Clinical trials: Perianal Abscess
Crohns Disease, Fistula
Study to Look at Benefit of Surgical Drainage Before Beginning Medical Therapy for Crohns Perianal Fistulas
This study is looking at the advantage of establishing surgical drainage for Crohn's fistulas and abscesses prior to starting medical therapy.
- Conditions
- Crohns Disease, Fistula, Abscess
- Trial name
- NCT01145365
- Testing
- Exam under anesthesia (EUA)
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center
Perianal Abscess, Perianal Infections
Packing of Perianal Abscess Cavities
The aim of this trial is to compare internal wound packing to no packing in postoperative management following incision and drainage of perianal abscess.
- Conditions
- Perianal Abscess, Perianal Infections, Peri Rectal Abscess, Abscess; Anus
- Trial name
- PPAC2 (NCT03315169)
- Testing
- External dressing, Packing of perianal abscess cavity
- Where
- 50 sites in United Kingdom
- Volunteers
- 433 people
- Sponsor
- Manchester University NHS Foundation Trust
Fournier Gangrene, Perianal Abscess
The Immunological Differences Between Fournier Gangrene and Perianal Abscess
Although it is rarely observed, necrotizing fasciitis progresses with high mortality and serious complications. Fournier's gangrene is a specific form of necrotizing fasciitis.
- Trial name
- NCT05529628
- Testing
- Cytokine levels
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Perianal Abscess
Packing of Perianal Abscess Cavities Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity
The aim of this study is to compare the effect of packing and non-packing on the healing rate of perianal abscess cavities. Secondary objectives are to assess quality of life, cost effectiveness and rate of abscess recurrence and…
- Trial name
- PPAC (NCT01739478)
- Testing
- Packing of abscess cavity, External dressing
- Volunteers
- 300 people
- Sponsor
- North Western Research Collaborative
Perianal Abscess, Anal Fistulas
Multicenter Study for Diagnosis and Treatment of Perianal Abscesses
Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife.
- Conditions
- Perianal Abscess, Anal Fistulas, Incontinence
- Trial name
- NCT02306382
- Testing
- Perianal abscess drainage, 3D ultrasonography
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Umeå
Perianal Abscess, Perianal Fistula
Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial
Most perianal abscesses (PA) result from an infection originating in anal crypts that extend into anal glands in the intersphincteric plane.
- Trial name
- PARFAIT (NCT04549311)
- Testing
- Antibiotic 1 arm (amoxicillin + clavulanic acid), Antibiotic 2 arm (ciprofloxacin + metronidazole)
- Where
- 3 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Perianal Abscess
Study on Dynamic Multimodal Analgesia Regimen Integrated With Traditional Chinese and Western Medicine After Perianal Abscess Surgery
Background:Perianal abscess is a common acute anorectal pyogenic disease (8%-25% of anorectal illnesses), mainly seen in men aged 20-40.
- Trial name
- NCT07744594
- Testing
- TCM sitz bath
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The Affiliated Hospital of Putian University
Anal Fistulas
Aspiration Treatment of Perianal Abscess
The purpose of this study is to compare aspiration and oral antibiotics with surgical incision in the treatment of perianal abscesses in terms of recurrence and subsequent fistula formation.
- Trial name
- NCT02585141
- Testing
- MEDIPLAST® (aspiration), incision, Clindamycin
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- University of Southern Denmark
Inflammatory Bowel Disease, Perianal Fistula
Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease
To show that prevalence of inflammation of the small bowel in patients with anorectal disease is under-diagnosed based on colonoscopy ileoscopy alone.
- Conditions
- Inflammatory Bowel Disease, Perianal Fistula, Perianal Abscess
- Trial name
- NCT00972088
- Testing
- capsule endoscopy
- Where
- 3 sites in Israel
- Volunteers
- 26 people
- Sponsor
- Bikkur Holim Hospital
Perianal Fistula, Perianal Fistula Due to Crohn's Disease
Semiflex Assisted Vacuum Therapy for Perianal Abscesses/Sinuses and Fistula: a Pilot Study
Rationale: Perianal fistulas are a common, invalidating problem for which a more effective and widely applicable treatment is necessary.
- Conditions
- Perianal Fistula, Perianal Fistula Due to Crohn's Disease, Perianal Abscess
- Trial name
- Semiflex Pilot (NCT06446635)
- Testing
- Semiflex Dome Catheter System
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Perianal Abscess
Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces
This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery.
- Trial name
- NCT07155356
- Testing
- Red light exposure, Red-blue light exposure
- Where
- China
- Volunteers
- 222 people
- Sponsor
- The Affiliated Hospital of Putian University
Clinical Application of Dynamic Multimodal Analgesia Regimen After Perianal Abscess Surgery
Clinical Application of Dynamic Multimodal Analgesia Regimen After Perianal Abscess Surgery
This study aims to investigate whether the full-course multimodal analgesia regimen based on dynamic assessment (including the integrated traditional Chinese and Western medicine mode) can alleviate postoperative pain, reduce…
- Trial name
- NCT07358065
- Testing
- the traditional analgesic mode, Western Medicine Multimodal Analgesia, Integrated Traditional Chinese and Western Medicine Multimodal Analgesia
- Where
- China
- Volunteers
- 135 people
- Sponsor
- The Affiliated Hospital of Putian University
Anal Abscess, Perianal Abscess
Abces After Incision: Recurrence or Not?
The French School of Proctology assumes that any anal or perianal abscess is related to an anal fistula and therefore requires treatment at the risk of recurrence of the abscess.
- Trial name
- ABCINCIS (NCT05193032)
- Where
- France
- Volunteers
- 109 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Joint Dislocation, Perianal Abscess
Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults
The purpose of this study is to describe the safety and efficacy of nitrous oxide administration for pain and anxiety before propofol in patients requiring any procedure under sedation in the Emergency Department.
- Conditions
- Joint Dislocation, Perianal Abscess, Abscess
- Trial name
- NCT02410707
- Testing
- Nitrous Oxide arm, Propofol, Oxygen
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Albert Einstein Healthcare Network
Wrist-Ankle Acupuncture
Application Effects of Wrist-Ankle Acupuncture in Patients With Different Types of Pain Following Perianal Surgery
This study is a prospective clinical observation designed to evaluate the analgesic effect of wrist-ankle acupuncture in patients with different types of pain after perianal surgery, as well as its applicability.
- Trial name
- NCT07340307
- Testing
- wrist-ankle acupuncture
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The Affiliated Hospital of Putian University
Perianal Abscess
Perianal Abscess Packing Randomized ControlledTrial Pilot Study
TITLE Perianal Abscess Packing (PAP): a randomised controlled trial (Pilot study) DESIGN Randomised controlled trial. HYPOTHESIS In patients with perianal abscesses incision and drainage without packing the subsequent cavity will…
- Trial name
- NCT01853267
- Testing
- Intervention Group (Non-Packing), Control group (Packing)
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Imperial College London
Perianal Crohn Disease, Perianal Fistula
The Impact of Perianal Disease on Patient's Sex Life
Perianal diseases, such as perianal abcesses, anal fistulae and perianal Crohn's disease, are often associated with significant physical symptoms, including pain and chronic drainage.
- Conditions
- Perianal Crohn Disease, Perianal Fistula, Fistula in Ano, Perianal Abscess
- Trial name
- SEXTON (NCT07519850)
- Testing
- Patient Reported Outcome Assessment (Questionnaires)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- AHEPA University Hospital
Anal Fistula
Do Antibiotics Prevent Anal Fistulae Formation?
Purpose: This randomized study assesses the effects of antibiotics on the formation of fistulae after drainage of anorectal abscesses.
- Trial name
- NCT01012843
- Testing
- Amoxicillin-Clavulanate
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Ankara University
Perianal Abscess, Anal Fistula
Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess
The goal of this clinical trial is to learn if antibiotics can prevent the formation of fistula-in-ano after incision and drainage of a first time of perianal abscess in adults.
- Trial name
- RAPID (NCT07704359)
- Testing
- Amoxicillin + Clavulanate, Ciprofloxacin + Metronidazole
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Illinois at Chicago
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital