Clinical trials: Periimplant Diseases
Teeth Absent, Tooth-loss
Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment.
A dental implant is an alloplastic material surgically inserted in a residual bone ridge, mainly with a prosthetic foundation. Nowadays the most widely used implants and with a higher degree of scientific evidence are the…
- Conditions
- Teeth Absent, Tooth-loss, Tooth Extraction, Dental Implant
- Trial name
- NCT05118815
- Testing
- Slim abutment, Standard abutment
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Mucositis
Use of Probiotics in Oral Health of Patients With Dental Implants
The aim of this study was evaluate the effects of the oral probiotic Lactobacillus reuteri Prodentis upon the peri-implant health of edentulous patients with dental implants and peri-implant mucositis, establishing comparisons…
- Trial name
- NCT01974596
- Testing
- Probiotic tablets of Lactobacillus reuteri
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Horizontal Alveolar Bone Defect, Alveolar Bone Loss
Evaluation of Mineralized Plasmatic Matrix With and Without Collagen Membrane in Peri-implant Bone Regeneration
This study focuses on comparing the effect of MPM with or without collagen membrane on delayed implant placement in anterior maxillary aesthetic zone.
- Trial name
- NCT04816110
- Testing
- mineralized plasmatic matrix with collagen membrane, mineralized plasmatic matrix (MPM) without collagen membrane
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Periimplantitis
Application of Local Melatonin in Peri-implantitis
A randomized clinical trial was carried out in patients affected by peri-implantitis with a follow-up of 60 days. Melatonin 1.9 mg or placebo was applied locally to the peri-implant defect after nonsurgical debridement.
- Trial name
- MEL19 (NCT06816277)
- Testing
- Desbridamiento de periimplantitis, Aplicación de melatonina
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Periimplantitis, Periimplant Diseases
Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry
Aim: The aim of this prospective, randomized, parallel arm, blind clinical trial is to compare the clinical and radiographic outcomes following non-surgical treatment of mild peri-implant defects using Labrida Bioclean with or…
- Trial name
- NCT06695559
- Testing
- Labrida Bioclean, Tetracycline slurry
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Peri-Implantitis and Peri-implant Mucositis, Peri-implant Mucositis
Salivary Minerals in Patients With Peri-implantitis
Patients included in the study will be recruited after arriving at the Faculty of Dentistry of the University of Zagreb. During the clinical examination, the patient's periodontal status (bleeding during probing, and the depth of…
- Conditions
- Peri-Implantitis and Peri-implant Mucositis, Peri-implant Mucositis, Periimplant Bone Loss, Periimplant Diseases
- Trial name
- mineral-perio (NCT05897736)
- Volunteers
- 25 people
- Sponsor
- University of Zagreb
Toothbrushing, Periimplant Diseases
Manual Versus Sonic-powered Toothbrushing for Plaque Reduction in Patients with Peri-implant Mucositis
Aim: To compare the effect of manual and sonic-powered toothbrushing on biofilm control in patients with peri-implant mucositis.
- Trial name
- NCT06800625
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Hacettepe University
Mucositis Oral
Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Peri-implant disease is an inflammatory process of bacterial etiology that can affect the tissues around the implants and can be classified as peri-implant mucositis or peri-implantitis.
- Trial name
- Mucosite prob (NCT04187222)
- Testing
- Mechanical debridements, Bifidobacterium animalis subsp. lactis
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periimplant Diseases, S100A8
Diode Laser and S100A8 in Peri-Implantitis
Purpose: The aim of this study was to compare the effectiveness of diode laser and combined treatment protocols, applied in addition to mechanical debridement, in the treatment of peri-implantitis on clinical periodontal…
- Conditions
- Periimplant Diseases, S100A8, Biomarkers, Calprotectin
- Trial name
- NCT07524153
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Periimplant Bone Loss, Marginal Periimplant Bone Level
Changes on the Interproximal Bone Level on Direct Prostheses or With Intermediate Abutments
Study Title: Changes on the Interproximal marginal bone level after CAD-CAM designed bridges directly placed on bone-level implants, or with intermediate abutments. A Randomized Clinical Trial.
- Conditions
- Periimplant Bone Loss, Marginal Periimplant Bone Level, Periimplantitis
- Trial name
- NCT04369170
- Testing
- prosthesis connected directly to the implants, Intermediate abutment
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Santiago de Compostela
Dental Diseases
Investigation of Bacterial Adhesion and Bactericide Effect ex Vivo on Different Implant Restoration Materials
Investigation of bacterial adhesion and bactericide effect ex vivo on different implant restoration materials
- Trial name
- NCT04657757
- Testing
- Intraoral apparatus
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Periimplant Diseases, Dental Implant Failure
Microbiological Evaluation of the Effectiveness of Different Surface Decontamination Protocols for Dental Implants
The purpose of this prospective clinical study is to evaluate and compare the effectiveness of different cleaning (decontamination) methods for dental implants affected by peri-implantitis.
- Conditions
- Periimplant Diseases, Dental Implant Failure, Dental Implant Complications
- Trial name
- NCT07529444
- Testing
- Laser Photodynamic Therapy (PDT), GalvoSurge Electrolytic Cleaning, 0.2% Chlorhexidine Gluconate
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- University of Zagreb
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Neurogenic Inflammation, Periimplant Diseases
Neurogenic Inflammation in Peri-implant and Periodontal Diseases
Regulatory effects of some neuropeptides substance-P (SP), neurokinin-A (NKA), calcitonin gene-linked peptide (CGRP) and neuropeptide-Y (NPY) )on inflammatory responses in periodontal disease has been described; however, the…
- Conditions
- Neurogenic Inflammation, Periimplant Diseases, Periodontal Diseases, Gingival Crevicular Fluid
- Trial name
- NCT03663140
- Testing
- gingival crevicular fluid (GCF) and peri-implant sulcular fluid(PISF) collection
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Alveolar Bone Loss, Dental Implant
Evaluation of the Effect of Periimplant Soft Tissue Phenotype on Marginal Bone Loss
The goal of this clinical trial to test the effect of periimplant soft tissue phenotype in the participants with implant placed and at least 1 year after implant loading. The main questions it aims to answer are: 1.
- Conditions
- Alveolar Bone Loss, Dental Implant, Periimplantitis
- Trial name
- NCT05640284
- Testing
- Nuclear Factor-Kappa B Ligand (RANKL) analysis, Osteoprotegerin (OPG) analysis, Tumor Necrosis Factor Alpha (TNF-α) analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Necmettin Erbakan University
Periimplant Crestal Bone Level Changes
Influence of Platform-switching on Bone Level Alterations: a 3 Year Randomized Clinical Trial (RCT).
The concept of platform-switching has been introduced to implant dentistry based on clinical observations of reduced periimplant crestal bone loss.
- Trial name
- NCT01917305
- Testing
- platform-shifted implant
- Volunteers
- 25 people
- Sponsor
- Søren Jepsen
Peri Implantitis, Peri Implant Mucositis
Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid
Despite technological advances that have significantly improved dental implant osseointegration and survival rates, biological complications such as peri-implantitis and peri-implant mucositis are common around the implant.
- Trial name
- NCT07280754
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University