Clinical trials: Penis/Surgery
Analgesia
Analgesia for Perineal Surgeries in High-risk Pediatric Patients
Perioperative pain management in pediatric patients, especially for anorectal and penile surgeries, presents significant challenges for anesthetists.
- Trial name
- NCT07602894
- Testing
- Systemic analgesia, Sacral multifidus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Penile Cancer, Lymph Node Metastasis
Inguinal Lymphadenectomy for Penile Cancer
The aim of the present study is to prospectively compare oncological and functional results of penile radical inguinal lymphadenectomy performed with an open versus videolaparoscopic technique.
- Conditions
- Penile Cancer, Lymph Node Metastasis, Sentinel Lymph Node, Surgical Complication
- Trial name
- NCT05887921
- Testing
- Inguinal Lymphadenectomy
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Penile Implant
A Study on the Safety and Effectiveness of Subcutaneous Silicone Penile Implant Surgery
This study will identify a patient population who wishes to address a variety of concerns about the size, shape, or appearance of their penis with the placement of a subcutaneous Silicone Block Penile Implant.
- Trial name
- NCT04985123
- Testing
- Pre-Formed Penile Silicone Block Implant
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Medical Devices, Inc.
Elective Circumcision Surgery
A Comparison of the Efficacy of Sacral Erector Spinae Plane Block and Penile Block in Circumcision Surgery
Effective perioperative analgesia is crucial for reducing hospital stay in pediatric surgical patients. Opioid-based analgesia, although effective, may lead to respiratory depression in the postoperative period.
- Trial name
- SACRAL ESP (NCT07097844)
- Testing
- 0.8 mL/kg of 0.25% bupivacaine
- Volunteers
- 62 people
- Sponsor
- Siirt Training and Research Hospital
Transsexualism, Surgery
Use of an External Erectile Device in Transgender Man Following Phalloplasty
The purpose of this study is to test whether an external erectile prosthesis (The Elator™) is a feasible alternative to internal erectile prostheses for transgender men who have undergone a phalloplasty with glansplasty and wish…
- Conditions
- Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
- Trial name
- ProstHEsis (NCT03823014)
- Testing
- Elator
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pain
Pudendal Block Versus Caudal Block for Hypospadias
The aim of this prospective randomized study is to assess the analgesic efficacy and duration of Pudendal block compared with Caudal block for pediatric patients undergoing hypospadias surgery concerning intraoperative analgesic…
- Trial name
- NCT02390388
- Testing
- pudendal nerve block, caudal block
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Postoperative Care, Analgesia Assessment
Posthectomy in Pediatric Elective Surgery : a Comparison of Perioperative Analgesia Using Echo-guided Penile Block and Pudendal Block With neurostimuLation Technique
Context : Posthectomy is a surgical procedure that concerns around 30% of the male population, mainly in pediatrics. As this procedure is mainly performed on an outpatient basis, the implementation of an enhanced rehabilitation…
- Conditions
- Postoperative Care, Analgesia Assessment, Posthectomy, Postoperative Analgesia
- Trial name
- PinEAPPLE (NCT07191938)
- Testing
- Ultrasound guided penile block, Neurostimulation guided pudendal block
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Caen
Erection; Incomplete
Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery
Penile erection is an unwanted event in transurethral (through the urethra) surgeries, which may be associated with adverse outcomes such as impaired access, prolonged operation time, the need to abort the operation, or the…
- Trial name
- PENIS (NCT06378645)
- Testing
- General Anesthesia: Propofol, General Anesthesia: Sevoflurane
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Etienne Xavier Keller
Elective Penile Surgeries, Hypospadias
Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery
Caudal block is often performed to relieve postoperative pain in pediatric urological surgery. Recently, pudendal block is also used in penile surgery and it has advantage because of less side effects such as transient weakness…
- Conditions
- Elective Penile Surgeries, Hypospadias, Urethral Fistula or Stricture After Hypospadias Repair, Penile Curvature
- Trial name
- NCT02848157
- Testing
- Dexmedetomidine, plain ropivacaine, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Circumcision, Ultrasound
Compared Reversed US-Guided Dorsal Penile Nerve Block (RUSDPNB) With DPNB in Circumcisions for Pediatric Patients
Circumcision is a widely performed surgical procedure. For this reason, optimal analgesic management is essential. Loco-regional anesthesia, particularly penile blocks, combined with general anesthesia is the technique of choice…
- Conditions
- Circumcision, Ultrasound, Opioid Consumption, Penile Surgery
- Trial name
- CIRCUSPRO (NCT06706375)
- Testing
- Using ultrasound for penile nerve block, Dorsal Penile Block Anesthesia using landmarks
- Where
- Switzerland
- Volunteers
- 216 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Peyronie's Disease
Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's
The purpose of this study is to compare key clinical outcomes of collagenase clostridium histolyticum injections versus surgery for the management of Peyronie's Disease.
- Trial name
- iSCRIP (NCT04786106)
- Testing
- Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH), Penile Plication Surgery, Incision and Grafting (I&G) Surgery
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Prostate Carcinoma, Erectile Function
Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers
This prospective randomized controlled trial (RCT) is designed to provide high level evidence on the efficacy of Low-intensity Extracorporeal Shock Wave Therapy (Li-ESWT) in the treatment of post-Robot-Assisted (RA) Radical…
- Conditions
- Prostate Carcinoma, Erectile Function, Genito Urinary Cancer
- Trial name
- RCT_LiESWT (NCT06717711)
- Testing
- Low-intensity Extracorporeal Shock Wave Therapy (LiESWT), PDE5 inhibitor (tadalafil)
- Where
- 2 sites in Italy
- Volunteers
- 158 people
- Sponsor
- Regina Elena Cancer Institute
Caudal Block, Pediatric Urologic Surgeries
Comparison of Caudal Block Combined With General Anesthesia and Penile Block and Intravenous Fentanyl in Pediatric Surgeries
Urogenital surgery is one of the most frequently performed surgical procedures in the pediatric patient population. There is no consensus on which analgesic method is most effective for pain control in these patients.
- Conditions
- Caudal Block, Pediatric Urologic Surgeries, Fentanyl, Pediatric Delirium
- Trial name
- NCT06862271
- Testing
- Group 1 ( Caudal block group ), Group 2 (Penile block and IV Fentanyl group)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Miray Gözde Özdemir
Surgery for Sacral Nerve Neurostimulation, Surgery for Urinary Artificial Sphincter
Medico-economical Evaluation of Patient-hotel in Urology
This is a medico-economic study of outpatient surgery paired with a night stay in a patient-hotel, compared with a conventional hospitalization for three types of urological surgeries.
- Conditions
- Surgery for Sacral Nerve Neurostimulation, Surgery for Urinary Artificial Sphincter, Surgery for Prosthetic Penile Implant
- Trial name
- HOTELAMBU (NCT02890017)
- Testing
- postoperative hotel, conventional hospitalization
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Regional Anesthesia, Hypospadias
Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery
Hypospadias repair is a urological surgical operation that is very painful in the postoperative period and requires long-term analgesia.
- Trial name
- NCT04668183
- Testing
- Pudendal nerve block group, Dorsal penile nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Postoperative Pain, Hypospadias
Comparison of Sacral ESP Block and Dorsal Penile Nerve Block in Pediatric Hypospadias Surgery
This randomized controlled trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Sacral Erector Spinae Plane (ESP) block versus Dorsal Penile Nerve Block (DPNB) in pediatric patients aged 1-7 years…
- Trial name
- NCT07426731
- Testing
- Sacral ESP Block Group, Dorsal Penile Nerve Block Group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medipol University
Tramadol - Anesthetics- Child - Circumcision
Tramadol in Penial Block Does it Improve Efficiency of Postoperative Analgesia in Circumcision
After the consent of the local ethics committee and informed consent of the parents, we conducted a prospective randomized, double-blind study, from 30 June 2014 to 31 December 2014, including one to eight year olds, ASA I or II…
- Trial name
- NCT03260439
- Testing
- Tramadol
- Where
- Tunisia
- Volunteers
- 106 people
- Sponsor
- Leila mansali stambouli
Hypospadias
Analgesia in Pediatric Hypospadias Surgeries
The primary aim of the current study will be to use the duration until the first postoperative analgesic requirement after two different block techniques to compare the analgesic effect.
- Trial name
- NCT06410482
- Testing
- US guided caudal block, Dorsal penile nerve block
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assiut University
Penis/Surgery, Penis/Injuries
Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction
The goal of this randomized interventional clinical trial is to learn if placement of a thin layer of fatty tissue (fat graft) beneath a split-thickness skin graft on the surface of the penis improved outcomes of surgery in men…
- Conditions
- Penis/Surgery, Penis/Injuries, Penile Skin, Adult-Acquired Buried Penis
- Trial name
- NCT07316491
- Testing
- Autologous fat grafting, Genitourinary Reconstruction with Split-Thickness Skin Grafting
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh