Clinical trials: Perioperative Risk Assessment
Risk
Remembering Risk: Using Visual Risk Display of MINS to Obtain Informed Consent to Undergo Elective Surgery
Disclosure of anticipated risks to individuals considering undergoing an operative procedure is an important aspect of informed consent process.
- Trial name
- NCT04247841
- Testing
- Visual Aid, Scripted Risk Discussion
- Where
- Canada
- Volunteers
- 456 people
- Sponsor
- Dr. Michael McMullen
ASA Class III/IV Patients, Surgery
Artificial Intelligence-augmented Perioperative Clinical Decision Support
The study investigates a novel anaesthesiological clinical decision support (CDS) application, that integrates risk evaluation tools and updated clinical guidelines guided by artificial intelligence in the setting of preoperative…
- Conditions
- ASA Class III/IV Patients, Surgery, Clinical Decision Support Systems
- Trial name
- KIPeriOP (NCT05284227)
- Testing
- Electronic Clinical Decision Support Application
- Where
- Germany
- Volunteers
- 210 people
- Sponsor
- Wuerzburg University Hospital
Postoperative Delirium (POD)
Validation of a Risk Assessment Model for Postoperative Delirium Based on Artificial Intelligence
Postoperative delirium (POD) is a frequent postoperative complication in the elderly, characterised by fluctuating disturbances in attention, awareness, and cognition.
- Trial name
- NCT05639348
- Testing
- Data collection on POD for calculation of the PIPRA score
- Where
- 3 sites in Switzerland
- Volunteers
- 993 people
- Sponsor
- University Hospital, Basel, Switzerland
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Postoperative Intensive Care Unit Admission, Perioperative Risk Assessment
Pilot Study of Anesthesiologists' Preoperative Prediction of Postoperative Intensive Care Unit Admission
This prospective observational pilot study will evaluate how accurately anesthesiologists can predict, before a procedure, whether an adult patient will require admission to an intensive care unit (İCU) after surgery or an…
- Trial name
- NCT07780526
- Testing
- Preoperative Clinical Prediction of Postoperative ICU Admission
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Van Training and Research Hospital
Perioperative Complications
Establishment of a Predictive System for Perioperative Risk Assessment and Electronic Flowcharting Response Strategies in Thoracic Surgery
1. To establish a risk assessment scale for thoracic surgery for the Chinese population, and to classify patients; risk according to the relevant scale; 2.
- Trial name
- NCT06566053
- Testing
- Observation
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Hengxing Liang
Perioperative/Postoperative Complications
Preoperative Laboratory Parameters and Scorings Systems on Postoperative Pulmonary Complications in Thoracic Surgery
Postoperative pulmonary complications (PPC) emerge as a major risk that determines the morbidity and mortality of patients after surgery. PPCs affect the length of hospital stay and increase health costs.
- Trial name
- NCT04995939
- Testing
- Laboratory parameters and Scoring systems
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Liver Failure, Acute
Perioperative Lactate Kinetics in Patient Undergoing Major Liver Surgery
Major liver surgery is associated with increased incidence of perioperative complications and increased mortality if these are not addressed quickly in a high dependency intensive care unit.
- Trial name
- NCT04512014
- Testing
- serum lactate
- Where
- Romania
- Volunteers
- 55 people
- Sponsor
- Institutul Clinic Fundeni
Perioperative Cardiac Complications
Perioperative Cardiac Complications in Noncardiac Surgery in Tibet, China
This observational study will describe the incidence and risk factors of perioperative cardiac complications (PCCs) in patients undergoing non-cardiac surgery in Tibet Autonomous Region.
- Trial name
- NCT04819698
- Testing
- Troponin I (cTnI ) monitoring
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Complications
Personalized Hemodynamic Therapy in Patients Undergoing High-risk Surgery
The purpose of this study is to evaluate the effectiveness of using the personal preoperatively assessed cardiac output in high-risk patients to guide perioperative administration of fluids and vasoactive drugs on predefined…
- Trial name
- TAPIR (NCT02834377)
- Testing
- Treatment algorithm targeting individual cardiac output
- Where
- Germany
- Volunteers
- 188 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Surgery--Complications
Continuously Iterative Perioperative Holistic Evaluation of Risk and Hypotension Prediction Index
The investigators would like to explore whether Hypotension Prediction Index during and immediately after surgery can be used to improve the accuracy of scores that predict postoperative problems.
- Trial name
- CIPHER-HPI (NCT04807036)
- Testing
- Hypotension Prediction Index
- Volunteers
- 150 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Social Deprivation
Social Deprivation and Postoperative Mortality
Socioeconomic factors are associated with differences in health outcomes, but their impact on surgical patients is still not well understood, especially in low- and middle-income countries.
- Trial name
- NCT07621211
- Where
- 7 sites in Brazil
- Volunteers
- 45,000 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pediatric Surgical Patients
Evaluation of Preoperative Risk Factors in Children
This study aimed to evaluate preoperative risk factors in pediatric patients and to determine their effectiveness in predicting intensive care unit admission within 72 hours.
- Trial name
- NCT05852899
- Where
- Turkey (Türkiye)
- Volunteers
- 326 people
- Sponsor
- Istanbul University - Cerrahpasa
Telemedicine, Anesthesia
Anesthetic and Perioperative Risk Assessment Before Programmed Surgery: Anesthetic Teleconsultation Versus Face-to-face Anesthesia Consultation.
The anesthesia safety decree made it compulsory in 1994 to carry out a pre-anesthesia consultation before any operative or interventional act.
- Conditions
- Telemedicine, Anesthesia, Consultation, Remote
- Trial name
- TELANESTH (NCT04920604)
- Testing
- Face-to-face anesthesia consultation, Remote anesthesia consultation
- Where
- France
- Volunteers
- 172 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Atrial Fibrillation (AF), VTE
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure
PAUSE 2 study is a prospective, open-label, blinded-endpoint non-inferiority RCT of PAUSE vs. ASRA management in DOAC treated high risk patients with AF/VTE who need elective high bleed risk surgery/procedure and/or any procedure…
- Trial name
- PAUSE 2 RCT (NCT06957366)
- Testing
- PAUSE Perioperative DOAC Management, ASRA Perioperative DOAC Management
- Where
- 14 sites in United States, Belgium and 2 more
- Volunteers
- 920 people
- Sponsor
- McMaster University
Preoperative Care
Prospective Validation of an Artificial Intelligence Tool for Pre-Anesthetic Assessment
This prospective observational cohort study aims to validate an artificial intelligence (AI) tool designed for pre-anesthetic assessment in Portuguese, tailored to the Brazilian healthcare context.
- Trial name
- NCT07290647
- Testing
- AI-based pre-anesthetic assessment, Anesthesiologist-led pre-anesthetic evaluation
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Individuality, Perioperative/Postoperative Complications
Perioperative Heart Rate Variability Analysis in Realtime
This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent…
- Conditions
- Individuality, Perioperative/Postoperative Complications, Heart Rate and Rhythm Disorders, Surgical Complications From General Anesthesia
- Trial name
- PHERVR (NCT02761031)
- Where
- Austria
- Volunteers
- 88 people
- Sponsor
- Medical University of Vienna
Perioperative Risk Assessment
Frailty Assessment Reveals Cognitive Differences in ASA Classification: Anesthesiologists vs Large Language Models
The American Society of Anesthesiologists (ASA) Physical Status Classification System is widely used to assess perioperative risk, but it does not explicitly include frailty as a standardized variable.
- Trial name
- ASA-AI (NCT07399938)
- Testing
- Observational Assessment Only
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anesthesiological Risk Reduction, Intensive Care Risk Reduction
Identification of Outcome Relevant Indicators in Routine Data
The availability of electronic documentation systems in patient care means that large amounts of clinical routine data are available from which conclusions can be drawn for improving patient care.
- Trial name
- NCT04670744
- Where
- Germany
- Volunteers
- 1,000,000 people
- Sponsor
- Charite University, Berlin, Germany
Hemodynamic Monitoring
Evaluation of Clinical Impact of Non-Invasive Hemodynamic Monitoring to Optimize Perioperative Care
This project is designed to assess the impact of pre-operative use of non-invasive hemodynamic monitoring technologies on improving peri-operative and post-operative care of moderate to high-risk surgical patients with poor…
- Trial name
- NCT02950649
- Testing
- invasive Hemodynamic monitoring via Clearsight/Nexfin Systems from Edwards Lifesciences, No Hemodynamic Monitored Guided Assesment
- Where
- 3 sites in United States
- Volunteers
- 189 people
- Sponsor
- Loma Linda University