Clinical trials: Photoaging
Fine Lines, Wrinkles
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin…
- Conditions
- Fine Lines, Wrinkles, Photoaging
- Trial name
- NCT04545970
- Testing
- Facial cleanser, Facial moisturizer, Sunscreen
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Aging
Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles
This research study will test how well a light therapy mask works for women with mild to moderate hyperpigmentation (brown spots) and moderate to severe facial wrinkles, as compared to a "sham" or inactive investigational light…
- Trial name
- NCT03312543
- Testing
- Active Mask
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Skin Aging, Sun Damaged Skin
The Effects of an LED Face Mask & Neck and Chest Mask On Skin Health
This 12-week single-group virtual study evaluates the effects of the iRESTORE Illumina LED Face Mask and Neck \& Chest Mask on skin health in adult females.
- Trial name
- NCT07025837
- Testing
- iRESTORE Illumina LED Face Mask and Neck & Chest Mask
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Freedom Laser, Inc.
Erythema, Sun Damaged Skin
Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema
The aim of this study is to determine the erythema-reducing efficacy of a test product in two concentrations on a light sunburn induced by a sun simulator compared to an untreated control and a placebo product.
- Conditions
- Erythema, Sun Damaged Skin, Skin Inflammation
- Trial name
- NCT05300542
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Photoaging, Wrinkle
A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum
This double-blind, randomized, placebo-controlled, single-center clinical trial was conducted to assess the efficacy and tolerance of an anti-aging daily serum to improve moderate overall photodamage and skin fatigue after…
- Trial name
- NCT05514782
- Testing
- Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 40+
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaged Facial Skin, Photoaging
Study of RRS® HA Long Lasting for Improving Facial Wrinkles and Skin Quality
The objective of this clinical study is to confirm the clinical performance and long-term safety of the CE-marked RRS® HA Long Lasting in the treatment of skin photoaging and its consequences, with a primary focus on improving…
- Conditions
- Photoaged Facial Skin, Photoaging, Wrinkle Reduction, Skin Quality Improvement
- Trial name
- ORACLE LL (NCT07551609)
- Testing
- RRS® HA Long Lasting
- Where
- 6 sites in Spain
- Volunteers
- 207 people
- Sponsor
- Skin Tech Pharma Group S.L.U.
Photoaging, Hyperpigmentation
Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging
Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles.
- Conditions
- Photoaging, Hyperpigmentation, Rhytides
- Trial name
- NCT04586816
- Testing
- 1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation
Wrinkle, Photoaging
Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging
The intended use of the radiofrequency and microneedling devices used in this study is to assess the efficacy and safety of paired treatment for the treatment of facial aging.
- Conditions
- Wrinkle, Photoaging, Dyschromia
- Trial name
- NCT05388604
- Testing
- RF device, Microneedling device
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Cynosure, Inc.
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Anti-aging, Photoaging
A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+
The primary objective of this study is to evaluate the efficacy and tolerance of a moisturizer SPF 50+ when used over a 12-week time period by women with moderate to severe facial photodamage.
- Trial name
- NCT06148558
- Testing
- Sunscreen Moisturizer, Gentle Cleansing Lotion, Facial Moisturizer
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Atrophy, Hemifacial, Elastosis
A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity
A Clinical Trial Evaluating Efficacy of a Skin Cream Targeting Dermal Fat in Improving the Skin Elasticity of Healthy Volunteers.
- Conditions
- Atrophy, Hemifacial, Elastosis, Photoaging
- Trial name
- NCT04769193
- Testing
- Adipeau face cream
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Adipeau Inc.
Actinic Keratosis
A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on Actinic Keratosis on Face or Scalp (AK004)
This Phase III study was designed to evaluate the efficacy and safety of KX2-391 Ointment 1% in adult participants when applied to an area of skin containing 4-8 stable, clinically typical actinic keratosis (AK) lesions on the…
- Trial name
- NCT03285490
- Testing
- KX2-391 Ointment 1%
- Where
- 30 sites in United States
- Volunteers
- 351 people
- Sponsor
- Almirall, S.A.
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging
Effects of Dietary Soy Protein on Facial Wrinkles in Postmenopausal Women
Soy and soy-derived products are the primary dietary sources of isoflavones, particularly daidzein and genistein, for humans. Isoflavones are noted to have several effects on the skin including proliferation of keratinocytes…
- Trial name
- NCT04871750
- Testing
- Soy protein, Casein protein
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation
This randomized, single-center, double-blinded, controlled, clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after radiofrequency microneedling and…
- Trial name
- NCT06157853
- Testing
- Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging, Wrinkle
Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles
This study is being conducted to improve standards of care in the cosmetic treatment of sun damage, fine lines, and wrinkles. VI Peels® and Botox® have been used cosmetically to improve patient concerns as monotherapies.
- Conditions
- Photoaging, Wrinkle, Sun Damaged Skin
- Trial name
- NCT05162300
- Testing
- Same Day Intervention of VI Peel (Procedure) and Botulinum Toxin (Drug)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vitality Institute Medical Products
Keratosis, Actinic
A Study to Evaluate the Efficacy and Safety of Tirbanibulin Ointment in Adult Participants With Actinic Keratosis
The purpose of the study is to evaluate the efficacy and safety of tirbanibulin 10 milligrams per gram (mg/g) ointment when applied to a treatment field (TF) larger than 25 square centimeters (cm^2) and up to 100 cm^2 in adult…
- Trial name
- TirbAKare (NCT06135415)
- Testing
- Tirbanibulin, Vehicle ointment
- Where
- 35 sites in Germany, Italy and 3 more
- Volunteers
- 280 people
- Sponsor
- Almirall, S.A.
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation
This randomized, multi-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after hybrid-fractional…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06436261
- Testing
- Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Revision Skincare