Clinical trials: Parturients
Parturients
Epidural Sonoanatomy Between Parturient and Non-Pregnant
The failure in indwelling epidural catheter for a parturient might cause an anesthetic difficulty. Furthermore, no one can predict the accuracy of needle placement prior to skin puncture with any of landmark-based technique.
- Trial name
- NCT00811707
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Postpartum Hemorrhage
Carbetocin Versus Ergometrin in the Prevention of Postpartum Hemorrhage
In the present study will be compared Carbetocin with ergometrin in the prevention of postpartum haemorrhage (PPH) in parturients that are undergoing caesarean section and are not presenting risk factors for PPH.
- Trial name
- NCT04300452
- Testing
- Carbetocin, Ergometrine Maleate
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Pregnancy Preterm, Neonatal Hypoglycemia
Continuous Glucose Monitoring of Late Preterm Birth After Corticosteroids
Women undergoing late preterm birth are at high risk of delivering a newborn with neonatal hypoglycemia. The investigators plan to monitor interstitial glucose levels prior to delivery in these women in order to develop a better…
- Conditions
- Pregnancy Preterm, Neonatal Hypoglycemia, Prematurity
- Trial name
- NCT03738293
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Placenta Previa, Placenta Accreta
ROTEM in Patients With Placenta Previa
The rotational thromboelastogram (ROTEM) test can be performed on patients with placenta previa/accreta/increta/percreta who have a high likelihood of massive bleeding, and the predictors can be identified by comparing the…
- Conditions
- Placenta Previa, Placenta Accreta, Placenta Increta, Placenta Percreta
- Trial name
- NCT04213755
- Testing
- ROTEM
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Elective Cesarean Section, Preeclampsia
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg…
- Trial name
- NCT04370847
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Adverse Effect
Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the suitable infusion dose of phenylephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04576663
- Testing
- Normal saline, Phenylephrine
- Volunteers
- 95 people
- Sponsor
- General Hospital of Ningxia Medical University
Pregnancy, Respiratory Aspiration of Gastric Content
Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery
The presence of solid food or fluid residue in the stomach is always a major concern when patients require medical procedures under sedation or general anesthesia, due to the high risk of pulmonary aspiration of the stomach…
- Trial name
- NCT05946447
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Parturients, Elective Cesarean Delivery
Maternal Satisfaction After Spinal Anesthesia for Cesarean Delivery
The goal of this observational study is to evaluate the impact of four different spinal anesthesia regimens on maternal satisfaction following cesarean delivery.
- Trial name
- NCT07438171
- Testing
- Bupivacaine %0.5 (hyperbaric), Bupivacaine %0.5 (hyperbaric) and morphine, Bupivacaine %0.5 (hyperbaric), morphine and fentanyl 15
- Volunteers
- 200 people
- Sponsor
- University of Novi Sad
Hypotension
Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients
The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section
- Trial name
- THSAP (NCT01930227)
- Testing
- TEAS, Non-acupoint stimulation
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- wangqiang
Obesity, Morbid, Spinal Anesthesia
ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
The aim of this study is to determine the ED90 of hyperbaric intrathecal bupivacaine for the super obese population undergoing cesarean section under a combined spinal epidural technique.
- Conditions
- Obesity, Morbid, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT03781388
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Duke University
Labor Pain
Epidural Placement Using Handheld Ultrasound Device vs. Traditional Landmark Palpation
Ultrasound is widely in uses for vascular, nerve block and sometimes neuraxial block. The purpose of the study is to evaluate the impact of a handheld ultrasound device on the time to complete labor epidural placement and success…
- Trial name
- NCT04020042
- Testing
- Ultrasound image guidance, Landmark palpation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Texas Southwestern Medical Center
Post-Dural Puncture Headache
Long Term Outcomes Following a Post Dural Puncture Headache
Epidural analgesia is considered a gold standard method for treatment of labor pain. One of the major risks with epidural analgesia is an accidental dural puncture, which leads to a post dural puncture headache.
- Trial name
- NCT03550586
- Testing
- Questionaires
- Where
- 2 sites in Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Pain Score (VAS)
Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia
Post-dural puncture headache (PDPH) is a well-recognized and potentially serious complication of subarachnoid block. While advancements in spinal needle design have reduced its incidence in recent years, PDPH still affects a…
- Trial name
- NCT06607861
- Testing
- saline group, dexmedetomidine group, lidocaine group
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Minia University
Hypotension During Surgery
Electrical Acupoint Stimulation Reduces Intrathecal Anesthesia Induced Hypotension
The parturients may suffer from hypotension after spinal anesthesia and the incidence could be as high as 70-80% when pharmacological prophylaxis is not used.
- Trial name
- EARTH (NCT05724095)
- Testing
- high frequency acupoint stimulation, low frequency acupoint stimulation, electrodes attached
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhihong LU
Obesity, Pregnancy
Inflammation in Obese Parturients: Surgical Outcomes After Elective Caesarean Section
Hypothesis: The investigators propose that obese parturients will have an increased inflammatory response and a decreased anti-inflammatory response to the surgical and anesthetic insult of caesarean section and that this will be…
- Conditions
- Obesity, Pregnancy, Cesarean Section
- Trial name
- NCT01836315
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Manitoba
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Epidural; Anesthesia
Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients
Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space…
- Trial name
- NCT04352283
- Testing
- Preprocedural ultrasound exam of lumbar spine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Caen
Postpartum Haemorrhage
Topical Tranexamic Acid in Caesarean Section
The objective of this study is to investigate whether topical application of tranexamic acid into the uterine cavity and the surgical site intra-operatively can reduce blood loss and provide better surgical haemostasis in…
- Trial name
- TXACS (NCT02492087)
- Testing
- Topical tranexamic acid, Normal saline 0.9%
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- Dr Meng-Li Lee
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against post-spinal anesthesia hypotension.
- Trial name
- NCT04272567
- Testing
- Norepinephrine, Normal saline
- Where
- China
- Volunteers
- 99 people
- Sponsor
- General Hospital of Ningxia Medical University
Anesthesia, Obstetrical
The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia
Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined…
- Trial name
- NCT03164096
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University