Clinical trials: Pathological Fracture
Elbow Pain, Supracondylar Humerus Fracture
The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures
The goal of this intervention trial is to learn if a ultrasound diagnosis of elbow fractures can improve care in pediatric patients seen in the emergency room.
- Conditions
- Elbow Pain, Supracondylar Humerus Fracture, Radial Head Fractures, Radial Head or Neck Fractures
- Trial name
- NCT07212036
- Testing
- Ultrasound of the elbow, X-ray of elbow
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postoperative Blood Loss
Effect of Early Administration of TXA in Adult Hip Fractures
This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center.
- Trial name
- NCT05047133
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Weight Loss, Bone Density
The Effect of Weight Loss and Dietary Protein Intake on Bone
The purpose of this study is to learn how the amount of protein during moderate weight loss influences bone health. We will also examine how two levels of protein intake affects diet quality.
- Trial name
- NCT00473031
- Testing
- Caloric restriction, high protein, Caloric restriction; normal protein, Counseling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Cardiovascular Diseases, Non-communicable Disease
Effects of Primary Prevention in Elderly People-The Healthy Aging Initiative
The number of elderly will increase rapidly in Europe in the next 30 years, which affects the country's economic and social development, welfare, health care, and also the individuals.
- Trial name
- HAI (NCT03312439)
- Testing
- Given advice
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Region Västerbotten
Clavicle Fracture
Supraclavicular Nerve During Clavicle ORIF
Clavicle fractures are a common orthopedic injury and make up 2.6%-5% of all fractures. Despite the benefits of operative management, post-operative chest wall paresthesia is a well-known complication among surgeons and is well…
- Trial name
- NCT06050473
- Testing
- Nerve-sacrificing procedure, Nerve preserving procedure
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Analgesia, Pain, Acute
Duration of Analgesia With Dexmedetomidine and Ropivacaine in Brachial Plexus Block
This is a prospective, randomized, double blind study of adding dexmedetomidine to ropivacaine for Brachial plexus block and assessing the analgesia with VAS pain scales(0-10), Satisfaction scale by VAS scale(0-10) and time to…
- Conditions
- Analgesia, Pain, Acute, Peripheral Nerve Block
- Trial name
- NCT03385967
- Testing
- Dexmedetomidine, ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Pain, Postoperative
Split Scripts for Pediatric Supracondylar Fracture Repairs
This study is designed to test the hypothesis that increased electronic order-set compliance and focused education will decrease the amount of unconsumed opioid entering and remaining in the home after pediatric supracondylar…
- Trial name
- NCT05372133
- Testing
- Morphine
- Where
- Canada
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Arthroscopic Knee Surgery, Lower Limb Fractures
Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes
This study compares the gait pattern of individuals with weight bearing difficulties walking on the floor, a soft surface, or with special shoes (Kyboot).
- Conditions
- Arthroscopic Knee Surgery, Lower Limb Fractures, Back Pain and Asymmetric Gait, Complex Regional Pain Syndrome
- Trial name
- NCT02742376
- Testing
- Soft surface, Floor, Kyboot shoes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Postoperative Delirium
Study of Postoperative Delirium in Elderly People After Orthopedic Surgery
The purpose of this study is to investigate the possible relationship of microRNA and postoperative delirium.
- Trial name
- NCT02817386
- Testing
- interview
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Tibial Fractures, Fibula Fracture
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a repair mechanism in chronic…
- Conditions
- Tibial Fractures, Fibula Fracture, Knee Fracture
- Trial name
- NCT05317676
- Testing
- Palmitoylethanolamide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Fractures
Influence of External Factors on Skeletal Growth in Youth
Objective: Prospective study regulation in bone mass, size, architecture, cortical, trabecular bone, soft tissues and risk factors for cardiovascular disease at growth. Determine regulation by environmental factors.
- Trial name
- NCT00633828
- Testing
- Increased physical education in primary school (daily)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Gastroparesis, Hip Fracture
Gastric Emptying in Elderly With Hip Fracture
The gastric emptying of 400 ml 12.6% carbohydrate rich drink is investigated in elderly women, age 75-100, with acute hip fracture.
- Conditions
- Gastroparesis, Hip Fracture, Mild Insufficient Nutrition
- Trial name
- GASEMPHIP (NCT02753010)
- Testing
- Gastric emptying of carbohydrate-rich beverage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Emergency Service, Hospital, Child/Adolescent Problem
A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
MSK-I is the most common cause for ED visits for children with pain, with a child's risk of sustaining a fracture ranging from 27-42% by the age of 16 years.
- Conditions
- Emergency Service, Hospital, Child/Adolescent Problem, Acute Pain, Fentanyl
- Trial name
- CAST (NCT02985177)
- Testing
- INF2.0 + IBU, INF1.0 + IBU
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Pulmonary Disease, Chronic Obstructive, Osteoporosis
CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD
The goal of this translational study is to establish a newly emerging CT-based tool for the characterization of changes in bone micro-architecture and assessment of their implications for fracture-risk in a population of COPD…
- Trial name
- NCT03534934
- Testing
- Vital signs, Urine Pregnancy Test, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Punam K Saha
Supracondylar Fracture, Morbidity
Comparison of Day-time and Night-time Operations of Supracondylar Humeral Fractures
This study aims to investigate that performing supracondylar humerus fracture operations during daylight hours may have better results than performing them at night.
- Trial name
- NCT04694469
- Testing
- Closed reduction and percutaneous pinning (CRPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hip Fractures, Post Operative Pain
Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block
The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries
- Trial name
- NCT06294665
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Educational Problems, Simulation of Physical Illness
Learning Management of Open Fractures on Virtual Patient
A novel virtual world programme with over 240 multiple choice questions was developed to assess the competencies in managing an open fracture of the lower limb according to the British Orthopaedic Association Standards for Trauma…
- Conditions
- Educational Problems, Simulation of Physical Illness, Fractures, Bone, Emergencies
- Trial name
- NCT04605380
- Testing
- Virtual reality online world
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Stress Response, Multitasking Behavior
Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking?
This clinical trial aims to investigate the effects of a 70-day consumption of cranberry juice on cognitive and motor accuracy, mental and physiological stress, and stress response in healthy men and women between the ages of 30…
- Conditions
- Stress Response, Multitasking Behavior, Mental Stress, Physiological Stress
- Trial name
- NCT06066619
- Testing
- Cranberry Juice A, Cranberry Juice B
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Florida
Foot Fracture, Ankle Fractures
Use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Surgery
This is a Randomized controlled trial evaluating the effects of the use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Surgery The trial will randomize 60 patients into an…
- Conditions
- Foot Fracture, Ankle Fractures, Ankle Injuries, Foot Injuries and Disorders
- Trial name
- HemaClear (NCT04818775)
- Testing
- HemaClear, Pneumatic Tourniquet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital do Coracao