Clinical trials: Patient Preference, open to volunteers
Informed Consent, Preference, Patient
Patient Preferences on Same-day Bilateral Intravitreal Dexamethasone Injections
Intravitreal injections with dexamethasone implant (Ozurdex®) provide a reasonable and long-lasting treatment option in the cases of diabetic macular edema, as well as macular edema resulting from retinal vein occlusion and…
- Trial name
- NCT06894017
- Testing
- Ozurdex (dexamethasone)
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Actinic Keratosis (AK)
Outcomes Associated With Tirbanibulin for Large Field Application on the Face in the U.S (CLEAR)
The goal of this observational study is to learn about the effectiveness of tirbanibulin among adult subjects with actinic keratosis (AK) lesions in the face.
- Trial name
- CLEAR (NCT07657988)
- Testing
- Tirbanibulin
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Avant Health LLC
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
Lung Carcinoma, Metastatic Lung Carcinoma
Novel INPUT Screening Tool to Improve Illness Understanding in Patients With Metastatic or Incurable Lung Cancer
This clinical trial compares the use of a new screening tool designed to evaluate patients' information needs, preferences, and illness understanding to the usual care to improve illness understanding in patients with lung cancer…
- Conditions
- Lung Carcinoma, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8
- Trial name
- NCT06743308
- Testing
- Best Practice, Questionnaire Administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Patient Preference
CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve
Fractional flow reserve (FFR)-guided PCI for chronic coronary syndromes (CCS) is reported to improve the outcomes compared with angiography-guided PCI.
- Trial name
- CAPTURE (NCT06508697)
- Testing
- invasive coronary angiography (ICA) with fractional flow reserve (FFR) pressure measurement
- Where
- Japan
- Volunteers
- 400 people
- Sponsor
- Fujita Health University
Hip Osteoarthritis
MOVE-HIP: Ceramic Hip Resurfacing Versus Total Hip Arthroplasty Using Activity Monitoring
MOVE-HIP is a pragmatic, multicenter randomized clinical trial comparing ceramic hip resurfacing arthroplasty with contemporary total hip arthroplasty in adults with symptomatic hip osteoarthritis who are considered clinically…
- Trial name
- MOVE-HIP (NCT07839403)
- Testing
- Ceramic-on-Ceramic Hip Resurfacing Arthroplasty, Contemporary Total Hip Arthroplasty
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Danderyd Hospital
Cancer, Sarcopenia
Personalized Cooking and Nutrition Guidance and Physical Activities Program to Reduce Muscle Loss in Advanced Cancer
People with advanced cancer often lose muscle over time. This can make them weaker, more tired, and reduce their quality of life. Many patients also struggle to eat because of changes in taste, smell, or appetite.
- Conditions
- Cancer, Sarcopenia, Muscle Mass Loss
- Trial name
- NCT07466862
- Testing
- Oncology Dietitian's Standard of Care, Personalized Culinary and Nutrition Therapy
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Gali Perel
Pedophilia, Hebephilia
Talking for Change: Secondary Prevention of Child Sexual Abuse Perpetration
The goal of this patient preference randomized controlled trial is to investigate the efficacy of Talking for Change (TFC), an intervention for the secondary prevention of child sexual abuse and exploitation (CSA) perpetration.
- Conditions
- Pedophilia, Hebephilia, Child Sexual Abuse, Program Evaluation
- Trial name
- NCT07001735
- Testing
- Talking for Change Group Psychotherapy, Healthier Me: Managing Risk and Stress in Everyday Life
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Goals of Care, Patient Preference
Eliciting Informed Goals of Care in Elderly Patients
Patient-centered medical care considers a patient's values and goals for their health and well-being. Healthcare providers use this information to formulate a medical care plan that is aligned with these expectations.
- Conditions
- Goals of Care, Patient Preference, End of Life
- Trial name
- ASKMEGOC (NCT06002113)
- Testing
- GOCD Tool, Usual care
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Royal Victoria Hospital, Canada
Breast Cancer Metastatic, Advanced Breast Cancer
Decision Support Tool for Patients With Advanced Breast Cancer
The goal of this pilot study is to understand and improve the shared decision-making process between people with advanced breast cancer and their providers regarding their care and treatment.
- Conditions
- Breast Cancer Metastatic, Advanced Breast Cancer, Stage 4 Breast Cancer, Stage IV (Metastatic) Breast Cancer
- Trial name
- COAST (NCT07635147)
- Testing
- Decision Support Tool
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Weill Medical College of Cornell University
Objective Pain and Discomfort, Subjective Pain and Discomfort
The Effect of Virtual Reality Distraction on Pain and Discomfort Associated With Bitewing Radiographs in Pediatric Patients
This study will be conducted at King Abdulaziz University Dental Hospital (KAUDH). Ethical approval was obtained from the Research Ethics Committee of the Faculty of Dentistry at King Abdulaziz University (32-03-25).
