Clinical trials: Peri-Implantitis
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-implantitis
Reconstructive Treatment of Peri-implantitis With Combined Defects
The aim of this randomized clinical study is to assess the additional clinical benefit of incorporating a resorbable collagen membrane (CM) alongside a xenogeneic bone graft-specifically, deproteinized bovine bone mineral with…
- Trial name
- NCT06957652
- Testing
- DBMM-C plus Resorbable collagen membrane, DBMM-C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Peri-implant Mucositis, Peri-Implantitis
Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease.
The aim of this study is to analyse contiguous dental implants and its peri-implant status depending on different inter-implant distances.
- Trial name
- NCT06364982
- Testing
- Two contiguous dental implants placed with less ≤ 3mm from each other., Two contiguous dental implants placed with > 3mm from each other.
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-Implantitis
Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study
The American Association of Oral and Maxillofacial Surgeons estimated that 69% of adults ages 35 to 44 have lost at least one permanent tooth.
- Trial name
- NCT03100435
- Testing
- Er:YAG Laser, Carbon Fiber Curette
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Tufts University
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Bone Resorption, Diabetes
Application of Information-Motivation-Behavioral Model-based Continuity of Care on the Peri-implantitis Recovery in Diabetic Implant Overdenture Patients
The investigators recruited 32 diabetic IOD patients with a total of 110 problematic implants who had completed the treatment for peri-implantitis between January 2021 and March 2023 as research subjects.
- Trial name
- NCT06103799
- Testing
- IMB model-based continuity of care
- Where
- China
- Volunteers
- 32 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Peri-implantitis
Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis
Peri-implantitis is a chronic inflammatory disease characterized by plaque-associated inflammation of the peri-implant mucosa and progressive loss of supporting bone around dental implants, which may ultimately lead to implant…
- Trial name
- NCT07569432
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Biruni University
Peri-Implantitis, Peri-implant Mucositis
Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration
Various types of periodontal probes (e.g., metal probes, plastic/bendable probes, electronic periodontal probes) are used for peri-implant pocket depth registration; however, depending on the shape and size of the prosthetic…
- Trial name
- NCT05332327
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Malmö University
Peri-Implantitis
Resective Surgical Treatment of Peri-implantitis.
Surgical treatment of peri-implantitis can be regenerative or resective, depending on defect configuration. The aim of resective therapy of peri-implantitis is to reduce the severity of soft tissue inflammation and stabilize…
- Trial name
- NCT04337645
- Testing
- surgical treatment of peri-implantitis
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Peri-Implantitis
Guided Bone Regeneration of Peri-implant Defects Comparing Submerged Versus Non-submerged Healing
Objective: the objective of the present randomized clinical trial is to compare changes in radiographic peri-implant bone defect fill after regeneration of peri-implant intrabony defects with a submerged versus a non-submerged…
- Trial name
- NCT03900741
- Testing
- Submerged healing, Non-submerged healing
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ana Molina Villar
Peri-implantitis
Expression of Epithelial-Mesenchymal Transition Associated Markers in Peri-implant Tissues
Peri-implantitis is an inflammation of bacterial etiology characterized by inflammation of mucous membranes and bone loss around the dental implant.
- Trial name
- NCT05832541
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Peri-implant Mucositis, Peri-Implantitis
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
Due to the limited efficacy of its treatment modalities, there is a stringent need to improve the prevention and early diagnosis of peri-implantitis.
- Trial name
- NCT04283903
- Testing
- PICF
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Complutense de Madrid
Peri-implantitis, Periodontitis
Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis
This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients…
- Conditions
- Peri-implantitis, Periodontitis, Non-surgical Periodontal Therapy
- Trial name
- MINST vs NSPT (NCT07466966)
- Testing
- Non-Surgical Peri-implant Therapy (NSPT), Minimally-Invasive Non-Surgical Therapy (MINST)
- Where
- Czechia
- Volunteers
- 106 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Dental Implant Failed
Clinical and Radiographic Evaluation of Dental Implants Installed Between 2004 and 2010
The convenience sample to be included in the present study will consist of all individuals who had implants installed at the Dentistry Clinic of the University Santo Amaro, between the years 2004 and 2010.
- Trial name
- implants (NCT04236622)
- Testing
- Periodontal clinical exam
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- Universidade Metropolitana de Santos
Peri-implantitis
Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial
The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by…
- Trial name
- NCT07391202
- Testing
- Non-Surgical Peri-Implant Therapy without Crown, Non-Surgical Peri-Implant Therapy with Crown
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Peri-Implantitis
Combined Er:YAG And Nd:YAG Laser Protocol For Treatment Of Peri-Implantitis
A laser treatment for periimplantitis using two different wavelengths (Er:YAG and Nd:YAG) will be compared to standard treatment in a randomized clinical trial.
- Trial name
- NCT03819075
- Testing
- Lightwalker Laser (Fotona), standard
- Where
- Portugal
- Volunteers
- 62 people
- Sponsor
- Luis Monteiro
Periodontitis, Peri-implant Mucositis
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant…
- Conditions
- Periodontitis, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT05834946
- Testing
- Megagen implant placement, Biomate-Swiss implant
- Where
- Malaysia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Peri-implant Mucositis, Peri-Implantitis
Monitoring of Non-Surgical Treatment of Peri-implantitis
This study aimed to investigate the response to non-surgical treatment of peri-implantitis diseases during the maintenance phase.
- Trial name
- NCT06408467
- Testing
- aMMP-8 diagnostic test
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lahanna oy
Implant Complication, Peri-Implantitis
Prediction of Failure of Dental Implants
The aim of the study is to identify predictors in patient profiles and implant characteristics and to develop and calibrate a prediction model for failure of implants.
- Trial name
- NCT04129957
- Testing
- Placement of dental implants
- Where
- Netherlands
- Volunteers
- 337 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam