Clinical trials: Parodontitis
Periodontitis
Effect of Menstrual Cycle Phase on Pain Perception and Anxiety During Non-Surgical Periodontal Treatment
This study evaluates the effect of menstrual cycle phases on pain perception and dental anxiety during non-surgical periodontal therapy in premenopausal women with Stage II and III periodontitis.
- Trial name
- MAPP (NCT07719686)
- Testing
- Non Surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Karadeniz Technical University
Periodontitis
Hyaluronan in the Treatment of Residual Pockets in Periodontitis Patients.
Aim To evaluate the clinical and microbiological effects of a hyaluronan (HY) as adjunct to scaling and root planning of residual pockets during supportive periodontal therapy.
- Trial name
- NCT04792541
- Testing
- HY containing gel; GUM® Afta Clear Gel, Sunstar, saline solution
- Volunteers
- 66 people
- Sponsor
- Malmö University
Periodontitis, Adult
Evaluation of Multiple Subgingival Irrigations.
The study will be conducted at the Department of Periodontology, Cliniques universitaires Saint Luc. Patients diagnosed with Generalized Chronic Periodontitis (GChP) based on the current classification of the American Academy of…
- Trial name
- POLYVIDONE (NCT03432975)
- Testing
- Povidone-Iodine 10%, Saline Solution
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Rheumatoid Arthritis
Effect of Controlling Environmental Risk Factors in Established RA
The factors contributing to the development of rheumatoid arthritis are multiple, with a role of the environment and a predisposing genetic background.
- Trial name
- DISRUPT-estRA (NCT05198271)
- Testing
- Management of risk factors, Smoking cessation, weightloss
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Chronic Periodontal Disease
Effect of Baduanjin Exercise on Chronic Periodontal Disease in Elderly
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus.
- Trial name
- NCT05484479
- Testing
- Baduanjin training/exercise
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Periodontitis, Intrabony Periodontal Defect
Clinical Evaluation of Nano-Hydroxyapatite as an Adjunctive to Minimally Invasive Non-Surgical Technique in the Treatment of Deep Intra-bony Defects
This randomized controlled clinical trial aims to evaluate the effectiveness of using nano-hydroxyapatite (nHA) gel alongside a minimally invasive non-surgical technique (MINST) to treat deep intra-bony defects in patients with…
- Trial name
- MINST (NCT07608783)
- Testing
- Minimally invasive non-surgical technique (MINST), nano-hydroxyapatite
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Periodontitis, Coronariopathy
Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles in Patients With Coronariopathies
Objective: The aim of this study was to examine the effects of non-surgical periodontal treatment on the hemogram, glycemic and lipid profiles in cardiopathic patients with an indication for surgical revascularization.
- Trial name
- NCT02150005
- Testing
- Periodontal treatment
- Volunteers
- 22 people
- Sponsor
- Universidade Veiga de Almeida
Periodontitis, Periodontal Diseases
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic…
- Trial name
- NCT00066066
- Testing
- Scaling and root planing, Metronidazole, Amoxicillin
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- The Forsyth Institute
Periodontal Diseases, Periodontal Inflammation
Minimally Non Surgical Periodontal Therapy Compared to Traditional Approach
This study aims to evaluate the clinical results of non-surgical periodontal therapy performed with micro-instruments compared to traditional approach (standard curettes) after 6 months of follow-up.
- Trial name
- NCT05060601
- Testing
- Gracey micro-curettes, Standard Gracey curettes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Obesity, Periodontitis
The Relationship Between Body Mass Index and Periodontitis
This study aimed to examine the relationship between body mass index (BMI) and stage/grade of periodontitis per the current classification of periodontal diseases. 142 patients (82 males/60 females) were included in this study.
- Trial name
- NCT04743336
- Testing
- Measuring pocket depth
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Baskent University
Periodontal Disease
Omega-3 and Aspirin in Periodontal Regeneration
To evaluate the efficacy of systemic administration of omega 3 PUFA plus low dose aspirin as an adjunctive therapy to regenerative modality of grade II furcation defects in periodontitis patients.
