Clinical trials: Peritonitis
Spontaneous Bacterial Peritonitis
Rifaximin for the Secondary Prevention of Spontaneous Bacterial Peritonitis Recurrence in Cirrhotic Patients
The aim of this study is to evaluate whether long-term rifaximin administration reduces spontaneous bacterial peritonitis recurrence rate in cirrhotic patients.
- Trial name
- NCT02011841
- Testing
- Rifaximin, Ciprofloxacin
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Chronic Peritoneal Dialysis
Method of Exit Site Care in Chronic Peritoneal Dialysis Patients
Peritoneal dialysis accounts for more than 70% of the dialysis modality in Hong Kong. Exit site infection (ESI) is one of the causes leading to peritoneal catheter removal. Appropriate exit-site care can prevent ESI.
- Trial name
- NCT00416338
- Testing
- film dressing by adhesive
- Where
- Hong Kong
- Volunteers
- 11 people
- Sponsor
- Chinese University of Hong Kong
Microbial Colonization, Bacterial Peritonitis
FEcal Transplant, a Hope to Eradicate Colonization of Patient Harboring eXtreme Drug Resistant Bacteria?
Our trial try to eradicate digestive tract colonization of patient harboring Extreme Drug Resistant (XDR) bacteria by performing a fecal transplantation.
- Conditions
- Microbial Colonization, Bacterial Peritonitis, Faeces Smearing
- Trial name
- FEDEX (NCT03029078)
- Testing
- fecal microbiota transplant
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Peritoneal Dialysis-related Infection
Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection
Peritoneal dialysis-related infection is a complication that leads to peritoneal dialysis catheter removal or patient death. The present study aimed to investigate peritoneal dialysis-related infection, causative pathogens…
- Trial name
- NCT05251584
- Testing
- Mupirocin, Gentamicin
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis
Targeted Education ApproaCH to Improve Peritoneal Dialysis Outcomes Trial
For many patients peritoneal dialysis (PD) is the preferred form of dialysis to treat kidney disease as it provides greater flexibility and the ability to dialyse at home.
- Conditions
- Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis, Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel Infection
- Trial name
- TEACH-PD (NCT03816111)
- Testing
- TEACH-PD Training Curriculum, Current standard PD training
- Where
- 48 sites in Australia, New Zealand
- Volunteers
- 1,462 people
- Sponsor
- The University of Queensland
Candida Sepsis, Candidiasis, Invasive
Early Identification of Candida in Intra-abdominal Candidiasis
Intra-abdominal candidiasis remains the first origin of invasive candidiasis in critically ill patients with a mortality up to 60%. This high mortality is partly related to delay of anti-fungal treatment administration.
- Conditions
- Candida Sepsis, Candidiasis, Invasive, Peritonitis Infectious, Critically Ill
- Trial name
- ICCA (NCT05264571)
- Testing
- calscreener, Metabolic profile, optical microscopy
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Spontaneous Bacterial Peritonitis
A Randomized Controlled Trial Comparing Imipenem and Tigecycline Versus Imipenem and Tigecycline With GM-CSF for the Management of Spontaneous Bacterial Peritonitis Presenting With Septic Shock.
Study population: A total of 90 consecutive patients of decompensated cirrhosis of any etiology, presenting to the Institute of Liver and Biliary Sciences with SBP with septic shock will be included.
- Trial name
- NCT04208763
- Testing
- Imipenem, Tigecycline, GMCSF
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Peritonitis
Pedicled Seromuscular Flap For Enforcement Of High Risk Intestinal Anastomoses
This is a control matched prospective study evaluating the use of seromuscular flap for high risk anastomoses.
- Trial name
- NCT01391169
- Testing
- seromuscular flap enforcement
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bacterial Infections and Mycoses, Appendicitis
Doripenem in the Treatment of Complicated Intra-Abdominal Infections
The purpose of this study is to compare the clinical response rate of doripenem versus a comparator in the treatment of hospitalized patients with complicated intra-abdominal infections.
- Conditions
- Bacterial Infections and Mycoses, Appendicitis, Cholecystitis, Pancreatitis
- Trial name
- NCT00229060
- Testing
- doripenem
- Volunteers
- 483 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Spontaneous Bacterial Peritonitis
A Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a common and frequently fatal complication of end-stage liver disease with a mortality of up to 10% primarily due to the development of kidney failure.
- Trial name
- NCT02528097
- Testing
- Standard Care, Experimental
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- NYU Langone Health
Spontaneous Bacterial Peritonitis
Prediction of SBP in Cirrhotic Patients by Platlet Count, Na and AlBl Index.
This study aims to evaluate whether integrating serum sodium levels and platelet count with the Albumin-Bilirubin (ALBI) score can improve the early prediction of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with…
- Trial name
- NCT07116369
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Peritonitis
Point-of-care Test for Diagnosis of Peritonitis in Peritoneal Dialysis Patients
Peritoneal dialysis (PD) is a home-based dialysis therapy and peritonitis is a serious complication in PD. A reliable point-of-care test to detect peritonitis is important for patients to self-detect peritonitis at home as…
- Trial name
- Periplex (NCT04070196)
- Testing
- Periplex
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore General Hospital
Cirrhosis
Intravenous Ciprofloxacin Versus Intravenous Ceftriaxone: Spontaneous Bacterial Peritonitis in Cirrhosis of Liver
Spontaneous bacterial peritonitis (SBP) is one of the leading causes of morbidity and mortality in patients with cirrhosis. Spontaneous bacterial peritonitis (SBP) is a common bacterial infection in patients with cirrhosis and…
- Trial name
- NCT07552870
- Testing
- intravenous ciprofloxacin, intravenous ceftriaxone
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- Shahida Islam Medical Complex
Spontanous Fungal Peritonitis
Risk Factors of Spontaneous Fungal Peritonitis in Cirrhotic Patients
Spontaneous bacterial peritonitis (SBP) is an infection of the peritoneal cavity with no surgically treatable intra-abdominal source of infection.
- Trial name
- NCT05117073
- Testing
- ASCITIC FLUID CULTURE
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Abdominal Sepsis, Abdominal Infection
Closed or Open Abdomen for the Management of Abdominal Sepsis
This is a prospective randomized clinical study. The study will comprise the randomized decision to either A) primarily close the fascia after laparotomy for intra-abdominal infection (CLOSED); or B) leave the fascia open after…
- Trial name
- NCT03163095
- Testing
- Open Abdomen Management with ANPPT dressing, Closed Abdomen Management
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- University of Calgary
Intra-Abdominal Infection, Candida
Diagnostic Performance of the CandID PLUS PCR for the Diagnosis of Intra-abdominal Candidiasis in Critically Ill Patients
Invasive candidiasis are the most common form of fungal infection in critically ill patients, particularly intra-abdominal candidiasis (IAC), which is associated with high morbidity and mortality.
- Conditions
- Intra-Abdominal Infection, Candida, Peritonitis Infectious, Molecular Diagnostic
- Trial name
- CANDIDIAG (NCT07005258)
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Central Hospital, Nancy, France
Primary Bacterial Peritonitis
Identification of Ascitic Fluid Bacterial Pathogens in Spontaneous Bacterial Peritonitis
Several studies have pointed out changes in the epidemiology of the causative bacteria in SBP and bacterascites and in their susceptibility to antibiotics.
- Trial name
- NCT02463721
- Testing
- ascitic fluid culture and microbiological testing
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Infection
Assessment of the Safety and Efficacy of Ciproxan-I.V. in Daily Clinical Practice - Analysis Results From a Post-marketing Surveillance
This study is a post-marketing surveillance in Japan, and it is a local prospective and observational study of patients who have received Ciproxan intravenously as a first-line treatment for sepsis, secondary skin infections…
- Trial name
- NCT01670435
- Testing
- Ciprofloxacin (BAYQ3939)
- Where
- Japan
- Volunteers
- 3,274 people
- Sponsor
- Bayer
Spontaneous Bacterial Peritonitis
To Compare the Efficacy of Carbepenem Versus Carbepenem Plus GM-CSF in Difficult To Treat Spontaneous Bacterial Peritonitis
A Minimum of 150 consecutive patients of decompensated cirrhosis of any etiology, presenting to the Institute of Liver and Biliary Sciences hospital with a diagnosis of difficult to treat SBP will be included and randomized into…
- Trial name
- NCT02468089
- Testing
- Carbepenem, Albumin, GMCSF (of Granulocyte-Monocyte Colony-Stimulating Factor) .
- Where
- India
- Volunteers
- 146 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Peritonitis
Change Trend of Effluent Eosinophil During Peritoneal Dialysis-Related Peritonitis
A multi-center prospective cohort study will be conducted to explore the change trend of eosinophil in peritoneal dialysis effluent during peritoneal dialysis-associated peritonitis, and to explore the relationship between…
- Trial name
- NCT04594421
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital