Chronic Periodontal DiseaseNCT05484479
Effect of Baduanjin Exercise on Chronic Periodontal Disease in Elderly
A study testing Baduanjin training/exercise in people with Chronic Periodontal Disease, run by Cairo University at 1 site in Egypt.
Trial summary
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low levels of high-density lipoprotein) and hypertension. Read more about this study
- Who is it for?
- Ages 65 to 75 years
- Conditions the study is for
- Chronic Periodontal Disease
- What is being tested?
- Baduanjin training/exercise
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Oct 2022to 1 May 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 75 years
- All sexes
- No healthy volunteers
- Older adult
Who may be able to join
- fifty elderly with metabolic syndrome and chronic periodontal disease will be included
- both sexes will be included
Who cannot join
- smokers
- elderly engaged in physical activity programs
- any cardiovascular/respiratory diseases that obstacle the conduction of Baduanjin
- elderly on drug therapies for chronic periodontal disease
Trial locations and contacts
1 site in 1 country.
Egypt1 site, 1 recruiting
- Recruiting
Faculty of Physical Therapy Cairo University
Giza, Dokki
Ali Ismail, lecturer, 02 01005154209, allooka2012@gmail.com
About this study
Official title: Baduanjin-exercise Efficacy on Chronic Periodontal Disease in Elderly
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low levels of high-density lipoprotein) and hypertension. An association of periodontal disease and MetS has been suggested. This association is believed to be the result of systemic oxidative stress and an exuberant inflammatory response.
Physical activity is associated as a potential tool for reduction of periodontal disease prevalence. The frequency of physical activity is directly related to a low occurrence of periodontitis.
Read the detailed description
For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be involved in sixty-minute Baduanjin physical training (5 session weekly). Also, for 6 months, another MeTS elderly (25 elderly) with chronic periodontal disease will serve as a control non-trained group.
- Conditions
- Chronic Periodontal Disease
- Being tested
- Baduanjin training/exercise
- Medical subject headings
- Chronic Periodontitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Baduanjin training/exerciseBehavioural
For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be trained using sixty-minute Baduanjin training/exercise (5 times weekly)
| Study group | Role | What they receive |
|---|---|---|
| Exercised group | Experimental | For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be trained using sixty-minute Baduanjin training/exercise (5 times weekly) Receives: Behavioral: Baduanjin training/exercise |
| control group | No intervention | For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will receive no training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Periodontal disease index
it will assess periodontal health status
Measured: It will be assessed after 6-month intervention
Secondary outcomes (5)
Simplified oral hygiene index
it will assess oral hygiene/cleanliness status
Measured: It will be assessed after 6-month intervention
Interleukin 1 beta
it will be assessed in saliva
Measured: It will be after 6-month intervention
interleukin 6
it will be assessed in saliva
Measured: It will be assessed after 6-month intervention
superoxide dismutase
it will be assessed in saliva
Measured: It will be assessed after 6-month intervention
total antioxidant status
it will be assessed in saliva
Measured: It will be assessed after 6-month intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Aug 2022
- Study start1 Oct 2022
- Primary completion1 May 2023 (estimated)
- Study completion1 May 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Chronic Periodontal DiseaseStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ali Mohamed Ali ismail, Cairo University
- Investigators
- Ali Ismail, lecturer, Principal investigator, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05484479
- Sponsor's protocol ID
- P.T.REC/012/003757
- Status last verified
- Dec 2022
- First submitted
- 30 Jul 2022
- Last updated
- 23 Dec 2022
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Ali Ismail AM, El-Moatasem AM, El-Moatasem AM. Effect of baduanjin exercise on salivary inflammatory and oxidative markers in the elderly with metabolic syndrome and periodontal disease: a randomized trial. J Bodyw Mov Ther. 2025 Dec;45:536-544. doi: 10.1016/j.jbmt.2025.09.017. Epub 2025 Sep 16.