- Trial name
- PR (NCT01113528)
- Testing
- Regenerative therapy (omega 3 PUFA plus low dose aspirin), Sugar pill
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Periodontitis, Gingivitis
Intraoral Scanners as a Motivation Method for Oral Hygiene Instruction
Periodontal diseases are highly prevalent inflammatory diseases. These diseases are mostly due to the development and the maturation of bacterial plaque which lead to local inflammation.
- Trial name
- Perio3D (NCT05079204)
- Testing
- Intra oral scan, No intervention
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Periodontal Diseases, Periodontitis
Staging and Grading of Periodontitis: Five Years Later
The goal of this observational study is to investigate the ability of Periodontists, Clinicians with Expertise in Periodontics and General Dental Practitioners to diagnose periodontitis using the 2017 AAP / EFP World Workshop…
- Trial name
- NCT06188884
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Mental Health Issue, Periodontitis
Association Between Periodontal Status and Mental Health in Postpartum Women
Background- In developing countries like India, seeking mental health care is still a taboo, and a lot of stigma is attached to consulting a psychiatric specialist or a counselor.
- Conditions
- Mental Health Issue, Periodontitis, Periodontal Diseases
- Trial name
- NCT05869981
- Where
- India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Diabetes Mellitus, Type 2, Apical Periodontitis
Association of Apical Periodontitis With Systemic Level of Inflammatory Markers : A Longitudinal Intervention Study
While cross-sectional studies have reported a significant association between diabetes and Apical Periodontics, prospective studies are scarce.
- Trial name
- NCT05814965
- Testing
- endodontic treatment in the form of root canal treatment, endodontic treatment, assessment of inflammatory marker
- Where
- India
- Volunteers
- 280 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Sterify Gel as an Adjunct to Non-Surgical Periodontal Therapy in Periodontitis
This retrospective observational study will evaluate the clinical response to Sterify Gel, a sterile mucoadhesive polymeric hydrogel, when used as an adjunct to non-surgical periodontal therapy in adult patients with stage II…
- Trial name
- Sterify (NCT07672665)
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele
Periodontal Diseases
Effect of Intracanal Medicaments on Post-Operative Pain in Symptomatic Apical Periodontitis: An RCT
Comparison of different intracanal medicaments during root canal treatment to assess their effect on post-operative pain in teeth with Symptomatic Apical Periodontitis
- Trial name
- NCT07123792
- Testing
- Calcium Hydroxide (20%), Chlorhexidine Gel (2%), Modified Triple Antibiotic Paste
- Where
- Pakistan
- Volunteers
- 480 people
- Sponsor
- HITEC-Institute of Medical Sciences
Periodontitis, Rheumatoid Arthritis
The Effect of Non-Surgical Periodontal Therapy on Rheumatoid Arthritis
Periodontitis is a common chronic inflammatory disease characterised by the destruction of the soft and hard tissues supporting the tooth, including alveolar bone, periodontal ligament and cementum.
- Trial name
- NCT06245265
- Testing
- ELISA (Enzyme-Linked ImmunoSorbent Assay)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biruni University
Apical Periodontitis
Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Study aimed at assessing the clinical and radiographic success of pulp regeneration using injectable platelet-rich fibrin in mature permanent molars with apical periodontitis versus root canal treatment using Gutta Percha (GP)…
- Trial name
- NCT06086249
- Testing
- Regeneration using Injectable platelet-rich fibrin, Root canal treatment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis Complex
Antibiotic and Probiotic Therapies in the Adjuvant Treatment of the Chronic Periodontitis.
Currently, with the increase of bacterial resistance to antibiotics associated with its side effects, it is necessary to find other adjuncts to combat the disease that are an alternative to the use of antibiotics.
- Trial name
- NCT03692819
- Testing
- Amoxicillin 500 Mg, Lactobacillus reuteri Oral Drops
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho