Clinical trials: Perioperative Care
Anxiety State, Satisfaction
Immersive Virtual Reality Exposure for Reducing Preoperative Anxiety in Children
Perioperative anxiety management for children undergoing surgery poses a major challenge to anaesthesiologists as high anxiety, reported in numerous studies, leads to detrimental effects physiologically, mentally and on pain…
- Conditions
- Anxiety State, Satisfaction, Compliance
- Trial name
- NCT07018999
- Testing
- Immersive virtual reality operating theatre tour
- Where
- Hong Kong
- Volunteers
- 114 people
- Sponsor
- Hong Kong Children's Hospital
Cardiac Output
Impedance Cardiography: Clinical Evaluation of Endotracheal Cardiac Output Monitor (ECOM)
1. Compare measurements of cardiac output derived from electrical measurements from electrodes on an endotracheal tube (ECOM or Endotracheal Cardiac Output Monitor) to those made from a pulmonary artery thermodilution catheter.
- Trial name
- ECOM (NCT00924482)
- Testing
- Placed ECOM endotracheal cardiac output monitor in patients undergoing cardiac surgery
- Volunteers
- 261 people
- Sponsor
- University of California, San Francisco
Hypothermia
Pre-warming Prevents Hypothermia in Elective Cesarean Section
Background: Hypothermia is common during general and regional anesthesia even when active warming measures are taken. The existing literature shows that, in pregnant patients, the use of forced air-warming during cesarean section…
- Trial name
- hypothermia (NCT02091466)
- Testing
- pre-warming
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Reduction of Length of Hospitality Stay, Reduction of Perioperative Complications
GDT by Cardiac Index Trending Via a Radial Arterial Line in General Surgery
This is a multi-Center, prospective, randomized Outcome Study comparing continuous cardiac index trending via a radial arterial line versus standard care in general surgical patients
- Trial name
- NCT01401283
- Testing
- measurement of cardiac output and pulse pressure variation
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Goal Directed Therapy, Fluid Therapy
Goal Directed Therapy Versus Standard Care in Lung Resection Surgery (GDT-thorax Study).
The primary aim of this study is to quantify and compare the hemodynamic control of cardiac index in patients who receive either goal-directed therapy or standard hemodynamic management in lung resection surgery
- Trial name
- GDT-thorax (NCT03245372)
- Testing
- Standard care, Goal directed therapy
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Hypertension
Perioperative Blood Pressures and Chronic Hypertension
This study aims to assess the performance of presurgical clinic blood pressure measurements in predicting home blood pressure readings among surgical patients.
- Trial name
- NCT02136810
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Staphylococcus Aureus, Health Care Associated Infection
Reducing Perioperative S. Aureus Transmission
The purpose of this study is to prevent the spread of S. aureus, a dangerous bacterium, within the operating room and between patients undergoing surgery.
- Conditions
- Staphylococcus Aureus, Health Care Associated Infection, Health Care Worker Patient Transmission
- Trial name
- NCT03638947
- Testing
- Swab and decolonization using povidone-iodine cleansing
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Randy Loftus
Orthopedic Surgery, Older Adults
Perioperative Mental Health in Orthopedic Surgery
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing Orthopedic surgery…
- Conditions
- Orthopedic Surgery, Older Adults, Depression, Anxiety
- Trial name
- CPMH (NCT05697835)
- Testing
- Behavioral activation, Medication optimzation, Care as usual
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Washington University School of Medicine
Cancer
Utilizing Advance Care Planning Videos to Empower Perioperative Cancer Patients and Families
Through close engagement with our patient and family member co-investigators, the investigators have developed a video-based advance care planning aid for cancer patients and their family members who are preparing for major…
- Trial name
- ACPvideo (NCT02489799)
- Testing
- Advance care planning video, Control video
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Anesthesia
Survey to Identify Substance Use in Teenagers and Adolescents
This is a prospective survey study of patients 12-21 years undergoing anesthetic care. The primary objective is to determine the incidence of illicit substance use and abuse prior to anesthetic care.
- Trial name
- NCT05353036
- Testing
- Survey
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Nationwide Children's Hospital
Acupuncture, Ear
Battlefield Acupuncture and Its Use In Multimodal Perioperative Anesthesia Care
The study hypothesis is that perioperative Auricular (battlefield) acupuncture for general surgery and urology cases undergoing general anesthesia will decrease opioid requirements, postoperative pain, the incidence of PONV, and…
- Trial name
- BFA (NCT04615299)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Surgery, Surgery--Complications
Telemedicine Control Tower for the Operating Room: Navigating Information, Care and Safety
Medical errors account for thousands of potentially preventable deaths each year. With the annual increase of surgical cases there is a need for research into the potential utility of a telemedicine-based control center for the…
- Conditions
- Surgery, Surgery--Complications, Perioperative/Postoperative Complications
- Trial name
- TECTONICS (NCT03923699)
- Testing
- Anesthesia Control Tower monitoring
- Where
- United States
- Volunteers
- 79,560 people
- Sponsor
- Washington University School of Medicine
Gastrointestinal Cancer
Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members
The study goal is to compare surgeon-palliative care team co-management, versus surgeon alone management, of patients and family members preparing for major upper gastrointestinal cancer surgery.
- Trial name
- PERIOP-PC (NCT03611309)
- Testing
- Surgeon-palliative care team co management, Surgeon team alone management
- Where
- 5 sites in United States
- Volunteers
- 379 people
- Sponsor
- Stanford University
Pain, Perioperative
Study To Investigate The Effectiveness Of Pregabalin For Management Of Patients Undergoing Total Hip Replacement
The purpose of this study is the investigate if pregabalin started a day before surgery and continued for 14 days post-operatively can reduce post-operative pain, relieve pre- and post-operative anxiety and sleep disturbances.
- Trial name
- NCT00905437
- Testing
- Pregabalin
- Where
- 7 sites in India
- Volunteers
- 72 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Cancer
Automated Geriatric Co-Management Program in Older Patients With Solid Mass or Nodule Suspicious for Cancer
The purpose of this study is to find out if it is possible to use the automated geriatric co-management program to manage the participants care before, during and after surgery.
- Trial name
- NCT03885908
- Testing
- in-person geriatric co-management, automated geriatric co-management
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Allergy Drug, Allergic Reaction
Preoperative Survey to Evaluate Patient Allergy
The study will only involve identification of the listed allergies from the electronic medical record and investigation into the symptoms that prompted this allergy listing.
- Conditions
- Allergy Drug, Allergic Reaction, Pediatric, Surgery
- Trial name
- NCT05670756
- Testing
- Survey
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Nationwide Children's Hospital
Malignant Digestive System Neoplasm
Perioperative Telemonitoring to Optimize Cancer Care and Outcomes
This study aims to see whether an at-home monitoring program that collects health, symptoms, and quality of life data in real-time can be included as part of the care of surgery patients in order to provide better recovery.
- Trial name
- NCT04986566
- Testing
- Best Practice, Health Education, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- City of Hope Medical Center
Pelvic Floor Disorders
Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation
Currently, perioperative pelvic floor physical therapy (PFPT) is not standard of care for all patients who undergo vaginoplasty surgery.
- Trial name
- FLOWER (NCT05690555)
- Testing
- Preoperative and Postoperative Pelvic Floor Physical Therapy (PFPT), No Pelvic Floor Physical Therapy (PFPT), Postoperative PFPT
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- The Cleveland Clinic
Perioperative Optimization
Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data
This REMAP Periop ERP domain study falls under the Periop Core Protocol, which compares the different recommended strategies for enhancing recovery through the use of various standard of care treatments before, during and after…
- Trial name
- NCT04606264
- Testing
- Neuraxial Analgesia, Regional Block 1: Paravertebral, Perphenazine
- Where
- 3 sites in United States
- Volunteers
- 3,395 people
- Sponsor
- Jennifer Holder-Murray
Alzheimers Disease, Postoperative Delirium
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal…
- Conditions
- Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
- Trial name
- MADCO-PC (NCT01993836)
- Testing
- Total intravenous anesthesia with propofol, General anesthesia with isoflurane
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Duke University