Clinical trials: Parenteral Nutrition
Pneumonia, Pneumocystis Carinii, HIV Infections
Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine Therapy
To compare the use of pentamidine aerosol (inhaled mist) with the standard intravenous method of administration in patients with AIDS related Pneumocystis carinii pneumonia (PCP), to measure the amount of pentamidine aerosol that…
- Trial name
- NCT00000722
- Testing
- Pentamidine isethionate
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Early Intervention in Cognitive Aging
Nutritional intervention in overweight middle aged individuals with subjective memory complaints.
- Trial name
- NCT02751866
- Testing
- Berry fruit powder OR nutritional ketosis
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Cincinnati
Very Low Birth Weight Preterms
Effects of Recto-colic Enemas of Butyrate on the Digestive Disorders of Very Low Birth Weight Preterms <1250 Grams
Clinical management of very low birth weight newborns (VLBW <1250g) consists in several challenges to adapt immature physiological systems to extrauterine life.
- Trial name
- NEOTRANS (NCT01536483)
- Testing
- Butyrate enemas
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Nantes University Hospital
Liver Disease
Preventive and Reversional Effect of Vitamin D on Parenteral Nutrition Associated Liver Disease
Patients who accept long-term parenteral nutrition tend to suffer from liver injury. The mechanism for this injury has two possible explanations. The first possible reason is intrinsic toxic effects of parenteral nutrition.
- Trial name
- NCT02452177
- Testing
- Vitamin D
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shengxian Fan
Intestinal Failure With a Temporary High-output Double Enterostomy
Impact of Chyme Reinfusion Compared to Parenteral Nutrition on the Incidence of Complications in Patients With a Temporary High-output Double Enterostomy: a Multicentre Randomized Controlled Trial - FRY: efFiciency of Reinfusion of chYme - (FRY)
In the case of intestinal failure with a high-output double enterostomy, the parenteral nutrition (PN) is the gold standard treatment until the surgical reestablishment of digestive continuity.
- Trial name
- FRY (NCT02792543)
- Testing
- Entéromate™, parenteral nutrition
- Where
- France
- Volunteers
- 268 people
- Sponsor
- Hospices Civils de Lyon
Cholestasis
Compassionate Use of Omegaven to Reverse Parenteral Nutrition Induced Cholestasis
The purpose of this research study is to see if giving Omegaven (an intravenous fat emulsion containing fish oil) instead of the current lipid emulsion, which contains fat derived from soybeans, as part of your child's…
- Trial name
- NCT01173159
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Advanced Cancer
Caregiver Assessments of the Quality of Home Hospice Care
The Objectives are to administer the Family Evaluation of Hospice Care (FEHC) questionnaire and The Texas Revised Inventory of Grief (TRIG) to caregivers previously enrolled into the parent grant and conduct supplemental analyses…
- Trial name
- NCT00895024
- Testing
- Phone Interview/Questionnaire
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Obesity and Other Hyperalimentation
Digestion of Foods Consumed in Africa
As populations become urbanized in Africa, the change to a more Westernized diet has been associated with rise in obesity and related metabolic syndrome diseases.
- Trial name
- NCT03007368
- Testing
- Rice, Potato, Pasta
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Intestinal Diseases
Influence of Fish Oil Based Intravenous Fat Emulsions on the Epidermal Barrier Function
The epidermal barrier efficacy is determined by the physicochemical properties of the epidermal lipid matrix, among which ω-6 essential fatty acids (EFAs) play a key role. Inversely, the ω-3 EFAs are not found in the epidermis.
