Clinical trials: Pathological Fracture
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Hip Fractures, Hip Fracture Pathologic
Endoprosthetic Replacement for Pathological Fractures of the Hip: A 35-year Update
This study will be based on a retrospective review of patients who received endoprosthetic reconstruction for pathologic fracture of the proximal femur.
- Conditions
- Hip Fractures, Hip Fracture Pathologic, Pathological Fracture, Pathological Fracture of Hip
- Trial name
- NCT06935071
- Testing
- Data Collection and Analysis
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Humerus Pathological Fracture
A Safety and Efficacy Study of the Treatment of Impending and Actual Pathological Fractures in the Humerus From Metastatic Bone Disease
The purpose of this study is to collect safety and performance data of the Photodynamic Bone Stabilization System (PBSS) when used for the treatment of painful impending and actual fractures of the humerus secondary to metastatic…
- Trial name
- NCT02373904
- Testing
- Photodynamic Bone Stabilization System
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 14 people
- Sponsor
- IlluminOss Medical, Inc.
Traumatic Fracture, Pathological Fracture
Device Global Registry for the IlluminOss Bone Stabilization System
This is a multi-center, observational patient registry. The primary objective of the study is to collect safety and performance data on the IlluminOss Device when used to provide stabilization and alignment for the treatment of…
- Trial name
- NCT05206981
- Testing
- IlluminOss Device
- Where
- 16 sites in United States, Germany
- Volunteers
- 300 people
- Sponsor
- IlluminOss Medical, Inc.
Bone Metastases, Pathological Fracture
Short Versus Long Intramedullary Nails in the Treatment of Proximal Femur Metastasis.
The goal of this interventional randomized controlled trial is to compare the clinical outcomes in treating extremities pathological fractures (fractures of limbs caused by metastatic tumors) or impending pathological fractures…
- Conditions
- Bone Metastases, Pathological Fracture, Pathological Fracture, Left Femur, Pathological Fracture, Right Femur
- Trial name
- NCT05969470
- Testing
- Internal fixation with short intramedullary nails, Internal fixation with long intramedullary nails
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Bone Metastases, Lower Extremity Fracture
External Beam Radiation Therapy Post Surgery in Patients With Lower Extremity Bone Metastases Randomized Efficacy Trial
The objective of the present study is to evaluate the effectiveness of post-operative radiation therapy in lower extremity bone metastases.
- Conditions
- Bone Metastases, Lower Extremity Fracture, Pathological Fracture, Impending Fracture
- Trial name
- EXPLORE (NCT04109937)
- Testing
- External beam radiation therapy
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Pathological Fracture of Vertebra Due to Secondary Osteoporosis (Disorder), Pathological Fracture of Vertebra Due to Neoplastic Disease (Disorder)
Xpede Clinical Study
The purpose of this clinical study is to confirm the efficacy and safety of the Kyphon®Xpede™ Bone Cement in human use in China.
- Trial name
- NCT03730207
- Testing
- Xpede™ Bone Cement, Mendec Spine Bone Cement
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Medtronic Spinal and Biologics
Metastatic Bone Tumor, Pathological Fracture
Length of the Femoral Stem in Arthroplasty Done for Patients With Proximal Femoral Metastatic Lesion
Proximal femoral metastatic disease is a common cause of morbidity and mortality in cancer patients.protecting the entire femur using long nail or long femoral stem was hypothesized to prevent future fracture.However we believe…
- Conditions
- Metastatic Bone Tumor, Pathological Fracture, Arthroplasty
- Trial name
- NCT04660591
- Testing
- femoral stem in hip arthroplasty
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Pathological Fracture of Hip, Bone Metastases
Evaluation of the Performance of Y-STRUT® Medical Device to Strengthen Pre-fractural Tumour-induced Lesions at the Level of the Proximal Femur
HIPPON 100 is a national, multicentre, prospective, retrospective, descriptive and non-interventional study, in patients having a Y-STRUT® medical device implanted to prevent a high risk of impending pathological fracture.
- Trial name
- NCT03579212
- Testing
- Y-STRUT® (Hyprevention, Pessac, France)
- Where
- 4 sites in France
- Volunteers
- 16 people
- Sponsor
- Hyprevention
Osteoporosis of Disuse With Current Pathological Fracture
Associations Analysis Between Lifestyle and Osteoporosis
A large-scale, community-based, cross-sectional study was conducted to evaluate the extent to which lifestyle was associated with osteoporosis among the Chinese population by using self-reported questionnaire methods.
- Trial name
- NCT02451397
- Where
- 2 sites in China
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Senile Osteoporosis With Current Pathological Fracture Lower Leg (Diagnosis)
Rare Variation and Remote Gene Regulation of Osteoporosis Related Phenotypes in Han Chinesse
Bone density is recognized as the most important factor to measure osteoporosis, and the prevalence of osteoporosis increases with age.
- Trial name
- NCT04129671
- Testing
- No intervention was applied
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bone Cyst Aneurysmal, Pathological Fracture
Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts
The efficacy of traditional therapeutic approaches for aneurysmal bone cysts (ABC), such as surgery, embolization, sclerotherapy and radiotherapy, are often compromised for lesions in axial skeletons and adolescents complicated…
- Conditions
- Bone Cyst Aneurysmal, Pathological Fracture, Recurrent Disease, Refractory Tumor
- Trial name
- Deno-ABC (NCT03415477)
- Testing
- Denosumab (Xgeva)
- Volunteers
- 6 people
- Sponsor
- Peking University People's Hospital
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Postmenopausal Osteoporosis With Pathological Fracture
Clinical Comparison of Efficacy and Safety of Two Teriparatide Formulations: Osteofortil and Forteo
The primary objective of this study is to compare efficacy and safety of two formulations of teriparatide 20 mcg/day plus calcium and vitamin D in postmenopausal women with osteoporosis.
- Trial name
- NCT01945788
- Testing
- Teriparatide (rDNA origin)
- Where
- Argentina
- Volunteers
- 110 people
- Sponsor
- Bio Sidus SA
Humeral Fractures, Pathological Fractures
Intramedullary Fixation of Humerus Fractures Without Intramedullary Reaming
The purpose of the study is to evaluate the safety and efficacy of the composite Nail - the Quantum interlocking intramedullary nailing system in the reduction of humeral fractures.
- Trial name
- NCT01087463
- Testing
- Quantum
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- N.M.B. Medical Applications Ltd
Humeral Fractures, Pathological Fractures
Intramedullary Fixation of Humerus Fractures
The purpose of the study is to evaluate the safety and efficacy of the composite Nail - the Quantum interlocking intramedullary nailing system in the reduction of humeral fractures.
- Trial name
- NCT01017289
- Testing
- Quantum
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- N.M.B. Medical Applications Ltd