Clinical trials: Paraplegia, Spinal
Spinal Cord Injury, Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI (WINY)
This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT07222033
- Testing
- Hands-free exoskeleton
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Spinal Cord Injury, Paraplegia
Exoskeletal-assisted Walking to Improve Mobility, Bowel Function and Cardio-Metabolic Profiles in Persons With SCI
The primary objective of this study is to achieve successful walking skills using exoskeletal walking devices over the course of 36 sessions in 3 months at specific velocities and distances in people with chronic SCI who are…
- Conditions
- Spinal Cord Injury, Paraplegia, Tetraplegia
- Trial name
- EAWSCI (NCT02314221)
- Testing
- Exoskeletal-assisted walking (ReWalk, Ekso)
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries, Shoulder Impingement Syndrome
Freehand Ultrasound to Evaluate Scapular Kinematics in People With Paraplegia
Shoulder pain is very common in people with spinal cord injury (SCI). Persons with high-level paraplegia have higher chances to suffer shoulder pain and injury than those with lower-level paraplegia due to the shoulder muscle…
- Trial name
- FUS (NCT02357914)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Extracorporeal Shockwave Therapy (ESWT) to Improve Function in Chronic ASIA-A Patients
The global prevalence of spinal cord injury is estimated between 236 to 4187/Million. A spontaneous recovery of the sense-motoric function is decreasing with the time after injury and is only seen sporadically after 1 to 2 years.
- Trial name
- NCT03399968
- Testing
- ESWT
- Where
- 2 sites in Austria
- Volunteers
- 25 people
- Sponsor
- AUVA Trauma Center Meidling
Spinal Cord Injuries
Resistance Training to Improve Strength and Functional Trunk Stability in Adults With Paraplegia
The purpose of this study is to examine the effectiveness of an 8- week resistance training routine to improve functional trunk strength, muscle activation, and physical functioning in exercise in 30 adults with paraplegic SCI.
- Trial name
- NCT03949699
- Testing
- Resistance training
- Volunteers
- 11 people
- Sponsor
- Spaulding Rehabilitation Hospital
Myelitis, Transverse, Flaccid Paraplegia, Complete, Acute
Collaborative Assessment of Pediatric Transverse Myelitis: Understand, Reveal, Educate or CAPTURE Study
Patients and families are invited to participate in an online registry and data repository specifically for patients with transverse myelitis (TM) or acute flaccid myelitis (AFM).
- Conditions
- Myelitis, Transverse, Flaccid Paraplegia, Complete, Acute, Flaccid Paraplegia, Incomplete, Acute
- Trial name
- TMCAPTURE (NCT02144935)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Texas Southwestern Medical Center
Spinal Cord Injuries, Quadriplegia
Retraining Walking After Spinal Cord Injury
Incomplete spinal cord injury often results in difficulty walking. Training on a treadmill with body weight support may improve walking ability after spinal cord injury.
- Conditions
- Spinal Cord Injuries, Quadriplegia, Paraplegia, Central Cord Syndrome
- Trial name
- NCT00059553
- Testing
- Locomotor treadmill training with body weight support
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Flaccid Hemiplegia, Flaccid Paraplegia
European Paediatric AFM Associated With EV-D68 Follow-up Study.
The study is a follow-up study on children with acute flaccid paresis associated with enterovirus D68 infection. Only children living in Europe are eligible.
- Conditions
- Flaccid Hemiplegia, Flaccid Paraplegia, Flaccid Tetraplegia, Unspecified, Enterovirus D68
- Trial name
- NCT03499366
- Testing
- HFMS, MRC, ACTIVLIM, PedsQl-4.0
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Neuromuscular Diseases, Obesity (Disorder)
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
The ActiLiège-Adult study is a prospective, longitudinal, observational study designed to collect natural history data on adult patients with neurological or metabolic diseases affecting movement.
- Conditions
- Neuromuscular Diseases, Obesity (Disorder), Myotonic Dystrophy 1, Myasthenic Syndrome
- Trial name
- Acti-Adult (NCT07136844)
- Testing
- Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Motor Neuron Diseases, Spinocerebellar Ataxias
Rare Disease Registry Database for Movement Disorders in Southern Anhui Province
According to the World Health Organization (WHO) definition, a rare disease is a disease affecting fewer than 6.5 people per 10,000; in China, it generally refers to diseases with a prevalence of less than 1/10,000 (i.e., with a…
- Conditions
- Motor Neuron Diseases, Spinocerebellar Ataxias, Hereditary Muscular Dystrophy, Hereditary Spastic Paraplegia
- Trial name
- W-MoSCA (NCT07838883)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Spinal Cord Injuries, Paraplegia
Evaluation of Safety and Performance of the Atalante System With Patients With Lower Limb Paralysis
The study is a prospective, open, bicentric and observational study. It is conducted to assess the safety and performance of the Atalante exoskeleton system with patients with lower limb paralysis.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paralysis, Lower Limbs, Lower Extremity
- Trial name
- NCT04110561
- Testing
- Use of the Atalante exoskeleton
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Wandercraft
Spinal Cord Injuries
Experience of Rehabilitation Amongst Individuals With Paraplegia
This study is a qualitative study exploring the facilitators to physical and vocational rehabilitation and also explores the barriers in empowering individuals with paraplegia
- Trial name
- NCT05267223
- Testing
- Semi-structured interviews
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Asir John Samuel
Spinal Cord Injuries
Hybrid High-intensity Interval Training for Persons With Spinal Cord Injury. A Feasibility Study
This study examines safety and feasibility of a study protocol using a combination of functional electrical legcycling with voluntary armwork (hybrid training) as either skiergometer or armcycling in high intensity intervals for…
- Trial name
- NCT04211311
- Testing
- hybrid high-intensity training
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Southern Denmark
Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy
A Patient Centric Motor Neuron Disease Activities of Daily Living Scale
The purpose of this study is to learn about rates of patient-reported disease progression in patients with motor neuron diseases (amyotrophic lateral sclerosis, progressive muscular atrophy, primary lateral sclerosis, hereditary…
- Conditions
- Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02852278
- Testing
- Web-based Survey
- Volunteers
- 410 people
- Sponsor
- University of South Florida
Spinal Cord Injuries, Spinal Cord Injury Cervical
Developing Strategies to Optimize the Exercise Response After Tetraplegia.
To identify means to improve exercise performance in participants with tetraplegia.
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury Cervical, Paraplegia, Spinal
- Trial name
- NCT04465825
- Testing
- HITT: intermittent high intensity exercise
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Paraplegia, Spinal Cord Injuries
Natural History of Shoulder Pathology in Manual Wheelchair Users
Over 300,000 people in the United States have spinal cord injuries and many use manual wheelchairs for mobility. Most manual wheelchair users will develop shoulder injuries and pain that greatly affect quality of life and level…
- Conditions
- Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
- Trial name
- NHSSI (NCT02600910)
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Spinal Cord Injury
Indego Exoskeleton After SCI
The purpose of this study is to assess the use of Indego as a gait training tool for subjects with complete or incomplete paraplegia as a result of spinal cord injury (SCI) who have preserved lower extremity function.
- Trial name
- NCT02793635
- Testing
- Indego Powered Exoskeleton
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Parker Hannifin Corporation
Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
This study will use a magnetic resonance imaging technique called nuclear magnetic spectroscopy (H-MRS) to define the pathology and progression of primary lateral sclerosis, hereditary spastic paraplegia and amyotrophic lateral…
- Conditions
- Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
- Trial name
- NCT00023075
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Cord Injuries, Spinal Cord Compression
Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment Study
The SciExVR study will evaluate the potential benefit of autologous bone marrow derived stem cells (BMSC) in the treatment of spinal cord injury with evidence of impaired motor or sensory function.
- Conditions
- Spinal Cord Injuries, Spinal Cord Compression, Spinal Cord Ischemia, Spinal Cord Diseases
- Trial name
- SciExVR (NCT03225625)
- Testing
- Paraspinal, Paraspinal EX, Paraspinal VR
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- MD Stem Cells