Clinical trials: Periampullary Carcinoma
Periampullary Carcinoma, Pancreatic Fistula
Trial of Omental Roll-up Technique on Pancreato-jejunostomy Anastomosis for Reducing Perioperative Complication in Patients Undergoing Pancreatoduodenectomy
Despite the fact that pancreatoduodenectomy is the standard treatment of malignant tumor at periampullary area, the morbidity and mortality rate with intra-abdominal collection, post pancreatectomy hemorrhage, and delayed gastric…
- Trial name
- NCT03083938
- Testing
- Omental Roll-up
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Pancreatic Carcinoma
Preoperative Biliary Drainage in Resectable Pancreatic or Periampullary Cancer
The purpose of this study is to demonstrate that preoperative biliary drainage using self-expanding metal stents (SEMS) does not negatively impact overall surgical outcomes in patients undergoing pancreaticoduodenectomy for…
- Trial name
- NCT01774019
- Testing
- WallFlex™ Biliary RX Fully Covered/Uncovered Stent System
- Where
- 11 sites in United States, Australia and 7 more
- Volunteers
- 284 people
- Sponsor
- Boston Scientific Corporation
Periampullary Carcinoma
Total Laparoscopic vs Open Pancreaticoduodenectomy for the Treatment of Periampullary Adenocarcinomas
Laparoscopic pancreaticoduodenectomy (LPD), a surgical option for nonpancreatic periampullary adenocarcinoma (NPPA), is a complex procedure that has become increasing popular.
- Trial name
- NCT07388082
- Testing
- Conventional open pancreaticoduedectomy, Total laparoscopic pancreaticoduedectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Acinar Cell Carcinoma, Ampulla of Vater Adenocarcinoma
WASH Trial: Intraoperative Lavage as a Treatment for Pancreatic Cancer
The goal of this clinical trial is to learn if a special washing treatment used during surgery can help people with pancreatic cancer live longer.
- Conditions
- Acinar Cell Carcinoma, Ampulla of Vater Adenocarcinoma, Cholangiocarcinoma, Duodenal Adenocarcinoma
- Trial name
- NCT02757859
- Testing
- Pancreatectomy, Lavage
- Where
- United States
- Volunteers
- 845 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Hepatocellular Carcinoma, Cholangiocellular Carcinoma
Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers
This is a single arm phase II trial of Gemcitabine and Oxaliplatin (Gem-Ox) with Erlotinib (Tarceva) for the treatment of hepatocellular carcinoma (HCC) and biliary tree cancer (BTC) patients with platelet counts 100,000/µL.
- Conditions
- Hepatocellular Carcinoma, Cholangiocellular Carcinoma, Cholangiocarcinoma of the Extrahepatic Bile Duct, Bile Duct Cancer
- Trial name
- Gem-ox (NCT00832637)
- Testing
- Cisplatin, Erlotinib, Gemcitabine
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- New Mexico Cancer Research Alliance
Pancreatic Tumor, Periampullary Carcinoma Resectable
Role of CTC´s Spread During Pancreaticoduodenectomy in Patients With Pancreatic and Periampullary Tumors
This multicentre, prospective and randomized study aims(1:1) to compare the rate of recurrence, metastasis and survival according to the levels of intraoperative circulating tumor cells (CTCs) during cephalic…
- Conditions
- Pancreatic Tumor, Periampullary Carcinoma Resectable, Circulating Tumor Cells, Metastasis
- Trial name
- CETUPANC (NCT03340844)
- Testing
- No Touch (NT), Superior Mesenteric Artery First (SMA)
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Pancreatic Cancer, Cancer of the Duodenum
Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy
Pancreatoduodenectomy carries high morbidity rates even in high-volume centers. Postoperative complications often preclude or delay adequate oral nutrition and nutritional support may be required.
- Conditions
- Pancreatic Cancer, Cancer of the Duodenum, Cholangiocarcinoma, Chronic Pancreatitis
- Trial name
- NCT01642875
- Testing
- Enteral nutrition, Oral nutrition
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Medical University of Warsaw
Pancreatic Cancer, Periampullary Cancer
Preoperative Detection of Lymph Node Metastases in Pancreatic and Periampullary Carcinoma Using USPIO MRI
Adenocarcinoma's of the pancreas and periampullary region (distal bile duct, ampulla of Vater and duodenum) are cancers with a poor survival.
- Trial name
- NANO-PANC (NCT04311047)
- Testing
- USPIO-enhanced MRI
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Radboud University Medical Center
Pancreatic Cancer, Common Bile Duct Diseases
A Prospective Clinical Study Using an Artery-first Intermediate Approach in Robot-assisted Pancreaticoduodenectomy
Pancreaticoduodenectomy, as a standard surgical procedure for malignant tumors of the head of the pancreas, ampulla and distal common bile duct, has brought the hope of clinical cure for these diseases.In the whole surgical…
- Conditions
- Pancreatic Cancer, Common Bile Duct Diseases, Periampullary Carcinoma
- Trial name
- NCT05660915
- Testing
- Intermediate approach, Standard approach
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of University of South China
Pancreatic Cancer, Pancreatic Neoplasms
Wearable-Supported Prehabilitation and Rehabilitation for Patients Undergoing Surgery for Pancreatic Cancer
The goal of this clinical trial is to evaluate whether a wearable-enabled prehabilitation and rehabilitation pathway can improve recovery and post-operative outcomes in adults undergoing surgery for pancreatic cancer or related…
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Periampullary Carcinoma, Pancreatic Surgery
- Trial name
- POWR-PaC (NCT07772258)
- Testing
- Corsano CardioWatch, Prehab4Cancer Programme
- Volunteers
- 120 people
- Sponsor
- Manchester University NHS Foundation Trust
Periampullary Carcinoma, Pancreatic Cancer
Reoperation After Pancreaticoduodenectomy
The aim of this study is to outline the incidence of early and late reoperation after PD, examine the risk factors for early surgical intervention and its impact on the surgical outcome, hospital stay, diseases recurrence and…
- Trial name
- NCT04387903
- Testing
- Surgical re-interventionafter pancreaticoduodenectomy
- Volunteers
- 1,000 people
- Sponsor
- Mansoura University
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University
Pancreatic Cancer, Periampullary Carcinoma
Evaluation of A New Digestive Reconstruction Procedure Following Pancreatoduodenectomy
The purpose of this study is to evaluate the validity and safety of a modified operative procedure of digestive tract reconstruction following pancreatoduodenectomy which enables the pancreatic juice and bile to bypass at the…
- Trial name
- NCT01931449
- Testing
- Modified method of digestive tract reconstruction, Routine digestive tract reconstruction
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
Stomach Neoplasms, Pancreatic Neoplasms
Laparotomy, Laparoscopy, da Vinci System
1. This study looks at whether newer surgical tools-like the da Vinci robotic system-can help patients recover better after major abdominal surgeries.
- Conditions
- Stomach Neoplasms, Pancreatic Neoplasms, Liver Neoplasms, Periampullary Neoplasms
- Trial name
- NCT07034495
- Where
- Taiwan
- Volunteers
- 486 people
- Sponsor
- National Chung Hsing University
Acupuncture, Gastrointestinal Function
Perioperative Electroacupuncture After Operation
Evaluate the effect of perioperative electroacupuncture on rapid rehabilitation for the pancreatic cancer and periampullary carcinoma patients after operation .
- Trial name
- NCT03291561
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Periampullary Carcinoma Resectable
Pancreatoduodenectomy With Mesopancreas Dissection.A Prospective Study Comparing Artery-first Approach Versus Standard Approach
The definitions for R0 and R1 margin status after resection for pancreatic cancer are controversial.Various studies showed the rate of noncurative resections of 15- 35 % but with modified pathological examination (R1/R2) revealed…
- Trial name
- NCT03224832
- Testing
- Artery-first Approach, Standard Approach
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Periampullary Carcinoma Resectable
The Effect of Braun Anastomosis on Delayed Gastric Emptying (DGE) in Reconstruction After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is the only curative procedure for periampullary malignant tumors. Although modern perioperative management has greatly reduced postoperative mortality, delayed gastric emptying (DGE) remains one of…
- Trial name
- NCT07681128
- Testing
- Braun anastomosis on delayed gastric emptying (DGE) in reconstruction after pancreaticoduodenectomy, Patients undergo PD with standard antecolic Billroth II reconstruction without Braun enteroenterostomy.
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Periampullary Carcinoma Nos
Effect of Probiotics in Patients Undergoing Surgery for Periampullary Neoplasms
The purpose of this study is to evaluate the effect of the probiotic use in patients with periampullary cancers undergone curative or palliative treatment considering nutritional status, postoperative complications, infection…
- Trial name
- NCT01468779
- Testing
- Probiotics, Sugar pill
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Ampullary Carcinoma, Duodenal Adenocarcinoma
Modified Single-Incision Plus One-Port Versus Conventional Five-Port Laparoscopic Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas
This multicenter, randomized, controlled, non-inferiority trial will compare modified single-incision plus one-port laparoscopic pancreaticoduodenectomy (mSILPD+1) with conventional five-port laparoscopic pancreaticoduodenectomy…
- Conditions
- Ampullary Carcinoma, Duodenal Adenocarcinoma, Distal Cholangiocarcinoma
- Trial name
- NCT07744087
- Testing
- Modified Single Incision plus one-port Laparoscopic Pancreaticoduodenectomy, Conventional Laparoscopic Pancreaticoduodenectomy
- Where
- 4 sites in China
- Volunteers
- 232 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Periampullary Carcinoma Nos
Pancreas-sparing Duodenectomy Versus Pancreatoduodenectomy for Early-stage Periampullary Carcinoma
The purpose of this study is to investigate the feasibility, safety, and long-term prognosis of pancreas-sparing duodenectomy with regional lymphadenectomy in the treatment of early-stage (pTis/pT1/pT2) periampullary carcinoma…
- Trial name
- NCT01291927
- Testing
- Pancreas-sparing duodenectomy, Pancreaticoduodenectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Southwest Hospital, China