Clinical trials: Phantom Limb Pain After Amputation
Rehabilitation
Motor Imagery Practice on Amputees (MIPA)
Motor imagery practice (MIP), which is the repeated internal representation of a movement without engaging its physical execution and which shares a neurofunctional equivalence with physical practice, has been show to contribute…
- Trial name
- MIPA (NCT03125538)
- Testing
- Motor Imagery, Control Task
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Laboratoire Interuniversitaire de Biologie de la Motricité
Amputation
Mirror Therapy for Phantom Limb Pain
This study, conducted at the National Institutes of Health (NIH) and at Walter Reed Army Medical Center (WRAMC), will explore the phenomenon of phantom limb pain (a continued feeling of pain in an amputated limb) and will use…
- Trial name
- NCT00623818
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750525
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Phantom Pain
Neural Bases of Phantom Pain After Amputation
The amputation of a limb results in chronic pain associated with the lost limb in the majority of patients, which persists over time.
- Trial name
- Phantom limb (NCT05545358)
- Testing
- Questionnaires, Brain and Spinal Cord functional Magnetic Resonance Imaging, Proprioceptive training
- Volunteers
- 75 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Neuropathic Pain
Brain Computer Interface and Virtual Reality (BCI-VR) for Pain Treatment
Pilot Interventional study with minimal risks and constraints, prospective, monocentric. Safety and Efficacity evaluation of a Novel Medical Device.
- Trial name
- GHOST (NCT03889353)
- Testing
- BCI sessions
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Nantes University Hospital
Somatosensory Perception Following Lower Limb Amputation
Spinal Cord Stimulation (SCS) for Amputees
The purpose of this study is to investigate how leg amputee patients can feel sensations with neuromodulation while they are using a prosthetic leg.
- Trial name
- NCT04490382
- Testing
- 32 channel external stimulator
- Sponsor
- Duke University
Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee
Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System
This study tests whether a vibration-based feedback device (Suralis) can reduce phantom limb pain in people with lower-leg amputations over 3 weeks.
- Conditions
- Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee, Lower Limb Amputation Below Knee, Lower Limb Amputation Knee
- Trial name
- NCT07324109
- Testing
- Vibrotactile sensory feedback
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Median
Amputation, Phantom Limb
Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
Research study to determine if putting local anesthetic-or numbing medication-through one or two tiny tube(s) placed next to the nerves that go to an amputated limb will decrease phantom limb and/or stump pain.
- Conditions
- Amputation, Phantom Limb, Stump Pain
- Trial name
- NCT00667264
- Testing
- perineural ropivacaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, San Diego
Pain, Phantom, Pain, Neuropathic
Valproic Acid for the Prevention of Post-Amputation Pain
The objectives of this study are, to test the effectiveness of Valproic Acid (VPA) in the prevention of chronic neuropathic and post-amputation pain, as well as to further define the underlying inflammatory and epigenetic…
- Trial name
- NCT01928849
- Testing
- Valproic Acid, Cherry Syrup
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Phantom Limb, Residual Limb Pain
Acupuncture for the Treatment of Phantom Limb and Residual Limb Pain After Amputation
The purpose of this study is to identify the best treatment sequence and combination of acupuncture points for the treatment of phantom limb or residual limb pain in the traumatic/surgical amputee.
- Conditions
- Phantom Limb, Residual Limb Pain, Traumatic Amputation, Amputation
- Trial name
- NCT00388752
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Walter Reed Army Medical Center
Neuroma, Cryoablation
Proximal Nerve Cryoablation Versus Perineuroma Cryoablation for Chronic Neuroma Pain After Combat-Related Amputation
atients with combat-related amputations frequently develop chronic neuroma pain that interferes with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Trial name
- AXON-FREEZE (NCT07618689)
- Testing
- Perineuroma Cryoablation, Proximal Nerve Cryoablation
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Pain, Pain After Surgery
Tourniquet Exposure and Risk of Chronic Pain After Severe Limb Trauma
Severe limb trauma often requires the use of a tourniquet to stop life-threatening bleeding. While tourniquets are essential for saving lives, prolonged interruption of blood flow may lead to tissue ischemia, nerve injury, and…
- Conditions
- Pain, Pain After Surgery, Phantom Limb Pain After Amputation, Military Combat Stress Reaction
- Trial name
- TOURNI-PAIN (NCT07475871)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Pain Management, Pain
Silencing Neuroma Pain-Botulinum Toxin Versus Local Anesthetic Injection
Neuroma-related pain is a frequent and disabling condition after limb trauma and amputation. Available treatments often provide short-lasting or insufficient analgesia.
- Conditions
- Pain Management, Pain, Phantom Limb Pain, Phantom Limb Pain After Amputation
- Trial name
- SILENCE-NEUROM (NCT07431944)
- Testing
- Botulinium toxin type A injection, Local Anesthesia
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Phantom Limb Pain, Stump Neuralgia
Cryolesion in Treatment of Phantom Limb Pain
Assessment of pain intensity on the NRS. Assessment of the quality of life by SF-36 and AIS. Diagnostic/prognostic nerve block with 5 ml of 2% lidocaine under real-time ultrasound control with confirmation of the correct position…
- Conditions
- Phantom Limb Pain, Stump Neuralgia, Pain, Phantom
- Trial name
- NCT03415360
- Testing
- cryoablation
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Military Institute od Medicine National Research Institute
Phantom Limb Pain
Telerehabilitation Using Mirror Therapy in Patients With Phantom Limb Pain Following Lower Limb Amputation.
The overall aim of this randomized controlled study is to investigate the effectiveness of mirror therapy supported by telerehabilitation on the intensity, duration and frequency of phantom limb pain and daily activities compared…
- Trial name
- NCT02076490
- Testing
- Physical/Occupational therapy
- Volunteers
- 105 people
- Sponsor
- Zuyd University of Applied Sciences
Lower Extremity Surgical Amputation, Post-amputation Phantom Limb Pain
Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
When a limb is amputated, pain perceived in the part of the body that no longer exists often develops, called "phantom limb" pain.
- Trial name
- NCT03461120
- Testing
- Experimental continuous peripheral nerve blocks, Control continuous peripheral nerve blocks
- Where
- 8 sites in United States
- Volunteers
- 208 people
- Sponsor
- University of California, San Diego
VTE (Venous Thromboembolism), Phantom Limb Pain After Amputation
Venous Thromboembolism and Chronic Pain After Major Limb Trauma
Major limb trauma is associated with a high risk of venous thromboembolism (VTE) due to systemic inflammation, endothelial injury, immobilization, and hypercoagulability.
- Conditions
- VTE (Venous Thromboembolism), Phantom Limb Pain After Amputation, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- THROMBO-PAIN (NCT07475910)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Post-Amputation Phantom Limb Pain
Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study
When a limb is severed, pain perceived in the part of the body that no longer exists often develops and is called "phantom limb" pain.
- Trial name
- NCT03449667
- Testing
- Cryoneurolysis
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Phantom Limb Pain
The Effect of Distant Reiki on Pain and Holistic Well-being
Phantom limb pain is a condition characterized by painful sensations in the missing part of the amputated limb, which reduces the quality of life of the individual.
- Trial name
- NCT05684445
- Testing
- Distant reiki group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Aksaray University Training and Research Hospital
Amputation, Phantom Pain Following Amputation of Lower Limb
Effectiveness of Mirror Therapy in Patients With Amputations of Lower Limbs of Vascular Origin
The aim of this study is to assess the efficacy of the mirror therapy on phantom pain for patients with amputation after vascular etiology.
- Trial name
- MIR-PHAN (NCT03149432)
- Testing
- Mirror Therapy, Gabapentin, Rehabilitation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805