- Conditions
- Objective Pain and Discomfort, Subjective Pain and Discomfort, Behavior, Satisfaction
- Trial name
- NCT07376941
- Testing
- virtual reality device goggles
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Bleeding, Platelets
Autologous Cold-stored Apheresis Platelets
The Auto-PLTS Study is a single-centre trial performed at Toronto General Hospital (TGH) that uses a randomized, patient preference design.
- Conditions
- Bleeding, Platelets, Cardiopulmonary Bypass, Cardiac Surgery
- Trial name
- Auto-PLTS (NCT07064954)
- Testing
- Autologous Cold-Stored Platelets, Allogeneic Room Temperature-Stored Platelets (Standard of Care)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Primary Care Patients, Primary Care Provider
Evaluating the Preferences and Tradeoffs of AI-based Electronic Consultations for Older Adults in Primary Care
Electronic consultations, or e-consults, let a primary care doctor request medical advice from a specialist without requiring the patient to attend a separate visit.
- Trial name
- NCT07766694
- Testing
- Discrete Choice Experiment Survey
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Pennsylvania
Acute Stroke
Factors and Preferences in Patient Selection of Rehabilitation Care Following Acute Stroke: A Predictive Correlational Study.
Background and Purpose Patients with stroke have to receive the rehabilitation care after medical condition has stabilized. In recent years, the long-term care policy offers more options available for rehabilitation care after…
- Trial name
- NCT07089095
- Testing
- questionnaire
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
HIV Pre-exposure Prophylaxis
Long-Acting Injectable HIV PrEP PROs
The goal of this observational study is to learn about the real world effectiveness, patient satisfaction and clinical outcomes of LAI PrEP with lenacapavir (LEN) versus cabotegravir (CAB) through surveys and interviews.
- Trial name
- IMPACT (NCT07379658)
- Testing
- Interview and survey to evaluate patient reported outcomes between the two medications.
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- Anupama Raghuram MD
Family Members, Critical Illness
The VIP3 (Very Old Intensive Care Patients) Study: Family Involvement in Treatment Decisions for Old ICU Patients
The demographics of the global population is changing with increasing numbers of elderly and co-morbid patients. As a result, more elderly patients will be admitted to the Intensive Care Unit (ICU), which will bring several…
- Conditions
- Family Members, Critical Illness, Frailty, Communication
- Trial name
- VIP3 (NCT07035951)
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- St George's, University of London
Obstructive Sleep Apnea
Comparative Assessment of Sleep Positive Airway Pressure Modalities (CASPAM)
Obstructive sleep apnea (OSA) has been one of the topmost global health problems. It is an underdiagnosed disease which have a huge burden on healthcare if left untreated.
- Trial name
- CASPAM (NCT06564896)
- Testing
- CPAP Airsense 10 vs Air-Mini
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- National University of Malaysia
Lung Cancer, Quality of Life
Improvement of Quality of Life (QoL) Using Preference-Oriented QoLMonitoring in Patients with Lung Cancer
The purpose of the study is to determine whether a preference-oriented quality of life monitoring with defined diagnostic and therapeutic options improves quality of life in patients with lung cancer during routine follow-up care.
- Trial name
- LePaLuMo (NCT06252233)
- Testing
- patient- and physician-centered QoL monitoring
- Where
- 8 sites in Germany
- Volunteers
- 220 people
- Sponsor
- University of Bayreuth
Generalized Anxiety Disorder (GAD)
The Effect of Patient Preference for Treatment Model in Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder
The goal of this clinical trial is to investigate the effect of allowing patients to choose between two internet-based cognitive behavioral treatments (ICBT) for generalized anxiety disorder (GAD).
- Trial name
- ORIGAMI (NCT07201844)
- Testing
- Metacognitive Internet delivered Cognitive Behavior Therapy, Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Persistent Spinal Pain Syndrome
Patient Preference and Long-term Outcomes in Persistent Spinal Pain Syndrome: A Prospective Study Comparing Spinal Cord Stimulation to Intrathecal Drug Delivery.
Spinal cord stimulation (SCS) or intrathecal drug delivery (pain pump) can be effective in providing pain relief for patients with low back pain who have not responded to other treatments.
- Trial name
- NCT07091123
- Testing
- Pain pump, Bupivacain 0.625%/Fentanyl 2mcg/ml, Spinal Cord Stimulator (SCS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center