Clinical trials: Pediatric Cataract
Congenital Cataract, Aphakic or Pseudophakic Glaucoma
Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients
In cell cultures, lens epithelial cells and trabecular meshwork cells will be exposed to aqueous humor from pediatric eyes undergoing cataract removal surgery.
- Trial name
- NCT01136473
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Carmel Medical Center
Cataract
An Interocular Comparative Study of Unilateral Cataract
The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to…
- Trial name
- NCT02765230
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
Inflammation
Clinical Trial on Anti-inflammatory Effect of Low-Molecular Weight Heparin in Pediatric Cataract Surgery
The purpose of this study is to determine if intraocular infusion of low-molecular weight heparin (enoxaparin) influences postoperative inflammation following pediatric cataract surgery with intraocular lens (IOL) implantation.
- Trial name
- NCT00986076
- Testing
- Enoxaparin, Balanced Salt Solution
- Where
- India
- Volunteers
- 23 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia in Children
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
- Trial name
- NCT01547442
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 19 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Cataract
Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
- Trial name
- NCT05191706
- Testing
- Dexamethasone, Prednisolone Acetate Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 17 people
- Sponsor
- EyePoint Pharmaceuticals, Inc.
Glaucoma Following Pediatric Cataract Surgery
Outcome of Gonioscopy-Assisted Transluminal Trabeculotomy in Pediatric Glaucoma Following Cataract Surgery.
This prospective case series evaluated the 12-month outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in children with glaucoma following cataract surgery (GFCS).
- Trial name
- (GATT in GFCS) (NCT07542522)
- Testing
- gonioscopy assissted transluminal trabeculotomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Traumatic Cataract
Long-term Visual and Refractive Outcomes After Traumatic Cataract Surgery in Children
This prospective multicenter observational study aims to evaluate long-term visual and ocular biometric outcomes in pediatric patients aged 0-16 years who were diagnosed with traumatic cataract and underwent cataract extraction…
- Trial name
- NCT07087275
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jin Yang
Cataract
A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract
To assess the safety of Dextenza compared to an active control, prednisolone acetate suspension, for the treatment of postoperative pain and inflammation following ocular surgery for pediatric cataract.
- Trial name
- NCT04539548
- Testing
- Dextenza Ophthalmic Insert, Prednisolone acetate ophthalmic suspension USP 1%
- Where
- 14 sites in United States
- Volunteers
- 65 people
- Sponsor
- Ocular Therapeutix, Inc.
Cataract, Pediatric Cataract
AquaLase Capsule Wash for Pediatric Eyes
To determine whether AquaLase capsule wash reduces posterior capsule opacification (PCO) in pediatric eyes.
- Trial name
- NCT00756327
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Pediatric Cataract, Congenital Cataract
New Technique in Congenital/Pediatric Cataract Surgery
In pediatric/congenital cataract surgery; multiple surgical interventions are performed, which needs multiple general anesthesias. Here, we describe a new technique, to end the operation in one session.
- Trial name
- NCT05278936
- Testing
- The cataract surgery and the anterior vitrectomy
- Where
- Iraq
- Volunteers
- 52 people
- Sponsor
- Omer Othman Abdullah
Ventilation, Laryngeal Mask Airway
Impact of Different Modes of Ventilation With Laryngeal Mask Airway on Pediatric Cataract Surgery
This study will be conducted to evaluate effects of different modes of ventilation on pediatric cataract surgery aiming to a peri-operative stable anesthesia, better surgical satisfaction and post operative recovery.
- Conditions
- Ventilation, Laryngeal Mask Airway, Cataract Surgery
- Trial name
- NCT04241653
- Testing
- Pressure Support Ventilation, Unparalyzed Pressure Control Ventilation, Paralyzed Pressure Control Ventilation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sameh Fathy
Pediatric Cataract, Congenital Cataract
Shanghai Pediatric Cataract Study
The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of pediatric cataract participants, including congenital and traumatic cataract.
- Conditions
- Pediatric Cataract, Congenital Cataract, Traumatic Cataract, Visual Outcome
- Trial name
- NCT03063216
- Testing
- intraocular lens implantation
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Evidence Based Cataract Study Group
Endophthalmitis, Cataracts Infantile
Nylon Verus Polyglactin Corneal Suture in Pediatric Cataract Surgery
Pediatric cataract surgery requires the suturing of the corneal incision in order to maintain the integrity of the eyeball and to help avoid the trauma often caused by scratching in the postoperative period of pediatric…
- Conditions
- Endophthalmitis, Cataracts Infantile, Suture, Complication
- Trial name
- NCT03812640
- Testing
- Vicryl suture, Nylon suture
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Cataracts Infantile
Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population
Multicenter, randomized, evaluator-blinded clinical trial compared to Prednisolone acetate, 1% in the treatment of inflammation and pain after cataract surgery in pediatric population.
- Trial name
- CLOSE-3 (NCT05724446)
- Testing
- Clobetasol Propionate, Prednisolone acetate ophthalmic suspension, 1%
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Salvat
Congenital Cataract
Iridocorneal Angle and Anterior Segment Structure in Eyes of Children With Cataract
The aim of this study is to evaluate the morphology of iridocorneal angle and anterior segment structure in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- ACA (NCT03778086)
- Testing
- gonioscopy
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Contrast Sensitivity
Contrast Sensitivity Assessment in Pediatric Cataract Surgery With IOL Implantation
The study evaluates contrast sensitivity in older children following surgery for lamellar and posterior subcapsular cataracts. Often, pediatric surgeons tend to delay surgery in these children who present beyond the amblyogenic…
- Trial name
- NCT01901744
- Testing
- Cataract Surgery
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
Evaluation of Therapeutic Strategies in Pediatric Cataract Surgery
The purpose of this observational study is to assess the therapeutic strategies in the treatment of pediatric cataracts.
- Trial name
- EP3C (NCT02253017)
- Testing
- Children operated on for cataract
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Glaucoma Following Pediatric Cataract Surgery, Glaucoma Secondary
Glaucoma Following Pediatric Cataract Surgery
The purpose of this study is to report the incidence and related risk factors glaucoma following cataract surgery (GFCS). and to provide evidence-based evidence for the development of standardized follow-up methods or diagnosis…
- Conditions
- Glaucoma Following Pediatric Cataract Surgery, Glaucoma Secondary, Congenital Cataract
- Trial name
- NCT05451745
- Volunteers
- 819 people
- Sponsor
- Sun Yat-sen University