Clinical trials: Periodontal Disease, AVDC Stage 4
Periodontal Disease, AVDC Stage 3and 4, Epithelial Mesenchymal Transition
The Potential Association of Long Non-coding RNA (NEAT1 and MALAT1) in the Process of Epithelial-mesenchymal Transition in Periodontitis
Periodontitis is a polymicrobial, inflammatory condition affecting tooth-supporting tissues. It is characterized by a progressive loss of epithelial attachment and resorption of alveolar bone, which can lead to tooth loss.
- Conditions
- Periodontal Disease, AVDC Stage 3and 4, Epithelial Mesenchymal Transition, Long Noncoding RNA
- Trial name
- NCT05995067
- Testing
- periodontitis challenge
- Where
- Iraq
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ali A Abdulkareem
Periodontal Diseases, Periodontal Attachment Loss
Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment
The present study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to non-surgical periodontal treatment (NSPT) on the plasminogen-activating system in Stage 3-4, Grade C periodontitis patients.
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Periodontal Disease, AVDC Stage 3, Periodontal Inflammation
- Trial name
- NCT05233501
- Testing
- low level laser therapy, non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Periodontal Diseases, Periodontal Disease, AVDC Stage 3
Flapless Application of Enamel Matrix Derivative in Class II Mandibular Furcation Defects
Patients diagnosed with stage III or IV periodontitis that exhibit mandibular first or second molars with increased periodontal probing depth (PPD > 4 mm) and class II buccal mandibular furcation defects (horizontal probing depth…
- Conditions
- Periodontal Diseases, Periodontal Disease, AVDC Stage 3, Periodontal Disease, AVDC Stage 4, Furcation Defects
- Trial name
- NCT05541614
- Testing
- Emdogain® FL (flapless Emdogain®) - Enamel Matrix Derivative, Emdogain® - Enamel Matrix Derivative
- Where
- Greece
- Volunteers
- 44 people
- Sponsor
- Aristotle University Of Thessaloniki
Periodontal Disease, AVDC Stage 3, Periodontal Disease, AVDC Stage 4
Fasting-mimicking Diet and Periodontitis (FMD)
Periodontitis (gum disease) leads to the formation of gum pockets. Its treatment involves deep cleaning of the teeth, to remove soft and hard tooth deposits under the gum line.
- Conditions
- Periodontal Disease, AVDC Stage 3, Periodontal Disease, AVDC Stage 4, Periodontitis
- Trial name
- FMD (NCT06074861)
- Testing
- Fasting-mimicking diet + non-surgical periodontal therapy
- Where
- 5 sites in Spain
- Volunteers
- 28 people
- Sponsor
- Universitat Internacional de Catalunya
Tooth Extraction, Periapical Infections
Cortical Lamina for Alveolar Ridge Preservation
This randomized controlled clinical trial aims to evaluate the efficacy of placing a cortical lamina between the elevated flap and buccal bone plate following tooth extraction for preserving alveolar ridge dimensions.
- Conditions
- Tooth Extraction, Periapical Infections, Tooth Fracture, Periodontal Disease, AVDC Stage 4
- Trial name
- Lamina (NCT07231874)
- Testing
- Cortical Lamina Technique, Natural Healing (Control)
- Where
- Cuba
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy