Clinical trials: Passive Leg Raising
Artificial Heart Device User
Impact of Fluid and Passive Leg Raising on Cardiac Output in Patients Undergoing Cardiac Surgery
Left Ventricular Assist Device (LVAD) implantation is a common surgical procedure in patients with end-stage heart failure. Optimal fluid management is essential for adequate postoperative treatment.
- Trial name
- NCT03179033
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Body Fluid Retention, Impedance
Effect of Passive Leg Raising for Fluid Responsiveness
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- NCT02702544
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Hypovolemia
The Use of an External Ultrasound Fixator (ProbeFixR) on Intensive Care Patients
Study to assess the feasibility of an external ultrasound fixator (ProbeFix)
- Trial name
- Soundprobe (NCT03497754)
- Testing
- Probefix
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Rijnstate Hospital
Circulatory Failure
the Impact of Manual or Mechanical Ways to Perform PLR on the Accuracy of Evaluation of Fluid Responsiveness
Our goal was to study the impact of different ways to perform passive leg raising (PLR) on the accuracy of evaluation of fluid responsiveness.
- Trial name
- PLR (NCT06285331)
- Testing
- Automatic Bed, Manual
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Southeast University, China
Ischemic Heart Disease
Can Changes in Velocity Time Integral Serve as a Sensitive Indicator for Monitoring Changes in Stroke Volume ?
Hypothesis: A validated technique to measure cardiac output (CO) using echocardiography is to calculate stroke volume from the product of LVOT area and LVOT VTI and multiplying the product with heart rate ( CO = SV x H/R; SV =…
- Trial name
- NCT02292888
- Testing
- Passive Leg Raising (PLR) test
- Volunteers
- 50 people
- Sponsor
- Fortis Hospital, India
Circulatory Failure, Critical Illness
Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU
This prospective observational study evaluates whether monitoring changes in exhaled carbon dioxide (End-Tidal CO2 or EtCO2) during a "Passive Leg Raising" (PLR) test can reliably predict fluid responsiveness in critically ill…
- Conditions
- Circulatory Failure, Critical Illness, Hypovolemia
- Trial name
- NCT07304648
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir Katip Celebi University
Ischemic Heart Disease, Cardiac Valve Disease
Passive Leg Raising Test to Predict Hypotension During Induction of Anesthesia in Patients Undergoing Cardiac Surgery
Hypotension frequently occurs during anesthesia induction. Preload decrease by anesthetics was often considered as one of main causes for this hypotension. However, the studies on this topic have been lacking.
- Trial name
- NCT01144546
- Testing
- passive leg raising (45 degree leg elevation for 1-2 min)
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Seoul National University Hospital
Cesarean, Spinal Anesthesia
Prediction of Maternal Arterial Hypotension After Spinal Anesthesia by Passive Leg Raise Test.
Spinal anesthesia for cesarean section is associated with a high incidence of low blood pressure. However, the pathophysiology of this arterial hypotension is not unequivocal and could involve, in addition to drug vasoplegia, a…
- Trial name
- EDLIDL (NCT05133271)
- Testing
- Clinical hemodynamic and echocardiographic evaluation
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fluid Responsiveness
Prediction of Fluid Responsiveness From Passive Leg Raising Induced Changes in Perfusion Index and Pleth Variability Index
The aim of the study is to evaluate whether changes in Perfusion Index (PI) and Pleth Variability Index (PVI) during passive leg raising test can predict fluid responsiveness in spontaneously breathing patients.
- Trial name
- NCT03499860
- Testing
- Passive Leg Raising Test
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Institute of Mountain Emergency Medicine
Shock, Critical Illness
Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance
This study aims to evaluate the correlation between stroke volume measurements obtained by transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring.
- Trial name
- NCT07020637
- Testing
- Cheetah NICOM
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Nevada, Las Vegas
Preload-responsiveness
Is Mitral Velocity Time-integral a Marker of Preload-responsiveness in Patients With Acute Circulatory Failure?
The aim of this is to assess the reliability of the variability of the mitral velocity time-integral with passive leg raising to predict the fluid responsiveness in patients with acute circulatory failure in intensive care.
- Trial name
- NCT05538637
- Testing
- Echocardiography
- Where
- Morocco
- Volunteers
- 50 people
- Sponsor
- Avicenna Military Hospital
Cardiac Surgery
End-expiratory and End-inspiratory Occlusion Tests to Predict Fluid Responsiveness
The purpose of the study is to verify the efficacy of using end-expiratory and end-inspiratory occlusion tests as an index of fluid responsiveness in mechanically ventilated patients with cardiac surgery.
- Trial name
- EEOFR (NCT03485833)
- Testing
- EEO and EIO test
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Trendelenburg Maneuver, Passive Leg Raising
Trendelenburg Maneuver Versus Passive Leg Raising Test for Fluid Responsiveness in High-Risk Surgical Patients
The aim of this study is to evaluate whether Trendelenburg maneuver can be used to predict fluid responsiveness in high-risk surgical patients in intensive care unit as compared to Passive Leg Raising test.
- Conditions
- Trendelenburg Maneuver, Passive Leg Raising, High-Risk Surgical Patients
- Trial name
- NCT06423833
- Testing
- Trendelenburg maneuver (TM), Passive leg raising test
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Hypotension, Tachycardia
Passive Leg Raising Attenuates and Delays Tourniquet Deflation-induced Hypotension and Tachycardia
Background: The pneumatic tourniquet is frequently used in total knee arthroplasty. Tourniquet deflation may result in hypotension and tachycardia caused by the rapid shift of blood volume back to the ischemic limb and a decrease…
- Trial name
- NCT01592669
- Testing
- passive leg raising
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Circulatory Failure
Can Capillary Refill Time Variation During Passive Leg Raising Predict Fluid Responsiveness
Fluid responsiveness in a context of circulatory failure can be assessed by different way. Microcirculatory evaluation to assess fluid responsiveness could be interesting, but the available device are expensive and the analysis…
- Trial name
- NCT02248025
- Testing
- Observational study: No special intervention will be made.
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Hopital Louis Pradel
Septic Shock
Velocity Time Integral vs PICCO for Evaluation of Passive Leg Raising in Septic Shock
The objective of the present study is to investigate accuracy of changes in cardiac output following passive leg raising as estimated by transthoracic ultrasound as method to predict fluid responsiveness and compare that to…
- Trial name
- VIPS (NCT03621449)
- Where
- 2 sites in Sweden
- Sponsor
- Region Skane
Cardiac Surgery With Extracorporeal Circulation
Preload Dependency by Impedance Cardiography After Cardiac Surgery
The primary purpose of this study is to investigate wether the measure of stroke volume (SV) variations by impedance cardiography during passive leg raising (PLR) can reliably predict preload dependency after cardiac surgery, in…
- Trial name
- NCT02132871
- Testing
- Impedance cardiography Physioflow ®
- Where
- France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Strasbourg, France
Coronary Artery Bypass Grafting, Fluid Therapy
Comparison of Dynamic Fluid Responsiveness by EIT and Transpulmonary Thermodilution in Postoperative of CABG Patients
The purpose of this study is to evaluate the stroke volume variation measured by both methods: transpulmonary thermodilution and electrical impedance tomography (EIT), during fluid responsiveness maneuvers and after fluid…
- Conditions
- Coronary Artery Bypass Grafting, Fluid Therapy, Stroke Volume, Hemodynamic Monitoring
- Trial name
- NCT04362033
- Testing
- Passive Leg Raising (PLR) and PEEP increment (PEEP)
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Ludhmila Abrahão Hajjar
Critical Illness
Hemodynamic Variations During Remote Ischemic Conditioning in Critical Ill Patients
The main objectives of this study are to evaluate the changes in hemodynamics occurring during the remote ischemic conditioning (RIC) procedure and to compare the hemodynamic responses elicited by passive leg raising before and…
- Trial name
- HERICA (NCT06536231)
- Testing
- Remote ischemic conditioning
- Where
- Lithuania
- Volunteers
- 50 people
- Sponsor
- Lithuanian University of Health Sciences