- Trial name
- Tewlip (NCT02550860)
- Testing
- soybean oil (SO)-based IVFE (Medialipide), fish oil (FO)-containing IVFE (Lipidem)
- Where
- 2 sites in France
- Volunteers
- 13 people
- Sponsor
- Hospices Civils de Lyon
Crohn Disease
Immune Modulation by Parenteral Fish Oil in Patients With Crohn's Disease
To evaluate the effects of infusion of a Fish oil-based lipid emulsion on TNF-α production and other relevant immune functions. A soybean oil emulsion, rich in the omega-6 polyunsaturated fatty acid linoleic acid, will serve as…
- Trial name
- NCT02349594
- Testing
- Omegaven 10%, Intralipid 20%
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Radboud University Medical Center
Cholestasis, Parenteral Nutrition
Cholestasis Prevention: Efficacy of IV Fish Oil
Parenteral nutrition (PN) solutions are life saving in patients with surgical gastrointestinal diseases. However, the use of PN in pediatric populations, especially premature infants, is frequently associated with liver injury…
- Trial name
- NCT00512629
- Testing
- Omegaven, Intralipid
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Implementation of OPAT in Germany
Outpatient Parenteral Antibiotic Therapy in the Metropolitan Area of Cologne
Many infectious diseases require a therapy that is administered intravenously due to a lack of oral treatments. Affected patients often have to stay weeks or even months in hospital just for receiving their therapy although they…
- Trial name
- NCT04002453
- Testing
- Outpatient Parenteral Antibiotic Therapy
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Cologne
Systemic Inflammatory Response Syndrome
Safety and Efficacy of Adding Intravenous N-acetyl Cysteine in Colon Surgeries
The use of antioxidant agents in the prevention or decreasing the severity of postoperative systemic inflammatory response syndrome after colonic surgeries adopted nowadays.
- Trial name
- NCT03589495
- Testing
- N Acetyl L Cysteine, dextrose 5%
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole
Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia
Randomized phase III trial to compare the effectiveness of methotrexate with that of dactinomycin in treating patients who have gestational trophoblastic neoplasia.
- Conditions
- Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole, Non-Metastatic Gestational Trophoblastic Tumor, Uterine Corpus Choriocarcinoma
- Trial name
- NCT00003702
- Testing
- Dactinomycin, Methotrexate
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Gynecologic Oncology Group
Pain, Postoperative
Efficacy and Safety of IV Diclofenac (DIC075V) for Pain After Abdominal or Pelvic Surgery
This study will compare repeated intermittent IV dosing of diclofenac in patients with moderate to severe post-surgical pain from abdominal or pelvic surgery.
- Trial name
- NCT00448110
- Testing
- Intravenous Diclofenac (DIC075V), Intravenous Ketorolac
- Where
- 14 sites in United States
- Volunteers
- 331 people
- Sponsor
- Javelin Pharmaceuticals
Critical Illness
The Energy Dose Study
The investigators have designed this single-center Randomized Clinical Trial (RCT) to prospectively compare, for the first time, the clinical efficacy of different energy doses in intensive care unit (ICU) patients requiring…
- Trial name
- NCT01369147
- Testing
- Parenteral Nutrition, Propofol, Clevidipine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Emory University
Pulmonary Arterial Hypertension
Study of Cicletanine for Pulmonary Arterial Hypertension (PAH)
This Phase 2, randomized, double-blind, placebo-controlled, multicenter, dose-ranging study will compare the efficacy, safety, and tolerability of cicletanine hydrochloride (HCl) to placebo in subjects with PAH.
- Trial name
- NCT00832507
- Testing
- Cicletanine
- Where
- 56 sites in United States, Australia and 8 more
- Volunteers
- 162 people
- Sponsor
- Gilead Sciences
Critical Illness
Parenteral Nutrition With Intravenous and Oral Fish Oil for Intensive Care Patients
The primary objective is to assess the effect of fish oil-enriched enteral and parenteral nutrition on blood oxygenation in critically ill patients.
- Trial name
- NCT01162928
- Testing
- Nutriflex Omega special + Oxepa, Nutriflex Lipid special + Pulmocare
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- B. Braun Melsungen AG
Catheter-related Bloodstream Infection (CRBSI) Nos
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
The purpose of the investigation is to compare two catheter lock solutions (TaurolockTMHep100 and Heparin 100 IE/ml), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a central…
- Trial name
- NCT01948245
- Testing
- TaurolockTMHep100, Heparin 100 IE/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Palle Bekker Jeppesen
Liver Failure, Critical Illness
Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure
The purpose of the study is to determine the tolerance on lipid metabolism and the safety of short-term parenteral nutrition as compared to enteral nutrition in critically ill patients with liver failure.
- Trial name
- SELLIFA (NCT00522730)
- Testing
- Parenteral nutrition, Enteral nutrition
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain