Clinical trials: Peri-Implantitis, open to volunteers
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-implantitis
Reconstructive Treatment of Peri-implantitis With Combined Defects
The aim of this randomized clinical study is to assess the additional clinical benefit of incorporating a resorbable collagen membrane (CM) alongside a xenogeneic bone graft-specifically, deproteinized bovine bone mineral with…
- Trial name
- NCT06957652
- Testing
- DBMM-C plus Resorbable collagen membrane, DBMM-C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Peri-implantitis
Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis
Peri-implantitis is a chronic inflammatory disease characterized by plaque-associated inflammation of the peri-implant mucosa and progressive loss of supporting bone around dental implants, which may ultimately lead to implant…
- Trial name
- NCT07569432
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Biruni University
Peri-implantitis, Periodontitis
Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis
This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients…
- Conditions
- Peri-implantitis, Periodontitis, Non-surgical Periodontal Therapy
- Trial name
- MINST vs NSPT (NCT07466966)
- Testing
- Non-Surgical Peri-implant Therapy (NSPT), Minimally-Invasive Non-Surgical Therapy (MINST)
- Where
- Czechia
- Volunteers
- 106 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Peri-implantitis
Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial
The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by…
- Trial name
- NCT07391202
- Testing
- Non-Surgical Peri-Implant Therapy without Crown, Non-Surgical Peri-Implant Therapy with Crown
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Peri Implantitis
Comparison of Two Non-surgical Procedure to Manage Gum Disease Around Implants.
Research Question: Can a minimally invasive, non-surgical treatment approach (MINST) be more effective than the current standard non-surgical method in treating peri-implantitis, a common inflammatory condition affecting dental…
- Trial name
- NCT07365722
- Testing
- Non-Surgical Periodontal treatment (NSPT), Minimally-invasive non-surgical therapy of peri-implantitis
- Volunteers
- 80 people
- Sponsor
- King's College London
Peri-Implantitis
Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis.
The goal of this clinical trial is to compare non-surgical treatment by mechanical debridement with air-polishing in peri-implantitis.
- Trial name
- NCT05683405
- Testing
- Non-surgical treatment of peri-implantitis with mechanical debridement, Non-surgical treatment of peri-implantitis with air polishing
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Tannhelsetjenestens Kompetansesenter for Nord-Norge
Peri-implantitis
Effect of Metallic Particles on the Progression of Peri-Implantitis
This observational cross-sectional study aims to investigate the presence and characteristics of metallic micro- and nanoparticles in peri-implant tissues and their potential association with peri-implantitis progression, the…
- Trial name
- NCT07792499
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Peri-Implantitis
Regenerative Treatment of Peri-implantitis
The purpose of this study is to study the use of a new type of d-PTFE membrane called reinforced PTFE Mesh (RPM) with dental surgery.
- Trial name
- NCT06153212
- Testing
- Membrane placement with bone grafting
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Peri-implantitis
Electrolytic Surface Decontamination in the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial
The goal of this clinical trial is to learn whether adjunctive electrolytic surface decontamination can improve the outcomes of surgical treatment of peri-implantitis.
- Trial name
- NCT07644975
- Testing
- Electrolytic Surface Decontamination, Conventional Surgical Treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Periodontal Disease, Microbiology
Longitudinal Evaluation of Several Modalities of Treatment of Peri-implantitis: 5 to 23 Years Follow-up
To evaluate the peri-implant conditions of patients undergoing different surgical and non-surgical techniques, associated or not with regenerative therapies after long periods of time (between 5 and 23 years) 3.
- Trial name
- longitudinal (NCT07684001)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Peri-Implantitis and Peri-implant Mucositis
SPiT-frequency I_Peri-implant Mucositis
This is an interventional clinical study on the peri-implant treatment necessary to improve the clinical conditions surrounding dental implants registered with peri-implant inflammation.
- Trial name
- NCT06737328
- Testing
- Submocosal instrumentation using a ultrasonic device (PEEK). Submucosal cleaning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Oslo
Peri Implant Mucositis, Peri Implantitis
Study on the Treatment of Dental Implants Using the AmbiJet System for Peri-implantitis and Peri-implant Mucositis
Inflammation of the tissue surrounding a dental implant (peri-implantitis or peri-implant mucositis) can lead to implant loss in advanced stages.
- Trial name
- AmbiJet-FIH (NCT07722715)
- Testing
- AmbiJet cold plasma system, Standard Mechanical Debridement (S3 Guideline)
- Where
- Ukraine
- Volunteers
- 26 people
- Sponsor
- Freiburger Medizintechnik GmbH
Peri-Implantitis, Bone Resorption
Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF)
Platelet-rich fibrin (PRF) is a second-generation platelet concentrate used for tissue and bone regeneration. PRF releases growth factors such as TGF-β, PDGF, VEGF, IGF, and FGF, which are known to promote wound healing and bone…
- Conditions
- Peri-Implantitis, Bone Resorption, Platelet-Rich Fibrin
- Trial name
- PRF (NCT06679283)
- Testing
- Open flap debridement with a chemo-electric device + PRF, Open flap debridement with a chemo-electric device alone (control)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Peri-Implantitis, Peri-Implant Health
Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis
The purpose of the present study is to compare the 1-year clinical, radiographic and microbiological outcomes and patients' satisfaction following surgical treatment of peri-implantitis after applying two different surface…
- Trial name
- NCT05899933
- Testing
- Non-surgical peri-implant therapy, Implantoplasty, Erythritol Air-abrasive device
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Periodontal Disease, Periodontal Surgery
Serum Inflammatory Protein Concentration During Dental Treatment
The goal of this observational study is to study the molecular markers of stress in blood samples from people who are having periodontal surgery.
- Trial name
- NCT07468929
- Testing
- Blood samples for inflammatory markers, periodontal surgery, Periodontal maintenance
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Dental Implant Failed, Peri-Implantitis
Comparison of Dental Implants with Different Surface Properties
This controlled, parallel clinical study aims to compare the effect of fixed prosthetic restorations placed in the posterior region with different implant surfaces on clinical and peri-implant marginal bone loss.
- Trial name
- NCT06508723
- Testing
- Dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Periimplantitis
Evaluation of the Effects of the Low-level Laser Therapy as an Adjunct to Nonsurgical Treatment in Patients With Periimplantitis
The main objective of this study is to evaluate the clinical efficacy of low-level laser therapy (LLLT) in addition to non-surgical periodontal treatment in patients with peri-implantitis.
- Trial name
- NCT07128134
- Testing
- Low Level Laser Therapy, Non-surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Mustafa Kemal University
Peri-implantitis, Periodontitis
Transcriptome, Proteome and Microbiome Profile in Periodontal and Peri-implant Diseases
1. To investigate the transcriptomic profile of periodontitis and peri-implantitis. Patients with defined periodontitis, at two non-adjacent teeth and peri-implantitis at ≥ one implant in function of ≥ one year, will be included…
- Trial name
- NCT06262035
- Testing
- Periodontitis and Peri-implantitis
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet