Clinical trials: Periodic Breathing
Apnea of Prematurity, Preterm Infant
Detection of Respiratory Events Using Acoustic Monitoring in Extremely Preterm Infants
Extremely preterm infants, born before 29 weeks of pregnancy, often face breathing difficulties, also known as respiratory events, due to their undeveloped lungs and respiratory systems.
- Conditions
- Apnea of Prematurity, Preterm Infant, Periodic Breathing, Hypopnea
- Trial name
- DREAM 2 (NCT07552025)
- Testing
- Wireless acoustic sensor, Semi-structured interview, Nox T3s portable sleep monitoring device
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood.
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder
- Trial name
- NCT05656365
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Periodic Breathing
Different Loop Gain Phenotypes in Patients With Chronic Systolic Heart Failure and Periodic Breathing
Central sleep apnoea (CSA) is common in patients with chronic systolic heart failure (HFrEF). Various trials have shown a prevalence of 21 - 37% in this group of people.
- Trial name
- NCT03532412
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Apnea of Prematurity, Desaturation of Blood
Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants
This is a prospective crossover study to compare the within-subject effect of the two target ranges of arterial oxygen saturation (SpO2), both within the clinically recommended range of 90- 95%.
- Conditions
- Apnea of Prematurity, Desaturation of Blood, Central Apnea, Periodic Breathing
- Trial name
- NCT03695900
- Testing
- Targeting SpO2 at 93-95%, Targeting SpO2 at 90-92%
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Miami
Periodic Breathing, Cheyne-Stokes Respiration
Comparison of Modified With Conventional Adaptive Servoventilation Processes
The objective of this study is to compare the modified adaptive servoventilation control algorithm of the with the standardised algorithms of routinely-used servoventilation processes (AutoSet CS2) in terms of the effect on…
- Trial name
- NCT01037439
- Testing
- Adaptive Servo-controlled Ventilation (ASV)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- ResMed
Chronic Heart Failure and, Complex Sleep Apnea Syndrome
Adaptive Servo-Ventilation in "Real Life" Conditions : the OTRLASV Study
Adaptive Servo-Ventilation (ASV) treatment is routinely prescribed in France. In order to be reimbursed according to the French Social Security rules, the patient treated with an ASV needs to be examined each year.
- Conditions
- Chronic Heart Failure and, Complex Sleep Apnea Syndrome, Obstructive Sleep Apnea Syndrome and, Idiopathic Central Sleep Apnea Syndrome
- Trial name
- OTRLASV (NCT02429986)
- Testing
- Adaptive Servo-Ventilation
- Where
- 5 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Montpellier
Periodic Breathing, Breathing-Related Sleep Disorder
Modified Adaptive Servoventilation (ASV) Compared to Conventional ASV
This study will determine if modified adaptive servoventilation (ASV) is as effective as the conventional ASV in treating periodic breathing.
- Trial name
- NCT01405313
- Testing
- Modified Adaptive Servoventilation Device, Conventional Adaptive Servoventilation device
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- ResMed
Sleep Disordered Breathing, Cheyne Stokes Respiration
Chronic Evaluation of Respicardia Therapy
The purpose of this study is to determine the chronic safety and efficacy of phrenic nerve stimulation on central sleep apnea (CSA).
- Conditions
- Sleep Disordered Breathing, Cheyne Stokes Respiration, Periodic Breathing, Sleep Apnea
- Trial name
- NCT01124370
- Testing
- remedē (TM) system
- Where
- 13 sites in United States, Germany and 2 more
- Volunteers
- 57 people
- Sponsor
- Respicardia, Inc.
Exertional Periodic Breathing
Chemoreflex Gain on Exercise
The purpose of this study is to assess chemoreflex gain on exercise.
- Trial name
- NCT01050179
- Testing
- carbon dioxide
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Periodic Breathing
Developing a New, Dynamic, Therapeutic Pacemaker Algorithm for Stabilising Periodic Breathing in Chronic Heart Failure.
To evaluate whether cardiac output manipulation via a cardiac pacemaker can stabilise ventilation.
- Trial name
- NCT01044407
- Testing
- Pacemaker manipulation
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Imperial College London
Periodic Breathing, Heart Failure
The Cyclocapnic Method for Measurement of Chemosensitivity
We aim to test our method for measuring chemosensitivity (the ventilatory response to a change in carbon dioxide), which uses sinusoidal carbon dioxide stimuli.
- Trial name
- NCT01049256
- Testing
- carbon dioxide
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Imperial College London