Clinical trials: Pectus Deformity of Chest
Pain, Pain, Postoperative
Prediction and Characterization of Acute and Chronic Postoperative Pain
Despite enormous progress insufficient postoperative pain management remains a frequent problem in the early postoperative phase after surgery.
- Conditions
- Pain, Pain, Postoperative, Funnel Chest
- Trial name
- NCT01308385
- Testing
- Conditioned pain modulation
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Pectus Excavatum
The Effect of Patient Position on the External Haller Index Value Among Patients With Pectus Excavatum
Pectus excavatum is the most common anterior chest wall deformity, affecting up to 1:400 of newborns. The current gold standard to quantify the extent of deformity is by calculating the Haller Index based on a Computed Tomography…
- Trial name
- POSITION (NCT04046835)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Pectus Excavatum, Pectus Excavatum Deformity
The Effects of Schroth Based Exercise Therapy in Adolescents with Pectus Excavatum
Research on exercise methods for pectus excavatum (PE) is limited, highlighting the need for further studies. This study investigated the effects of Schroth-based exercise therapy combined with vacuum treatment in 35 adolescents…
- Conditions
- Pectus Excavatum, Pectus Excavatum Deformity, Funnel Chest, Chest Deformities
- Trial name
- NCT06763406
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Hacettepe University
Pectus Excavatum, Pain, Postoperative
Identification of Best Postoperative Analgesia Method Following a Minimally Invasive Repair of Pectus Excavatum
Pectus excavatum is the most common chest wall deformity in children, accounting for 90% of all congenital chest wall deformities. It occurs in one to eight per 1000 live births.
- Trial name
- (MIRPE) (NCT04211935)
- Testing
- Use of PCA, Use of ESB for postoperative pain control after MIRPE, Use of INC for postoperative pain control after MIRPE
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pectus Excavatum, Pain, Postoperative
Sub-Paraspinal Block in Nuss Patients. A Pilot Project
The purpose of this pilot study was to evaluate effectiveness of a novel regional anesthesia technique developed at the investigators institution, as part of a quality improvement initiative, to assist with multilevel thoracic…
- Trial name
- NCT02169297
- Testing
- Ultrasound-guided Sub-Paraspinal Block, PCA only
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Pectus Excavatum
Quantifying Changes in the Thoracic Wall After Nuss Bar Removal in Pectus Excavatum Patients Using 3D Imaging
Pectus excavatum (funnel chest) is the most common congenital anterior thoracic wall deformity. It can be associated not only with cosmetic concerns but also with psychosocial and limiting somatic complaints.
- Trial name
- CHEST (NCT07498699)
- Where
- Netherlands
- Volunteers
- 69 people
- Sponsor
- Erik de Loos
Pectus Carinatum, Chondromanubrial
Chest Compressor for Conservative Treatment of Pectus Carinatum: a Multicenter Study
Pectus carinatum (PC) is a congenital deformity of the chest wall whose prevalence is 0.6% of the population and although it does not cause cardio respiratory physiological damage, it has profound psychological effects on young…
- Trial name
- NCT04171063
- Testing
- Thoracic compressor
- Where
- 4 sites in Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Deformity of Chest Wall
SPAIN Chest Wall Deformity Project (Pectus Repair)
Context: Chest wall deformities in children are relatively common. One such deformity, known as Pectus Excavatum (PE), involves a concavity of the chest and is the most frequent of these abnormalities - present in approximately 1…
- Trial name
- NCT02098681
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Boston Children's Hospital
Pectus Excavatum
Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum
This study is a Phase 3, multicenter, non-randomized study to evaluate the safety and efficacy of the next-generation outpatient Magnetic Mini-Mover Procedure (3MP) in 15 patients aged 8-14 years for the correction of pectus…
- Trial name
- 3MP (NCT01327274)
- Testing
- Magnetic Mini-Mover Procedure (Magnimplant)
- Where
- 3 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Harrison
Pectus Excavatum
Effects of Exercise Therapy on Pectus Excavatum
Pectus excavatum (PE); It is an anterior chest wall deformity, characterized by varying degrees of depression of the sternum and costal cartilage, usually occurring at birth or in the first year of life.
- Trial name
- NCT04167865
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Acibadem University
Pectus Deformity, Physical Disability
Comparison of Physical and Psychosocial Characteristics of Pectus Excavatum and Carinatum Patients With Healthy Controls
Chest wall deformities are the development of ribs, cartilage and sternum that form the chest wall together with isolated or abnormalities of the musculoskeletal system. Pectus excavatum and carinatum deformities are most common.
- Conditions
- Pectus Deformity, Physical Disability, Psychosocial Impairment
- Trial name
- NCT04172142
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pectus Excavatum, Pectus Carinatum
Chest Wall Deformities Beyond the Chest Wall
Pectus excavatum (PE) and pectus carinatum (PC) are chest wall deformities that may influence respiratory function, physical capacity, posture, and quality of life.
- Trial name
- BEYOND (NCT07844382)
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Funnel Chest, Excavatum, Pectus
Cryoanalgesia Aplication Time Optimization During Nuss Procedure
This study compared standard therapy (multimodal analgesia with 2 minutes cryoanalgesia) versus a novel approach (multimodal analgesia with 1 minute cryoanalgesia) in subject undergoing minimal invasive modyfied Nuss procedure…
- Trial name
- NCT05831137
- Testing
- shorter cryoanalgesia
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Juvenile Idiopathic Arthritis (JIA), Fibromyalgia
Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain
The purpose of the study is to discover the underlying subtypes of chronic musculoskeletal pain (muscle and joint pain) in youth.
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis
- Trial name
- BRIDGE Pain (NCT07602595)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Pectus Excavatum
Comparative Analysis Of Modified Vs. Classical Nuss Technique In The Surgical Correction Of Pectus Excavatum "
Although the NUSS technique has become the standard minimally invasive procedure for correcting this deformity, there is a lack of comparative data between the classic and modified NUSS techniques.
- Trial name
- PE (NCT07312448)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Pectus Excavatum Deformity
Treatment of Pectus Excavatum Deformity Using Macrolane Filler
This is a prospective, open, non-comparative and baseline-controlled study to evaluate efficacy and safety of Macrolane VRF20 treatment in 40 subjects with pectus excavatum deformity.
- Trial name
- NCT01750112
- Testing
- Macrolane VRF20
- Where
- 2 sites in France, Sweden
- Volunteers
- 23 people
- Sponsor
- Galderma R&D
Pain
Preemptive Genotyping and Pain Management
The purpose of this study is to see if testing for genes related to pain and pain management before surgery affects how patients are treated for pain after surgery.
- Trial name
- NCT01813695
- Testing
- Preemptive genotyping in medical record, Genotyping not included in electronic medical record
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati