas
- Trial name
- BUS255 (NCT00424515)
- Testing
- Imatinib
- Where
- 5 sites in United States
- Volunteers
- 24 people
- Sponsor
- Dana-Farber Cancer Institute
Wrinkle, Photoaging
Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging
The intended use of the radiofrequency and microneedling devices used in this study is to assess the efficacy and safety of paired treatment for the treatment of facial aging.
- Conditions
- Wrinkle, Photoaging, Dyschromia
- Trial name
- NCT05388604
- Testing
- RF device, Microneedling device
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Cynosure, Inc.
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
The purpose of this study is to determine whether a one-time injection of allogeneic mesenchymal bone marrow cells is safe and beneficial in the treatment of photodamage on the face.
- Trial name
- NCT01771679
- Testing
- Allogeneic Mesenchymal Bone Marrow Cells
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Stemedica Cell Technologies, Inc.
Photoaging
Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational
The purpose of this study is to determine the improvement in signs of photoaging and subject satisfaction after combination, global facial and/or neck treatment with IncobotulinumA (Xeomin), HA (Belotero) and/or calcium…
- Trial name
- NCT05039723
- Testing
- Radiesse, Xeomin, Belotero
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Main Line Center for Laser Surgery
Photoaging
The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin
This study is a double-blind randomized vehicle-controlled study assessing how Zinc Di-(dibutyryl lisinate) (Z-DBL) influences skin biophysical measures such as skin hydration, transepidermal water loss, and elasticity, as well…
- Trial name
- NCT06096649
- Testing
- Topical Vehicle + Zinc Di-(dibutyryl lisinate), Topical Vehicle
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Photoaging
Efficacy and Safety of Profile HaloTM Mixed Fractional Laser on Treating of Facial and Neck Photoaging.
1. Fractional laser has become an important laser modality in management of a number of skin conditions and photoaging. Fractional photothermolysis is the fractional emission of light into microscopic treatment zones, creating…
- Trial name
- NCT03948945
- Testing
- Profile HaloTM Mixed Fractional Laser
- Volunteers
- 15 people
- Sponsor
- xjpfW
Photoaging, Epidermal p53 Expression
Oral Isotretinoin for Photoaging: Results of a Randomized Controlled Phase II Trial
A clinical and histological randomized controlled phase II trial to evaluate the efficacy and safety of oral isotretinoin for treating photoaging was performed with 32 menopausal or sterilized women aged 40-55y.
- Trial name
- NCT00701740
- Testing
- oral isotretinoin and Mexoryl SX / XL, Mexoryl XL / SX
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of São Paulo
Skin Manifestations, Wrinkle
A 56-day Clinical Study on Facial Skin Rejuvenation
This clinical trial aims to learn about the efficacy of MLYAAT-1002® (a proprietary anti-aging complex, MLYAAT is short for "multi-layer anti-ageing technology" ) in female subjects who have newly received the rejuvenation…
- Conditions
- Skin Manifestations, Wrinkle, Photoaging
- Trial name
- NCT06188338
- Testing
- Fractional picosecond laser treatment followed by daily use of formulations containing MLYAAT-1002®., Fractional picosecond laser treatment followed by daily use of formulations without MLYAAT-1002®
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Other Benign Neoplasm of Skin, Unspecified
Eflornithine and/or Diclofenac in Treating Patients With Sun-Damaged Skin
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of eflornithine and diclofenac may stop cancer from growing in patients with sun-damaged skin.
- Trial name
- NCT00601640
- Testing
- Diclofenac Na gel, Eflornithine HCL ointment
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Arizona
Healthy Volunteers
The Effect of Arabica Gayo Cascara Pulp Extract on Photoaging
The purpose of this study was to assess the safety of Gayo Arabica coffee pulp extract cream as an antioxidant for the skin that can increase skin moisture
- Trial name
- NCT05390489
- Testing
- Cascara pulp arabica gayo coffee cream
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wahyu Lestari
Tobacco Addiction, Smoking Related Diseases
A Photoaging Mobile App Promoting Poster Campaign for Preventing Smoking in Secondary Schools
The purpose of this study is to determine whether photoaging mobile app promoting poster campaigns are effective to reduce smoking prevalence among adolescents in Germany. This is measured via questionnaire.
- Conditions
- Tobacco Addiction, Smoking Related Diseases, Adolescent Smoking
- Trial name
- Smokerface (NCT02544360)
- Testing
- Photoaging mobile app promoting poster campaign.
- Where
- Germany
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Sun Damaged Skin
Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects
The purpose of this study is to evaluate the efficacy of topical products in providing protection against the visible light and ultraviolet A1 (UVA1) part of sunlight.
- Trial name
- NCT04181476
- Testing
- Sunscreening Agents
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Photoaging, Hyperpigmentation
Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging
Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles.
- Conditions
- Photoaging, Hyperpigmentation, Rhytides
- Trial name
- NCT04586816
- Testing
- 1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Actinic Keratosis
Tirbanibulin 1% Ointment for the Treatment of Chronically Sun-damaged Skin on the Face
Interventional, monocentric, national, single-arm, uncontrolled, open, prospective phase IV study. Since this study is not powered for confirmative testing, analysis is done by descriptive statistics Eligible AK patients receive…
- Trial name
- SunDamage (NCT05900258)
- Testing
- Tirbanibulin
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Medical University of Graz