Clinical trials: Periodontal Health
Peri-implantitis, Peri-Implant Health
Reconstructive Therapy for Peri-implantitis Using Tuberosity Bone with or Without Electrolytic Cleaning: a Randomized Clinical Trial
This study aims to evaluate the effectiveness of two surgical approaches for managing peri-implantitis, a condition characterized by inflammation and bone loss around dental implants.
- Conditions
- Peri-implantitis, Peri-Implant Health, Peri-Implantational Loss, Peri-Implantation Loss
- Trial name
- NCT06708247
- Testing
- Standard Peri-implant Reconstructive Surgery, Electrolytic Cleaning with Peri-implant Reconstructive Surgery
- Where
- Lithuania
- Volunteers
- 31 people
- Sponsor
- Vilniaus Implantologijos Centro (VIC) Klinika
Peri-Implantitis, Periodontitis
Macrophage Markers in Periodontal and Peri-implant Health and Disease
Macrophage surface markers (CD80, CD163 and CD206) will be evaluated in periodontally healthy gingiva, healthy peri-implant mucosa, and periodontitis and peri-implantitis lesions.
- Trial name
- NCT05242354
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontitis
The Influence of Porcelain Fused to Metal ( PFM) and Zirconia Crowns on Periodontal Health
Investigate the influence of the crown tye Porcelain fused to metal or Zirconia on periodontal health.
- Trial name
- NCT02461823
- Testing
- Zirconia crown, Porcelain metal crown
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Gingival Margin Elevation
Effect of Different Base Materials on Ginigiva During Gingival Margin Elevation
This study will be conducted to investigate 1. The effect of deep margin elevation with different base materials (resin modified glass ionomer, flowable composite, injectable hybrid composite) on fracture resistance and marginal…
- Trial name
- NCT06944080
- Testing
- base material(Tetric® N-Flow,Beautifil-Flow PLUS,GC fuji II LC capsule)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Minia University
Gingivitis, Gingivitis; Chronic
A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students
This multicentre randomised controlled trial aims to evaluate the efficacy and safety of the SMILETM (Siwak Method for Integrated Lifestyle Enhancement) module in improving short-term periodontal outcomes, oral hygiene behaviour…
- Trial name
- SMILE (NCT07702383)
- Testing
- SMILE Module, Conventional Toothbrushing Module
- Where
- 4 sites in Malaysia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Chronic Periodontitis, Aggressive Periodontitis
Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease
Subjects were selected from the outpatient clinic, Department of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Cairo University.
- Trial name
- NCT03128502
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pregnancy Related, Dental Caries
The Effects of Pregnancy on Oral Health
The aim of this study was to evaluate the effects of pregnancy on salivary pH, flow rate, caries experience and periodontal status.
- Conditions
- Pregnancy Related, Dental Caries, Periodontal Diseases, Saliva Altered
- Trial name
- NCT06343337
- Testing
- Evaluation of DMFT index, CPI scores, salivary pH and flow rate in pregnant and non-pregnant woman
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronical Periodontitis, Ratio of P. Gingivalis and S. Cristatus
Intense Education of Periodontal Health Maintenance
Investigators hypothesize that good oral hygiene may inhibit P. gingivalis, a keystone periodontal pathogen, entering mature dental plaque, which leads to a higher ratio of S. cristatus and P. gingivalis.
- Trial name
- NCT03610607
- Testing
- Intense education
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Meharry Medical College
Periodontal Disease, Chronic Kidney Disease
The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed Patients
Several studies revealed a direct relationship between the severity of periodontal inflammation and CRP (NHANES III, Dumitriu HT et al, 1998).
- Trial name
- PAROHEM (NCT01785355)
- Testing
- Dental treatment
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- Anemia Working Group Romania
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and…
- Trial name
- NCT07255040
- Testing
- Test Dentifrice, Parodontax Complete Protection, Colgate Cavity Protection
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- HALEON
Peri-Implantitis and Peri-implant Mucositis
Peri-implant Vitamin D and Cathelicidin (LL-37) Levels
This research aims to explore the influence of vitamin D on the body's defense system by examining its impact on specific proteins involved in immune response and inflammation in the soft tissues surrounding dental implants.
- Trial name
- NCT06867250
- Testing
- The patients' periodontal clinical parameters were recorded. PISF samples were collected, and the evaluations of 25(OH)D and LL-37 were conducted using enzyme-linked immunosorbent assay.
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Association of Coffee Consumption With Peri-Implant Status
A total of 123 participants (291 implants) applying to Bolu Abant İzzet Baysal University will be included in the study. Based on anamnesis, radiographic examination, and the 2018 classification of periodontal diseases, the…
- Trial name
- ACCPS (NCT07747558)
- Testing
- Coffee
- Where
- Turkey (Türkiye)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Tuğba ŞAHİN
Periodontitis, Gingivitis and Periodontal Diseases
Salivary Free Amino Acid Profiles in Periodontitis: Associations With Clinical Parameters and Dynamic Responses to Non Surgical Therapy
# Brief Summary (Word count: 198) This combined observational and interventional study investigates salivary amino acid profiles and their connections to periodontal conditions, as well as how these substances change after…
- Conditions
- Periodontitis, Gingivitis and Periodontal Diseases, Periodontal Debridement, Periodontal Attachment Loss
- Trial name
- FAA-CP-SRP (NCT07669233)
- Testing
- Non-surgical periodontal therapy
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zhang, Yuwei
Post COVID-19 Condition
Periodontal Health in Post COVID-19 Patients
The aim of this study is; To Assess the association between periodontal health and Matrix metalloproteinase-8 (MMP-8) level in Gingival Crevicular Fluid (GCF) in post COVID-19 patients.
- Trial name
- NCT05950230
- Testing
- Assess Periodontal Health Status, Collecte GCF samples by paperstrip
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Dental Implants, Aggressive Periodontitis
Impact of Periodontitis Grading on Peri-Implant Clinical and Bone Health: A 60-Month Prospective Study
This prospective cohort study evaluated the effect of periodontitis grading on peri-implant clinical and radiographic outcomes over a 60-month follow-up.
- Conditions
- Dental Implants, Aggressive Periodontitis, Chronic Periodontitis, Staging
- Trial name
- NCT07671456
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Health, Space Maintainer
Evaluation of Band-Loop Space Maintainers Produced With Three-Dimensional Printer and Conventional Technique
Our research is planned as a randomised clinical trial. The main aim of our study is to evaluate the clinical success of band and loop space maintainers produced by three-dimensional printer and conventional technique and the…
- Conditions
- Dental Health, Space Maintainer, Pediatric Dentistry, 3D Printing
- Trial name
- NCT06798090
- Testing
- Band and Loop Space Maintainer Produced with Three-Dimensional Printer, Band and Loop Space Maintainer Produced with Conventional Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Aydin Adnan Menderes University
Inflammatory Bowel Diseases, Periodontitis
Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD)
IBD patients have a higher risk of oral diseases that affect the oral mucosa, the teeth and the tooth supporting tissues. These conditions are often associated with pain, bleeding and impaired masticatory function which may have…
- Conditions
- Inflammatory Bowel Diseases, Periodontitis, Dental Caries, Tooth Loss
- Trial name
- OQal-MICI (NCT05096897)
- Testing
- Self-administrated questionnaires
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Gingivitis
Cervical Carious Lesions Restored With Calcium Silicate Based Cement (Biodentine) Compared With Glass-ionomer Cement
This study will test if applying calcium silicate cements (Biodentine) to restore cervical carious lesions might adversely affect the gingival health in comparison with conventionally used tooth colored material (GIC)
- Trial name
- NCT03418246
- Testing
- GIC, Biodentine
- Volunteers
- 28 people
- Sponsor
- Jordan University of Science and Technology
Type 2 Diabetes Mellitus, Periodontitis
Oral Health Policy for Patients With Type 2 Diabetes Mellitus in Chile: A Microsimulation Model Based on Real-world Data
The goal of this study is to evaluate the cost-effectiveness of the current proposal and different decision-making scenarios of periodontal care coverage increases for patients with T2DM in Chile.
- Conditions
- Type 2 Diabetes Mellitus, Periodontitis, Diabetic Complication, Dental Care
- Trial name
- NCT05809817
- Testing
- Periodontal treatment
- Where
- 2 sites in Chile
- Volunteers
- 135 people
- Sponsor
- University of Chile