Clinical trials: Pancreatitis, Chronic
Chronic Pancreatitis
Fat Malabsorption in Chronic Pancreatitis
The objective of this study is to evaluate the malabsorption blood test (MBT), stool coefficient of fat absorption (CFA) and stool bomb calorimetry (BC) methods as potential screening or diagnostic tests for reduced exocrine…
- Trial name
- NCT02849704
- Testing
- Creon36™
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Chronic Pancreatitis
CPB Versus Sham Treatment for Pain Management in Small Duct Chronic Pancreatitis
This study assesses the pain response to Endoscopic Ultrasound (EUS) guided Celiac Plexus Block (CPB) treatment in comparison to EUS without a pain block administered. All participants will receive medications for pain as needed.
- Trial name
- NCT02054910
- Testing
- Celiac Plexus Block
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Alabama at Birmingham
Chronic Pancreatitis
Safety And Efficacy Of Tanezumab In Patients With Chronic Pancreatitis
Tanezumab is effective in reducing the pain associated with chronic pancreatitis.
- Trial name
- NCT01146561
- Testing
- Tanezumab
- Where
- 9 sites in United States
- Volunteers
- 2 people
- Sponsor
- Pfizer
Acute Pancreatitis (AP), Gallstone Pancreatitis
Pentoxifylline Treatment in Acute Pancreatitis (AP)
The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.
- Conditions
- Acute Pancreatitis (AP), Gallstone Pancreatitis, Alcoholic Pancreatitis, Trauma Acute Pancreatitis
- Trial name
- AP (NCT02487225)
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Mayo Clinic
Biliary Stricture
WallFlex Biliary Fully Covered (FC) Chronic Pancreatitis Study
The purpose of this of this study is to compare the use of Self Expanding Metal Stents (SEMS) to plastic stents for the treatment of benign biliary strictures secondary to chronic pancreatitis as it pertains to stricture…
- Trial name
- NCT01543256
- Testing
- WallFlex™ Biliary RX Fully Covered Stent System RMV, Commercially available Plastic Stent Per Investigator preference
- Where
- 14 sites in Australia, Austria and 9 more
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Chronic Pancreatitis
Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis
Primary objective: To describe and compare the safety and efficacy of treatment with AAT in chronic pancreatitis patients who undergo total pancreatectomy and islet autotransplantation (TP-IAT).
- Trial name
- NCT02947087
- Testing
- Prolastin-C
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina
Chronic Pancreatitis, Diabetes Mellitus
Closed Loop Insulin Pump Therapy After Islet Auto-Transplantation
The purpose of this study is to determine the effectiveness of closed loop insulin pump therapy to control blood sugar following total pancreatectomy and islet auto-transplantation (TPIAT).
- Trial name
- NCT01945138
- Testing
- Closed Loop Insulin
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Minnesota
Exocrine Pancreatic Insufficiency, Pancreatic Diseases
Special Investigation of LipaCreon on Long-term Use in Patients With Pancreatic Exocrine Insufficiency
This study aims at collecting the information related to the safety and effectiveness in the pancreatic exocrine insufficiency patients receiving the treatment with LipaCreon for a long term in order to evaluate the effective and…
- Conditions
- Exocrine Pancreatic Insufficiency, Pancreatic Diseases, Digestive System Diseases
- Trial name
- NCT01427725
- Testing
- Lipacreon
- Where
- 189 sites in Japan
- Volunteers
- 579 people
- Sponsor
- Mylan Inc.
Common Bile Duct Stricture
Covered Metallic Stents for First-Line Treatment of Benign Bile Duct Strictures
The current standard of care for benign bile duct strictures involves placement of multiple plastic stents under endoscopic and fluoroscopic guidance to progressively dilate or stretch it open.
- Trial name
- NCT01221311
- Testing
- Fully covered Metallic Stent, Plastic Stent
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 112 people
- Sponsor
- Medical University of South Carolina
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Incorporating Endoscopic Ultrasound and Elastography Towards Improving Outcomes of Pediatric Pancreatitis Management
The main reason for this research study is to find out more about acute recurrent pancreatitis and chronic pancreatitis in children.
- Trial name
- NCT06068426
- Testing
- Transabdominal ultrasound Shear wave elastography
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- David Vitale MD
Chronic Pancreatitis
Efficacy of EUS-guided Celiac Plexus Blockade in Chronic Pancreatitis
This is a triple-blind, parallel group, randomized controlled trial to assess the benefit of triamcinolone injection as a therapeutic measure for control of chronic pancreatitis pain.
- Trial name
- NCT00658736
- Testing
- Triamcinolone, Bupivicaine alone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Chronic Pancreatitis
Viokase 16, Viokase16 Plus Nexium and Nexium Alone
Our primary hypothesis is that the addition of Nexium to Viokase 16 will decrease the chronic abdominal pain in patients with small duct chronic pancreatitis in a superior fashion compared to Viokase 16 plus placebo or to Nexium…
- Trial name
- AZ (NCT01142128)
- Testing
- Nexium (esomeprazole magnesium), Viokase 16 (pancrelipase) + Nexium
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Chronic Pancreatitis
Trial of Indomethacin in Chronic Pancreatitis
The researchers are trying to find a way to slow down the progression of chronic pancreatitis (CP) and investigate the possibility of the long term treatment of this disease.
- Trial name
- NCT04207060
- Testing
- Indomethacin, Endoscopy for Pancreatic Function Testing
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Healthy Volunteers
MRCP: A Reliable, Non Invasive Method for Staging Chronic Pancreatitis in Pediatrics
The goal of this research study is to learn more about the pancreas. The investigators want to use Magnetic Resonance Cholangiopancreatography (MRCP) to learn more about the size of a normal pancreas.
- Trial name
- NCT02869893
- Testing
- Secretin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Pancreatitis, Insulin Resistance
Chronic Pancreatitis. Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life Quality
The purpose of this study is to determine if study drug (Pioglitazone) treatment will improve pre-diabetes (insulin resistance) or ealy diabetes and improve clinical symptoms (pain) or laboratory evidence of chronic pancreatitis.
- Conditions
- Chronic Pancreatitis, Insulin Resistance, Normal or Mildly Abnormal Stool Fat Levels
- Trial name
- NCT00782795
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pancreatitis
Rectal Indomethacin to Prevent Post ESWL-pancreatitis
The purpose of the study is to determine whether rectal indomethacin reduces the incidence of post-ESWL pancreatitis.
- Trial name
- RIPEP (NCT02797067)
- Testing
- indomethacin suppository, Glycerin Suppository
- Where
- China
- Volunteers
- 1,370 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Role of Home-based Transcutaneous Electrical Acustimulation for Treatment of Pain in Patients With Chronic Pancreatitis
This research is studying a new noninvasive device-based therapy called Transcutaneous Electrical Acustimulation (TEA) to learn about its safety and how well it works as a treatment of pain in chronic pancreatitis.
- Trial name
- NCT06015945
- Testing
- Transcutaneous Electrical Acustimulation (TEA)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Type 1
The Effect of Pancreatic Polypeptide on Insulin Requirements for Type 1 & Post-pancreatectomy Diabetic Patients
The goal of this research is to see if pancreatic polypeptide (PP), a hormone that is naturally produced by the pancreas and that works to control the amount of glucose that the liver makes, will reduce the amount of insulin…
- Trial name
- NCT00791076
- Testing
- Pancreatic Polypeptide (PP)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Pancreatitis, Pancreas Divisum
SpHincterotomy for Acute Recurrent Pancreatitis
The purpose of this study is to determine if a procedure called Endoscopic Retrograde CholangioPancreatography (ERCP) with sphincterotomy reduces the risk of pancreatitis or the number of recurrent pancreatitis episodes in…
- Conditions
- Pancreatitis, Pancreas Divisum, Pancreatitis, Acute, Pancreatitis Idiopathic
- Trial name
- SHARP (NCT03609944)
- Testing
- ERCP with miES, EUS
- Where
- 21 sites in United States, Canada
- Volunteers
- 181 people
- Sponsor
- Oregon Health and Science University
Chronic Pancreatitis
WallFlex Pancreatic Metal Stent for Pancreatic Duct Strictures
To prospectively document the performance of a FCSEMS for treatment of pancreatic duct strictures in patients with painful chronic pancreatitis.
- Trial name
- NCT02802020
- Testing
- Pancreatic fully-covered self-expanding metal stent (FCSEMS)
- Where
- 11 sites in United States, Belgium and 4 more
- Volunteers
- 67 people
- Sponsor
- Boston Scientific Corporation