Clinical trials: Palliative Treatment
Cancer
Randomized Controlled Trial of Early Palliative Care for Patients With Advanced Cancer
Patients with advanced cancer often have numerous physical and psychological symptoms, which can negatively affect their quality of life.
- Trial name
- NCT01248624
- Testing
- Early Palliative Care Referral
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- University Health Network, Toronto
Bereaved Families
Incidence and Risk Factors of Prolonged Grief in Palliative Care Units
The purpose of this study is to assess the incidence and risk factors of prolonged grief in family members of patients died in French palliative care units and to explore experience of bereaved families to build a scientifically…
- Trial name
- FAMI-LIFE (NCT03748225)
- Where
- France
- Volunteers
- 609 people
- Sponsor
- Hôpital Franco-Britannique-Fondation Cognacq-Jay
Multiple Sclerosis, Chronic Pain
MS Symptom Management Study
People with Multiple Sclerosis (MS) often have pain and/or fatigue. Unfortunately, available treatments provide inadequate relief for the majority of these individuals.
- Conditions
- Multiple Sclerosis, Chronic Pain, Fatigue
- Trial name
- ENHANCE (NCT02474940)
- Testing
- Intervention #1, Intervention #2, Intervention #3
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Washington
Hemorrhage
Predictive Factors for Major Bleeding Risk in Patients Admitted in a Palliative Care Unit
Even if most patients in palliative care units presented with well-recognized risks factors of venous thromboembolism (VTE) (eg: active cancer, bed rest, previous history of venous thrombosis), the incidence of VTE in palliative…
- Trial name
- RHESO (NCT01056978)
- Where
- 20 sites in France
- Volunteers
- 1,230 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pulmonary Disease, Chronic Obstructive
Morphine for Treatment of Dyspnea in Patients With COPD
Dyspnea is the most reported symptom of patients with advanced Chronic Obstructive Pulmonary Disease (COPD) and is undertreated.
- Trial name
- MORDYC (NCT02429050)
- Testing
- sustained release morphine
- Where
- Netherlands
- Volunteers
- 124 people
- Sponsor
- Maastricht University Medical Center
Ischemic Stroke, Ischaemic Stroke With Coma
Decision Aid Feasibility Trial for Families of Critically Ill Stroke Patients
Severe strokes, including large artery acute ischemic stroke and intracerebral hemorrhage, continue to be the leading cause of death and disability in adults in the U.S.
- Conditions
- Ischemic Stroke, Ischaemic Stroke With Coma, Intracerebral Hemorrhage, Hemorrhagic Stroke
- Trial name
- NCT04143113
- Testing
- Decision Aid
- Where
- 2 sites in United States
- Sponsor
- University of Massachusetts, Worcester
Pediatric Palliative Care, Caregiver Burden
The Effect of Watson Human Care Theory and Acceptance and Commitment Therapy-Based Counseling Program Applied to Parents of Pediatric Palliative Care Patients on Value-Based Life and Care Burden
This study aims to examine the effect of Watson Human Care Theory and Acceptance and Commitment Therapy-based counseling program applied to parents of pediatric palliative care patients on value-oriented living and care burden.
- Conditions
- Pediatric Palliative Care, Caregiver Burden, Acceptance and Commitment Therapy
- Trial name
- NCT07327580
- Testing
- Counseling Program Based on Watson Human Care Theory and Acceptance and Commitment Therapy (ACT)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Frail Elderly Syndrome
Implementing, Evaluating, and Scaling Up of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) Program
This study will evaluate the implementation of the Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) program using a cross-jurisdictional, effectiveness-implementation type II hybrid design (dual testing of clinical…
- Trial name
- NCT03935997
- Testing
- Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) Program
- Where
- 4 sites in Canada
- Volunteers
- 594 people
- Sponsor
- McMaster University
Advanced Cancer
Virtual Dignity Therapy for Palliative Care Patients With Advanced Cancer
The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the Virtual Dignity Therapy intervention to palliative care patients with advanced cancer.
- Trial name
- NCT05113199
- Testing
- Virtual Dignity Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic
Lung Cancer
Mistletoe in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Are Receiving Palliative Chemotherapy
RATIONALE: Mistletoe may help the body build an immune response and may improve quality of life to help patients live more comfortably.
- Trial name
- NCT00052325
- Testing
- mistletoe extract
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Palliative Care
Palliative Care in the ICU
The study compares early palliative care consultation to standard of care in the medical intensive care unit (ICU). The study will assess if the intervention leads to an increased proportion of clearly delineated goals of care…
- Trial name
- NCT03263143
- Testing
- Palliative Care
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Washington University School of Medicine
Leukemia, Multiple Mieloma
The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic Disease
This is a mixed-method, device-free and drug-free multicenter interventional study. The study aims at facilitating end-of-life conversations within the doctor-patient relationship through the use of the Go Wish Game (GWG) and…
- Conditions
- Leukemia, Multiple Mieloma, Advanced Solid Tumors, Lymphoma
- Trial name
- OHGW-ACP (NCT06795815)
- Testing
- Go Wish Game
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Cancer, Cancer Cachexia
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular…
- Conditions
- Cancer, Cancer Cachexia, Inflammation
- Trial name
- PROTECT (NCT04065815)
- Testing
- Resistance Training, WB-EMS, High-intensity interval training (HIIT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Primary Brain Tumor
Impact of the Development of Pediatric Palliative Care
Despite medical advances, cancer remains the leading cause of death by disease in children. Brain tumors are the second most common cause of cancer in children after leukemia, representing 25% of pediatric cancers.
- Trial name
- PTB (NCT05660499)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Non-Small Cell Lung Cancer
Radiation Therapy (XRT) and ZD6474 in Non-Small Cell Lung Cancer (NSCLC)
Primary Objectives: To assess the safety of oral therapy with ZD6474 by evaluating the frequency, severity, and duration of treatment-emergent adverse events in patients with poor prognosis lung cancer.
- Trial name
- NCT00745732
- Testing
- ZD6474 (ZACTIMA), Radiation Therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Malignant Thoracic Neoplasm
Electronic Symptom Monitoring Program for Triggered Palliative Referrals in Patients With Thoracic Cancer
This clinical trial evaluates earlier symptom management through remote electronic symptom monitoring (such as through an app on patient's phone), and accessibility of palliative care self-referral by patients with thoracic…
- Trial name
- NCT06396598
- Testing
- Educational Activity, Electronic Health Record Review, Internet-Based Intervention
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Nutrition Aspect of Cancer, End Stage Cancer
Efficacy of Parenteral Nutrition in Patients at the Palliative Phase of Cancer.
In malnourished patients in the palliative phase of cancer, the question is raised of the relevance of implementing artificial nutritional assistance instead of oral feeding when this is possible.
- Trial name
- ALIM-K (NCT02151214)
- Testing
- Parenteral nutrition
- Where
- 13 sites in France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Palliative Care, Pain
A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy
The purpose of this study is to determine whether Sativex® and GW-2000-02 are effective in the management of subjects with intractable cancer-related pain.
- Conditions
- Palliative Care, Pain, Cancer
- Trial name
- SPRAY (NCT00674609)
- Testing
- Sativex®, THC Alone
- Where
- United Kingdom
- Volunteers
- 177 people
- Sponsor
- Jazz Pharmaceuticals
COPD, Cancer
Patient-centred Integrated Palliative Care Pathways in Advanced Cancer and Chronic Disease
Rationale: Palliative care integration in treatment pathways, palliative care networks and institutional collaborations in health services delivery seems a promising approach reducing fragmentation and discontinuity.
- Conditions
- COPD, Cancer, Heart Failure
- Trial name
- InSup-C (NCT02175147)
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 576 people
- Sponsor
- Radboud University Medical Center
Palliative Care, Chronic Disease
Teaching Parents Reiki for Their Adolescents Receiving Palliative Care
The proposed study addresses National Institute of Nursing Research (NINR) priorities of advancing symptom science to "develop [and] test … novel, scalable symptom management interventions, including complementary health…
- Trial name
- NCT03896165
- Testing
- Reiki
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University