PubMed 41316618
Study at a glance
From the registry record, last updated by the sponsor on 23 Dec 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Baduanjin-exercise Efficacy on Chronic Periodontal Disease in Elderly
- ClinicalTrials.gov ID
- NCT05484479
- Acronym / sponsor ID
- P.T.REC/012/003757
- Conditions
- Chronic Periodontal Disease
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Oct 2022 (actual)
- Primary completion
- 1 May 2023 (estimated)
- Study completion
- 1 May 2023 (estimated)
- First posted
- 2 Aug 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low levels of high-density lipoprotein) and hypertension. An association of periodontal disease and MetS has been suggested. This association is believed to be the result of systemic oxidative stress and an exuberant inflammatory response.
Physical activity is associated as a potential tool for reduction of periodontal disease prevalence. The frequency of physical activity is directly related to a low occurrence of periodontitis.
Detailed description
For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be involved in sixty-minute Baduanjin physical training (5 session weekly). Also, for 6 months, another MeTS elderly (25 elderly) with chronic periodontal disease will serve as a control non-trained group.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Exercised group | Experimental | Behavioral: Baduanjin training/exerciseFor 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be trained using sixty-minute Baduanjin training/exercise (5 times weekly) |
| control group | No intervention | –For 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will receive no training |
Who may qualify
- Ages
- 65 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (2 listed)
- fifty elderly with metabolic syndrome and chronic periodontal disease will be included
- both sexes will be included
Key exclusion criteria (4 listed)
- smokers
- elderly engaged in physical activity programs
- any cardiovascular/respiratory diseases that obstacle the conduction of Baduanjin
- elderly on drug therapies for chronic periodontal disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Baduanjin training/exerciseFor 6 months, MeTS elderly (25 elderly) with chronic periodontal disease will be trained using sixty-minute Baduanjin training/exercise (5 times weekly) | Behavioural | Exercised group |
Primary outcome
Periodontal disease index
Time frame: It will be assessed after 6-month intervention
it will assess periodontal health status
5 secondary outcomes
Simplified oral hygiene index
Time frame: It will be assessed after 6-month intervention
Interleukin 1 beta
Time frame: It will be after 6-month intervention
interleukin 6
Time frame: It will be assessed after 6-month intervention
superoxide dismutase
Time frame: It will be assessed after 6-month intervention
total antioxidant status
Time frame: It will be assessed after 6-month intervention
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Dec 2022.
- Derived from this study: PubMed 41316618Ali Ismail AM, El-Moatasem AM, El-Moatasem AM. Effect of baduanjin exercise on salivary inflammatory and oxidative markers in the elderly with metabolic syndrome and periodontal disease: a randomized trial. J Bodyw Mov Ther. 2025 Dec;45:536-544. doi: 10.1016/j.jbmt.2025.09.017. Epub 2025 Sep 16.
Related trials for Chronic Periodontal Disease
RecruitingObservational study
Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years
Diabete Mellitus, Dyslipidaemia
RecruitingObservational study
Evaluation of Masticatory Performance in Patients With Periodontitis
Periodontitis, Adult, Periodontitis
Recruiting
Postoperative Pain and Success of Single-Visit Root Canal Treatment Using Different Root Canal Sealers in Asymptomatic Teeth
Single-visit, Periapical Periodontitis
Not yet recruitingObservational study
Evaluation of Changes in Oral Health-related Quality of Life During the Treatment of Periodontitis.
Periodontitis, Adult, Periodontitis
Active, not recruitingObservational study
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Peri Implant Mucositis, Peri Implant Bone Loss
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ali Ismail, lecturer principal investigator
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Baduanjin training/exercise in people with Chronic Periodontal Disease, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 23 Dec 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Ali Ismail, lecturer (02 01005154209, allooka2012@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Periodontal disease index (time frame: It will be assessed after 6-month intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05484479, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Dec 2022.