Clinical trials: Perineal Laceration
Transperineal Ultrasound, Midwife-led Pushing Training Program
Pushing Using Real-time Sonographic Ultrasound Education
The study aims to assess whether the use of ultrasound during a pushing lesson can facilitate easier and safer childbirth. The research will be conducted at a single hospital and will involve pregnant women in their second…
- Conditions
- Transperineal Ultrasound, Midwife-led Pushing Training Program, Duration of the Second Stage, Coactivation Rates of Pelvic Floor Muscles
- Trial name
- PURSUE (NCT07000240)
- Testing
- Midwife-led ultrasound-guided pushing training group, Midwife-led pushing training only group
- Where
- Italy
- Volunteers
- 136 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstetric Labor Complications
The Effect of Perineal Massage in Childbirth
Objective To examine the effects of perineal massage applied during the action of birth on the frequency of episiotomy procedures, perineal tearing and the duration of the second stage of birth.
- Trial name
- NCT02201615
- Testing
- Perineal massage in childbirth
- Where
- Turkey (Türkiye)
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Parturition, Delivery, Obstetric
Randomized Controlled Trial of the Effectiveness of Perineal Pain and Security of the Suture Led by the Result of Hemostasis Versus Manual Compression Routine Suture Perineal Tears of First Degree During Childbirth
During childbirth, the recommendations have evolved to a restriction of episiotomy. This reduction results in an increase of superficial vaginal and perineal tears.
- Trial name
- ImSOLENCE (NCT02870712)
- Testing
- Suture of perineum, hemostatis by digital compression
- Where
- France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Obstetric Trauma, Infections
Oral Antibiotics After Obstetric Perineal Tear
The purpose of this study is to investigate if 3 dose of oral antibiotics administrated the first day after a vaginal delivery with a second degree obstetric tear will decrease the risk of infection and/or wound dehiscence…
- Conditions
- Obstetric Trauma, Infections, Wound Dehiscence
- Trial name
- REPAIR (NCT05830162)
- Testing
- Bioclavid (Amoxicillin and Clavulanic acid)
- Where
- Denmark
- Volunteers
- 442 people
- Sponsor
- Hanna Jangö
Perineal Tear, Obstetric Trauma
Short Anovaginal Distance is Associated With Obstetric Anal Sphincter Rupture
Anovaginal distance measured by palpation and perineal ultrasound are similar.
- Trial name
- AVD and OASR (NCT03039582)
- Testing
- Bidigital palpation, Perineal ultrasound
- Volunteers
- 151 people
- Sponsor
- Ostergotland County Council, Sweden
Perineal Tear and Episiotomy
The Effect of Mucogyne® Gel on Wound Healing
The aim of this post-market clinical follow up study is to confirm the efficacy and safety of topical application of Mucogyne® gel in the process of wound healing, when used in accordance with its approved labeling, in the…
- Trial name
- ARTHEMIS (NCT05888194)
- Testing
- Mucogyne® gel
- Where
- 3 sites in France
- Volunteers
- 118 people
- Sponsor
- Biocodex
Skin Structures and Soft Tissue Infections, Wound Infection
The PLUS Study: Comparison of VicrylPlus® Versus Vicryl® for Repair of Perineal Tears
INTRODUCTION It is estimated that over 80% of women who give vaginal birth will sustain some form of perineal tear and of these 60-70% will require suturing.
- Trial name
- NCT02863874
- Testing
- VicrylPlus®, Vicryl®
- Where
- Sweden
- Volunteers
- 1,890 people
- Sponsor
- Region Skane
Perineal Trauma, Hands-on Technique
Hands-on vs Hands-off Techniques in Perineal Protection
Perineal tears are frequent during vaginal delivery. This study evaluates the impact of hands-on versus hands-off techniques on perineal and neonatal outcomes to determine the most effective protective strategy.
- Conditions
- Perineal Trauma, Hands-on Technique, Hands-of Technique, Manual Perineal Protection
- Trial name
- MPP (NCT07492940)
- Where
- Italy
- Volunteers
- 737 people
- Sponsor
- Azienda ULSS 8 Berica
Perineal Pain, Birth Satisfaction
The Effect of Birth Ball and Perineal Massage on Perineal Pain, Perineal Trauma and Birth Satisfaction
One of the important causes of perineal trauma is perineal tension. By reducing this tension, perineal trauma can be prevented. Perineal trauma is a birth complication that can be prevented with midwifery approaches.
