Clinical trials: Personality Disorders, open to volunteers
Borderline Personality Disorder (BPD)
Application and Effectiveness of the STEPPS in Patients with BPD, Extending to Their Families with the FC Program
The present research project is framed within the issue of Borderline Personality Disorder (BPD). This condition stands as one of the most common challenges encountered within the mental health services of the National Health…
- Trial name
- NCT06195553
- Testing
- STEPPS plus Family Connections, STEPPS
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universitat Jaume I
Schizophrenia Disorders
An Integrated Neurophysiological Approach Toward the Early Detection of Psychiatric Disorders
Schizophrenia (SCZ) is a severe neuropsychiatric disorder characterized by cognitive decline, social withdrawal, and positive symptoms such as hallucinations and delusions.
- Trial name
- NCT06886945
- Testing
- Audio-Visual Perceptual Tasks
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Psychopathy
Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture
This clinical trial will examine whether transcranial magnetic stimulation (TMS), a noninvasive form of brain stimulation, can influence social cognition, cognitive processing, and brain function in adults with elevated…
- Trial name
- NCT07635940
- Testing
- continuous theta burst stimulation (cTBS), Intermittent theta burst stimulation (iTBS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Psychosis, Prodromal Schizophrenia
Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability…
- Conditions
- Psychosis, Prodromal Schizophrenia, Prodromal Symptoms
- Trial name
- SCORES (NCT05131035)
- Testing
- SCORES (Specific COgnitive Remediation with Support)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Anti Social Behavior
Evaluating the Feasibility and Effects of PULS
Background Youth involved in criminal groups represent a growing, high-risk population within Swedish institutional care, with elevated rates of recidivism and poor long-term outcomes.
- Trial name
- PULS on SiS (NCT07772128)
- Testing
- PULS, TAU
- Volunteers
- 224 people
- Sponsor
- Karolinska Institutet
Chronic and Episodic Headache, Headache Disorders
PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE
Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature.
- Trial name
- AURA (NCT07268768)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Borderline Personality Disorder, Borderline Personality Pathology
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
ADEPT is an open-label proof-of-concept study evaluating the safety and tolerability of psilocybin-assisted therapy in conjunction with Dialectical Behavior Therapy for participants with borderline personality disorder.
- Conditions
- Borderline Personality Disorder, Borderline Personality Pathology, Depressive Symptoms, Emotion Dysregulation
- Trial name
- ADEPT (NCT07833761)
- Testing
- Psilocybin, Psilocybin-Assisted Therapy With Dialectical Behavior Therapy
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of Minnesota
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Alcohol Use Disorder, Cognition Disorders
Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations.
- Trial name
- TIPA (NCT07468825)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Myeloid Leukemia, Chronic Phase Chronic Myelogenous Leukemia
Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts w/Chronic Myeloid Leukemia
This is an observational pilot study to examine the association between a patient's personality and adherence to tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia.
- Trial name
- NCT06229860
- Testing
- Interview
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Irvine
Borderline Personality Disorder
The Influence of Treatment Format on Schema Therapy for Borderline Personality Disorder
The goal of this clinical trial is to compare etc. in patients with borderline personality disorder pure individual schema therapy to combined individual-group schema therapy.
- Trial name
- IST-IGST (NCT05986552)
- Testing
- Individual Schema Therapy (IST), Individual-Group Schema Therapy (IGST)
- Where
- 3 sites in Netherlands
- Volunteers
- 132 people
- Sponsor
- University of Amsterdam
Obsessive - Compulsive Disorder
Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder
This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy.
- Trial name
- NCT07146438
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Supportive Therapy (ST), Exposure and Response Prevention (ERP) Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Adam Frank
Obsessive - Compulsive Disorder
Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for OCD
This randomised controlled trial (RCT) aims to assess the feasibility, acceptability, and preliminary efficacy of a culturally adapted, guided self-help cognitive behaviour therapy (CBT) manual specifically designed for…
- Trial name
- NCT07239401
- Testing
- Culturally adapted Guided Self-Help OCD Manual
- Volunteers
- 108 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Antisocial Behavior
Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders
The goal of this clinical trial is to investigate the effect of two types of cognitive remediation training on real-world behavioral outcomes including substance use, institutional adjustment, and recidivism following release…
- Trial name
- MCT (NCT06981351)
- Testing
- Attention to Context (ATC) training, Affective Cognitive Control (ACC) training
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- The Mind Research Network
Social Cognition, Personality Disorder
Neurocomputational Dynamics of Cooperation
The purpose of this study is to understand brain function, how people make decisions when they interact with others, and how brain function and behavior relate to personality traits.
- Conditions
- Social Cognition, Personality Disorder, Mental Health, Interpersonal Conflict
- Trial name
- COBRA (NCT07759973)
- Testing
- Social Learning Task Battery, Clinical Cohort, Social Learning Task Battery, Online Cohort
- Where
- United States
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Psychosis
Immune Mechanisms of Antipsychotic Treatment Response
The aim of this study is to investigate the role of the immune system in psychotic symptoms and their response to treatment. The investigators will collect blood and cerebrospinal fluid samples from participants with psychosis…
- Trial name
- IMAT (NCT06687694)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- King's College London
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Affective Disorders, Rumination
Study on the Effectiveness of Journaling as an add-on to Cognitive Behavioral Therapy
The aim of the present study is to examine the effects of keeping a therapy journal (journaling) on the effectiveness of cognitive behavioral therapy (CBT).
- Conditions
- Affective Disorders, Rumination, Childhood Trauma, Eating Disorder
- Trial name
- NCT06863909
- Testing
- Journaling, Treatment as Usual (TAU)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Schizophrenia Prodromal, SCHIZOPHRENIA 1 (Disorder)
Online Intervention To Improve Motivation
Participants will complete one online intervention lasting 12 weeks. Each week, they will be asked to complete a 20-30 minute session online.
- Conditions
- Schizophrenia Prodromal, SCHIZOPHRENIA 1 (Disorder), Psychosis
- Trial name
- Online Mot (NCT07157293)
- Testing
- Online Motivation Enhancing Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Autism Spectrum Disorder
DSM-5 Personality Disorders in Adults With Autism
Rationale: Self-report measures are frequently used for research and clinical assessments of adults with autism spectrum disorder (ASD).
- Trial name
- NCT06726187
- Testing
- Structured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ).
- Where
- Netherlands
- Volunteers
- 102 people
- Sponsor
- Parnassia Groep