Clinical trials: Periprosthetic Fractures
Femoral Neck Fractures, Periprosthetic Fractures
Postoperative Periprosthetic Fractures in Hip Fracture Patients: Exeter vs Anatomic SP2 Lubinus Stem
Recent studies have indicated a high incidence of postoperative periprosthetic femoral fracture in elderly patients treated with two commonly used cemented polished, tapered femoral stems.
- Trial name
- PPFEvL (NCT03326271)
- Testing
- Exeter stem, Lubinus SP2 stem
- Volunteers
- 2,527 people
- Sponsor
- Sundsvall Hospital
Revision Total Hip Arthroplasty, Periprosthetic Fracture of Hip
Prospective Follow-up of the Prevision Hip Stem With Comparison of Different Implant Variants
The study design is confirmative for non-inferiority of the functional outcome of the implants and is intended to examine the safety and performance of the Prevision hip stem.
- Trial name
- PREMO (NCT06626490)
- Testing
- Prevision Revision hip endoprosthesis stem implantation
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 120 people
- Sponsor
- Aesculap AG
Periprosthetic Fractures
Locking Compression Plate Fixation Versus Revision- Prosthesis of Vancouver-B2, B3 and C Periprosthetic Femoral Fractures After Total Hip Replacement
The purpose of this study was to compare the clinical (range of motion, weight bearing, quality of life) and radiographic outcome (boney consolidation) between open reduction and internal fixation using locking compression plates…
- Trial name
- NCT02391129
- Testing
- Operation for Periprosthetic fractures of the hip with stem loosening
- Volunteers
- 102 people
- Sponsor
- Medical University of Vienna
Distal Femur Fracture, Periprosthetic Fractures
Safety and Performance of the Biphasic Plate Distal Femur: A Multicenter Case Series
The goal of this observational multicenter case series is to assess the safety and performance of the CE-marked "Biphasic Plate Distal Femur" during standard of care.
- Conditions
- Distal Femur Fracture, Periprosthetic Fractures, Intra-Articular Fractures, Supracondylar Fracture
- Trial name
- NCT06028971
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 60 people
- Sponsor
- 41medical AG
Periprosthetic Fractures, Distal Femur Fractures
Periprosthetic Distal Femur Fracture
A periprosthetic distal femur fracture is a fracture close to a knee implant. This type of fracture is often difficult to fix because of the close proximity of the two surgical implants which can sometimes interfere with proper…
- Trial name
- NCT01973712
- Testing
- Locked Compression Plating, Retrograde Intramedullary Nailing (RIMN)
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Unity Health Toronto
Distal Femur Fracture
Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)
Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence.
- Trial name
- NCT05792189
- Testing
- Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Femoral Neck Fractures, Bone Density
Radiostereometric Analysis of Acetabular Wear and Periprosthetic Bone Mineral Density Changes in Hemiarthroplasties
Substudy and continuation of HEMI-SAB-UUS (NCT00491673) Study on radiostereometric measurements of acetabular wear in bipolar hemiarthroplasties and measurements of periprosthetic bone mineral density in cemented and uncemented…
- Conditions
- Femoral Neck Fractures, Bone Density, Acetabular Wear, Hemiarthroplasty
- Trial name
- HEMI-RSADEXA (NCT00607516)
- Testing
- Cemented primary bipolar hemiarthroplasty of the hip, Uncemented primary bipolar hemiarthroplasty of the hip
- Where
- Norway
- Volunteers
- 22 people
- Sponsor
- Ullevaal University Hospital
Periprosthetic Fracture Around Prosthetic Joint Implant, Aseptic Loosening of Prosthetic Joint
Follow-Up of the Prevision® Hip Stem
The main objective of this study is to represent the treatment reality at the study site and to draw conclusions from cases of failure or suboptimal outcome.
- Trial name
- PRESPECT (NCT04833634)
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Aesculap AG
Aseptic Loosening, Infection
Maxx Orthopedics' PCK Revision TKA Study of Component Survivorship
The objectives of this clinical investigation are to evaluate the safety and performance of the Freedom Total Knee® PCK System.
- Conditions
- Aseptic Loosening, Infection, Bone Loss, MCL - Medial Collateral Ligament Rupture of the Knee
- Trial name
- NCT03312088
- Testing
- Freedom Knee PCK Components
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maxx Orthopedics Inc
Periprosthetic Fractures, Periprosthetic Fracture Around Prosthetic Joint Implant
Periprosthetic Fracture Registry (PPFx)
This registry supports international data collection and research on PPFx treatments after hip and knee arthroplasty. A registry such as this ultimately aims to provide far-reaching benefits to society including reduced morbidity…
- Trial name
- PPFx (NCT03378557)
- Where
- 13 sites in United States, Belgium and 4 more
- Volunteers
- 600 people
- Sponsor
- AO Innovation Translation Center
Femur Fractures
Types of Fixation of Vancouver B1 Periprosthetic Fractures
The purpose of this study is to compare two different but standard treatments for the fixation of Vancouver B1 periprosthetic. The investigators aim to compare open reduction internal fixation using a locked plating system versus…
- Trial name
- NCT01354535
- Testing
- Isolated Locked Compression Plate, Cable Plating and Strut Allograft with Cerclage Wiring
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- Unity Health Toronto
Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb
Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis
This study supports Spanish data collection and analysis on Periprosthetic and Peri-implant fractures of the upper and lower limb. Treatment and clinical management of this fractures are complex and goes along with complications.
- Conditions
- Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb, Periprosthetic Fractures, Peri-implant Fracture
- Trial name
- PIPPAS (NCT04663893)
- Where
- 7 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Femoral Neck Fracture, Infection
Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention
Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF).
- Trial name
- DAIR (NCT02771639)
- Testing
- Hip arthroplasty
- Volunteers
- 736 people
- Sponsor
- Sundsvall Hospital
Hip Fracture, Femoral Neck Fracture
Comparison of a Cemented, Polished Tapered Stem and an Anatomic Stem for Femoral Neck Fracture
Postoperative periprosthetic femoral fracture after hip arthroplasty is associated with considerable morbidity and mortality. Recent cohort studies have demonstrated a high incidence of PPF in elderly patients treated with two…
- Conditions
- Hip Fracture, Femoral Neck Fracture, Periprosthetic Femoral Fracture
- Trial name
- NCT02591342
- Volunteers
- 1,014 people
- Sponsor
- Sundsvall Hospital
Osteoarthritis, Arthritis
Periprosthetic Bone Mineral Density After Total Hip Arthroplasty Performed Through a Minimally Invasive Anterior Approach (AMIS) With Either an AMIStem or a Quadra Femoral Component
This is a monocentric, prospective, randomized clinical survey to verify if the periprosthetic remodelling brought about either the AMIStem or the Quadra femoral component is equivalent.
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head
- Trial name
- NCT01285843
- Testing
- Anterior Minimally Invasive Approach (AMIS)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Medacta International SA
Diphosphonates
Bisphosphonates Use After Total Joint Arthroplasty
Background Bisphosphonates has been associated with a decreased risk of revision total joint replacements because of its effects on decreased periprosthetic bone loss and prosthetic migration.
- Trial name
- NCT05623540
- Testing
- Bisphosphonates, Combinations
- Where
- Taiwan
- Volunteers
- 27,405 people
- Sponsor
- National Defense Medical Center, Taiwan
Distal Femur Fracture, Periprosthetic Fracture Around Prosthetic Joint Implant Knee
pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement
Periprosthetic distal femur fractures are a significant source of morbidity and mortality for elderly patients. One treatment option involved a surgical fixation with plates or nails, screws and cables/wires along the side of…
- Conditions
- Distal Femur Fracture, Periprosthetic Fracture Around Prosthetic Joint Implant Knee, Knee Fracture
- Trial name
- pDIFFIR (NCT05805774)
- Testing
- Distal Femur Replacement, Surgical fixation
- Where
- Canada
- Volunteers
- 148 people
- Sponsor
- Unity Health Toronto
Femoral Neck Fractures
Dual Mobility Cups in Hip Fracture Patients
Our aim is to develop a strategy that reduces the risk of dislocations after total hip arthroplasty surgery performed due to femoral neck fracture.
- Trial name
- DUALITY (NCT03909815)
- Testing
- Dual mobility cup, Standard cup
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 1,600 people
- Sponsor
- Uppsala University
Periprosthetic Fracture Around Prosthetic Joint Implant Knee
Weight-Bearing CT Periprosthetic Distal Knee Fractures
Total knee arthroplasty (TKA), a knee implant surgery, is a treatment for end-stage knee osteoarthritis. In some cases, patients suffer an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA…
- Trial name
- NCT06525610
- Testing
- Periprosthetic Fracture Knee Repaired CT Scans
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteonecrosis, Femoral Neck Fracture
A Comparison of Two Different Surgical Techniques in Hip Resurfacing Arthroplasty
The purpose of the study is to compare two different surgical techniques in hip resurfacing arthroplasty (RHA), comparing bloodflow and metabolism in the femoral head, as well as implant migration, periprosthetic bone mineral…
- Conditions
- Osteonecrosis, Femoral Neck Fracture, Implant Failure
- Trial name
- NCT00913679
- Testing
- Surgical approach (ReCap Hip Resurfacing System)
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- University of Aarhus