- Conditions
- Perineal Pain, Birth Satisfaction, Perineal Laceration, Tear, or Rupture During Delivery
- Trial name
- NCT06935643
- Testing
- Birth Ball, Perineal Massage, Control Group
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Perineal Tear, Perineal Laceration (Obstetric)
Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear
To assess the prevalence of pain score for perineum pain following childbirth followed by phase 2 study to assess the analgesic effectiveness of acetaminophen and diclofenac rectal suppository in postpartum perineum pain…
- Trial name
- SuPPerP (NCT03041779)
- Testing
- Diclofenac Sodium 50Mg Suppository, Paracetamol 500Mg Suppository
- Volunteers
- 909 people
- Sponsor
- Clinical Research Centre, Malaysia
Dehiscence Wound, Secondary Perineal Tear
Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour
The goal of this observational study is to make us more aware of the short and long-term outcomes for women having an uncomplicated healing process after a rupture or birth cut in the perineum after giving birth in relation to a…
- Conditions
- Dehiscence Wound, Secondary Perineal Tear, Episiotomy; Dehiscence
- Trial name
- HEAL (NCT06026423)
- Testing
- Clinical examination and pictures, Questionnaire
- Where
- Denmark
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Perineal Tear Resulting From Childbirth
Perineal Massage and Warm Compresses - RCT for Reduce Perineal Trauma During Labor
The aim of this study is to evaluate the effect of a combined perineal massage and warm compresses intervention on the perineum integrity during second stage of labor.
- Trial name
- PeMWaC (NCT05854888)
- Testing
- Perineal Massage and Warm Compresses (PeMWaC), Control Group (Hands-on)
- Where
- Portugal
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Perineal Lacerations
Ritgens Maneuver for the Prevention of Anal Sphincter Tears at Delivery: A Randomized Controlled Trial
The aim of the investigation was to assess whether routine use of the modified Ritgen´s maneuver decreases the risk of anal sphincter injury at delivery, compared with simple manual protection of the perineum.Ritgen´s maneuver…
- Trial name
- NCT00652977
- Testing
- Ritgens maneuver, Standard care (Manual support of the perineum)
- Where
- 2 sites in Sweden
- Volunteers
- 1,623 people
- Sponsor
- Lund University Hospital
Perineum; Rupture, Perineum; Tear
In Vivo Evaluation of Perineal Mechanical Properties During Childbirth
The objective of this work is to evaluate perineal elasticity and deformation and the perineal stresses induced by the fetus during delivery.
- Conditions
- Perineum; Rupture, Perineum; Tear, Perineal Tear
- Trial name
- MecaPer (NCT05556304)
- Testing
- assessment in the 8th month of pregnancy and during delivery
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Vaginal Laceration During Delivery
Antibiotics for Severe Perineal Laceration to Prevent Infection Following Repair
Many women experience severe anal sphincter lacerations during childbirth, which put them at risk for infection, improper healing, and accidental bowel leakage.
- Trial name
- ASPIRe (NCT04573504)
- Testing
- Augmentin/Flagyl or Augmentin/Clindamycin
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Northwestern University
Perineal Lacerations, Delivery, Obstetric
Photobiomodulation for Episiotomies and Perineal Lacerations After Vaginal Delivery.
Episiotomies (EP) and perineal lacerations (PL) following vaginal delivery can lead to complications such as pain, edema, and infection.
- Conditions
- Perineal Lacerations, Delivery, Obstetric, Episiotomy Wound, Photobiomodulation Therapy
- Trial name
- NCT06893315
- Testing
- Photobiomodulation Therapy, Hospital Standard Protocol of treatment for pain and healing
- Where
- Brazil
- Volunteers
- 183 people
- Sponsor
- University of Nove de Julho
Episiotomy, Episiotomy Extended by Laceration
Pelvic Floor Training Combined With Perineal Massage Reduces Episiotomy to 5.7%
Episiotomy, a surgical incision of the perineum performed during the second stage of labor, was once widely advocated for the prevention of severe perineal lacerations.
- Conditions
- Episiotomy, Episiotomy Extended by Laceration, Pelvic Floor Awareness
- Trial name
- NCT07626333
- Testing
- Standart antenatal care, Pelvic Floor Muscle Exercises (PMFE), Swiss Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- Batman Training and Research Hospital
Perineal Tear, Episiotomy Extended by Laceration
Pushing and Manual Perineal Protection Techniques
Perineal trauma during vaginal delivery is very common, especially in countries with a high prevalence of episiotomy. Perineal traumas can range from tears limited to the skin, subcutaneous and vaginal mucosa to severe tears…
- Conditions
- Perineal Tear, Episiotomy Extended by Laceration, Labor Complication
- Trial name
- NCT04823598
- Testing
- Coached pushing and Finnish manual perineal protection, Uncoached pushing and Hands-poised perineal protection
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Istinye University
Perineal Tear
A Device Designed to Protect the Perineum During Labor
Objective: To investigate the protective effects of a newly invented device for reducing tears in the perineum during vaginal childbirth.
- Trial name
- NCT01533467
- Testing
- Perineal protection device
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Helsingborgs Hospital
Pregnancy Complications
Obstetric Perineal Trauma and Physiotherapy
The main objective is to investigate effects of perineal trauma at birth on women´s health and whether early physiotherapy improves pelvic floor strength.
- Trial name
- NCT02682212
- Testing
- Physiotherapy intervention
- Where
- Iceland
- Volunteers
- 84 people
- Sponsor
- Landspitali University Hospital