Clinical trials: Peritonitis, active
SBP - Spontaneous Bacterial Peritonitis
Nitazoxanide in Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a life-threatening complication of liver cirrhosis characterized by infection of ascitic fluid in the absence of an evident intra-abdominal source.
- Trial name
- NCT07808450
- Testing
- Nitazoxanide (NTZ)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
ESRD, Disorders Associated With Peritoneal Dialysis
Peritoneal Dialysis Registration System (PERSIST)
Brief Summary: The investigators are registering all PD patients at recruited hospitals and developing a PD database in China. Patients will be followed up every 3 months, and both baseline and follow-up information will be…
- Trial name
- NCT02989298
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Fecal Peritonitis, Secondary Peritonitis
Vacuum Assisted Closure Versus On-demand Relaparotomy in Patients With Fecal or Diffuse Peritonitis
Multicenter randomized controlled trial including patients with fecal or diffuse peritonitis to either vacuum assisted closure or relaparotomy "on-demand".
- Conditions
- Fecal Peritonitis, Secondary Peritonitis, Diffuse; Peritonitis
- Trial name
- VACOR (NCT03932461)
- Testing
- Vacuum assisted closure, Relaparotomy "on demand"
- Where
- Denmark
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Liver Cirrhosis
Faecal Microbiota Transplantation for Liver Cirrhosis
The purpose is to investigate the effect of faecal microbiota transplantation (FMT) on complications, progression, and mortality of patients with liver cirrhosis.
- Trial name
- CHiFT (NCT04932577)
- Testing
- Faecal microbiota transplantation
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- University of Aarhus
Spontaneous Bacterial Peritonitis
Prediction of SBP in Cirrhotic Patients by Platlet Count, Na and AlBl Index.
This study aims to evaluate whether integrating serum sodium levels and platelet count with the Albumin-Bilirubin (ALBI) score can improve the early prediction of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with…
- Trial name
- NCT07116369
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Spontaneous Bacterial Peritonitis
Oral Gemifloxacin Versus Intravenous Cefotaxime in Treatment of Spontaneous Bacterial Peritonitis
oral Gemifloxacin versus intravenous Cefotaxime in treatment of spontaneous bacterial peritonitis
- Trial name
- NCT04168099
- Testing
- Cefotaxime, Gemifloxacin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Spontaneous Bacterial Peritonitis, Paracentesis
Optimal Treatment Strategy for Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a serious infection that occurs in patients with liver cirrhosis and ascites and is associated with substantial morbidity and mortality.
- Conditions
- Spontaneous Bacterial Peritonitis, Paracentesis, Treatment Efficacy, Adverse Events
- Trial name
- NCT07923318
- Testing
- Routine Follow-up Paracentesis at 48 Hours, Other
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Chonnam National University Hospital
Acute Complicated Appendicitis With Diffuse Peritonitis
Laparoscopic Versus Open Appendectomy Plus Peritoneal Lavage for Acute Complicated Appendicitis Patients With Diffuse Peritonitis
This study aim to evaluate the efficacy and safety of laparoscopic versus open appendectomy in the treatment of acute complicated appendicitis with diffuse peritonitis.
- Trial name
- NCT06633744
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
SBP - Spontaneous Bacterial Peritonitis
N-Acetylcysteine in the Management of Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is one of the most serious infectious complications of liver cirrhosis and ascites. It affects approximately 10-30% of hospitalized patients with decompensated cirrhosis and carries an…
- Trial name
- NCT07803952
- Testing
- NAC
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Appendicitis, Perforated Appendicitis
Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis
Acute appendicitis is one of the most common surgical emergencies in children. In complicated cases, where the appendix has perforated, become gangrenous, or caused peritonitis and purulent contamination, determining the optimal…
- Conditions
- Appendicitis, Perforated Appendicitis, Gangrenous Appendicitis, Peritonitis
- Trial name
- NCT07879235
- Testing
- Laparoscopic Appendectomy, Open Appendectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Appendicitis With Perforation, Appendectomy
Effect of Probiotic's Consumption on Several Markers in Perforated Appendix Patients With Diffuse Peritonitis
Does the administration of the probiotic Lactobacillus plantarum sp. have an impact on reducing leukocyte levels, segmented neutrophil counts, postoperative pain, and length of hospitalization in patients with diffuse peritonitis…
- Conditions
- Appendicitis With Perforation, Appendectomy, Probiotic
- Trial name
- NCT06856434
- Testing
- Lactobacillus plantarum sp Probiotic
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Padjadjaran
Peritonitis, Sepsis
Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis
The aim of this prospective, randomized, controlled trial is to provide evidence for adjuvant IgGAM treatment with regard to 1. Improvement of patient outcomes for peritonitis.
- Conditions
- Peritonitis, Sepsis, Septic Shock
- Trial name
- PEPPER (NCT03334006)
- Testing
- Pentaglobin®/Standard of Care
- Where
- 20 sites in Austria, Germany
- Volunteers
- 200 people
- Sponsor
- RWTH Aachen University
Cirrhosis, Spontaneous Bacterial Peritonitis
Early Ascitis Parencentesis in SBP
Paracentesis at 48 hours, as recommended in international guidelines, could delay the time to effective antibiotic therapy in cases of SBP with germs resistant to empirical antibiotic therapy.
- Trial name
- PAPISLA (NCT06679842)
- Testing
- ascitis paracentesis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Colorectal Cancer Metastatic, Peritoneal Carcinomatosis
Galunisertib Combined With Capecitabine in Advanced CRC With PM
This is a two-center open-label non-randomized proof of principle study consisting of a dose-finding part (phase I) and phase II study with Simon two-stage design investigating the anti-tumor activity of the combination of…
- Trial name
- NCT05700656
- Testing
- Galunisertib plus capecitabine
- Where
- 2 sites in Netherlands
- Volunteers
- 31 people
- Sponsor
- The Netherlands Cancer Institute
Spontaneous Bacterial Peritonitis
Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis
Norfloxacin versus Norfloxacin with Itopride in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis
- Trial name
- NCT04161768
- Testing
- Norfloxacin, Itopride
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Spontaneous Bacterial Peritonitis
Frequency and Predictors of Recurrent SBP in Cirrhotic Patients in Al Rajhi University Hospital
Assess the frequency of recurrent SBP in ascitic cirrhotic patients. Determine the predictive factors of recurrence after the first episode of SBP in ascitic cirrhotic patients
- Trial name
- NCT06778616
- Where
- 2 sites in Egypt
- Volunteers
- 101 people
- Sponsor
- Assiut University
Complicated Diverticulitis, Acute Diverticulitis
AIDE: Decision Support for Anastomosis or Colostomy in Emergency Surgery for Complicated Acute Diverticulitis
The AIDE/OBS study is a multicenter, observational, non-interventional study designed to collect standardized clinical, radiological, intraoperative visual, and surgical reasoning data from adult patients undergoing non-elective…
- Conditions
- Complicated Diverticulitis, Acute Diverticulitis, Peritonitis, Perforated Diverticulitis
- Trial name
- AIDE/OBS/2025 (NCT07651072)
- Testing
- Primary anastomosis, Hartmann's procedure
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele Roma
Perforated Diverticulitis
Characteristics of Abdominal Fluid in Patients With Diverticulitis Hinchey III or IV
Perforated diverticulitis of the colon can be complicated by peritonitis, either purulent or fecal. Both are life threatening conditions requiring emergency surgery.
- Trial name
- NCT04427891
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Appendicitis With Peritonitis
Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)
Appendicitis is a common pathology and the one of the most common surgical procedures performed in France. Young subjects are the most frequent patients with appendicitis.
- Trial name
- NCT05854914
- Testing
- Use of hypnosis videos
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice