Clinical trials: Palliative Medicine
Palliative Care, Withdrawal of Life Support
End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting
The ARREVE-3 trial will evaluate whether a structured palliative care protocol can improve end-of-life management for mechanically ventilated ICU patients in whom a decision to withdraw life-sustaining therapies has been made.
- Conditions
- Palliative Care, Withdrawal of Life Support, Intensive Care Medicine, Sedation
- Trial name
- ARREVE-3 (NCT07368010)
- Testing
- Protocol for palliative care and life-support withdrawal
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Nantes University Hospital
Pain, Anxiety
Impact of Massage Therapy on the Quality of Life of Hospice Patients
This is a pilot study to evaluate the impact of massage therapy in hospice patients.
- Conditions
- Pain, Anxiety, Depression, Quality of Life
- Trial name
- NCT02880202
- Testing
- Massage Therapy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Mayo Clinic
Patients With Advanced Cancer Receiving Specialized Palliative Care
Empower the Heart of Patients With Terminal Cancer Using Cardiac Medicines Trial
The pathophysiological implications of various cancer diseases and anti-cancer therapies is the occurrence of a cardiac disease-like phenotype with cardiac dysfunction, cardiac wasting, and cardiac homeostasis changes (incl.
- Trial name
- EMPATICC (NCT05636774)
- Testing
- Heart failure medication
- Where
- Germany
- Volunteers
- 97 people
- Sponsor
- University Hospital, Essen
Quality of Life, Stress
Music Therapy Intervention to Reduce Caregiver Distress at the End of Life
This is a study to assess the feasibility and acceptability of implementing a music therapy intervention for caregivers of hospitalized patients who are referred to inpatient hospice.
- Conditions
- Quality of Life, Stress, Anxiety, Depression
- Trial name
- NCT03322228
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Palliative Medicine
The MuSt-PC: a Feasibility Study on Intent to Use a Tool With Regard to Symptom Management
A study on the intent to use a tool (MuSt-PC) to manage symptoms of patients in a palliative care trajectory.
- Trial name
- NCT06110624
- Testing
- Survey
- Where
- 2 sites in Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Cancer, Neoplasms
Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy
New oral anticancer treatments have improved survival across cancer types but introduced challenges in medication adherence and symptom management.
- Trial name
- SMART pilot (NCT07073807)
- Testing
- SMART Intervention using TAPPT® for Adherence, Symptom, Financial, and Social Needs Monitoring
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, Irvine
Terminal Cancer
Nasal Fentanyl and Buccal Midazolam for Dying Patients
When patients are dying they become unable to take oral medication and if they develop symptoms (e.g. pain or agitation) they need to be given a subcutaneous injection of medication.
- Trial name
- NCT02009306
- Testing
- PecFent and Epistatus, Standard subcutaneous medication, Epistatus Alone
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Oral Health Care, Oral Health-Related Quality of Life
Oral Health in Palliative Care: A Survey Study
Oral health problems such as xerostomia or oral infections are common in palliative care patients and can significantly impair quality of life.
- Conditions
- Oral Health Care, Oral Health-Related Quality of Life, Palliative Care, Palliative Care, Patient Care
- Trial name
- OH-PAL (NCT07324525)
- Where
- Germany
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Chronic Illness, Opioid Use
Characteristics and Clinical Implications of a Clinical Decision Support System
The investigators propose to study the feasibility, acceptability, usability and outcomes of a new clinical decision support system for clinicians of opioid therapy in the context of specialist palliative care for serious chronic…
- Conditions
- Chronic Illness, Opioid Use, Palliative Care
- Trial name
- NCT03295097
- Testing
- Clinical Decision Support System
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Hospice of Henderson County, Inc.
Depression in Adolescence
Evaluation of MoodRing on Improving the Quality of Depression Management in Adolescents
The MoodRing intervention is a mobile application for adolescents, parents, and an accompanying web-based clinician portal which enables adolescents to monitor their mood through the use of passively collected smartphone data.
- Trial name
- TECH-E (NCT05376358)
- Testing
- MoodRing App, Usual Care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Ana Radovic
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Anesthesia, Surgery
Veterans Enhanced Recovery Using Integrative Treatments Around Surgery
The study aims to assess the implementation and effectiveness of Integrative Treatments - Music Medicine, Aromatherapy, and Battlefield Acupuncture - in the management of perioperative pain and anxiety, and in the reduction of…
- Conditions
- Anesthesia, Surgery, Knee Arthropathy
- Trial name
- VERITAS (NCT06333938)
- Testing
- Nonpharmacologic Treatment, Standard Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Durham VA Medical Center
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Palliative Medicine
Evaluation of Palliative Care Co-treatment by Attending Physicians and Nurses: an Online Survey as Part of the Project
The subject of the study is an online survey of doctors and nurses who provide (intensive) medical care to patients.
- Trial name
- EPIC-BS (NCT06310889)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Medication Adherence
Technology Enhanced Nurse Navigator Trial (TENN Trial)
The purpose of the Technology Enhanced Nurse Navigator Trial (TENN) Trial is to find the best way to provide breast cancer patients with information through a computer connected to the internet.
- Trial name
- TENN (NCT01596179)
- Testing
- Interactive navigational support, Internet access
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Mercy Medical Center
Palliative Care, Intensive Care Unit
Critical Care and Palliative Care Medicine Together in the ICU
Will earlier palliative care medicine consultation in the ICU result in decreased length of stay in the ICU and hospital, as well as, increased patient and family satisfaction.
- Conditions
- Palliative Care, Intensive Care Unit, Hospice
- Trial name
- NCT03520023
- Testing
- Palliative Care Consult
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Mayo Clinic
Palliative Care, Cancer
Attitudes Towards Deprescribing Medications in Cancer Patients and Impact of Educational Intervention by a Clinical Pharmacist
Participation in this study consists in responding to some questions from two questionnaires in Romanian about how participants feel about deprescribing, participants' treatment and how participants understand medical…
- Trial name
- NCT06771999
- Testing
- Educational intervention by a clinical pharmacist
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Henna, Hand-Foot Syndrome
Effectiveness of the Henna Application in Patients With Hand-Foot Syndrome: Nested Case-Control Study
Introduction: There is an explanation that there is a connection between the application of henna and the occurrence of hand-foot syndrome, and the purpose and progression of this interaction.
- Conditions
- Henna, Hand-Foot Syndrome, Case-Control Study
- Trial name
- [Henna] (NCT06832501)
- Testing
- Henna
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Hacettepe University
Complementary Alternative Medicine, Complementary Alternative Therapy
Use of CAM by Hospice Oncology Patients During Ambulatory Palliative Care
The aim of the study is to assess Prevalence of complementary and alternative therapy use by adult patients from the area of Silesian agglomeration (Poland) with advanced, metastatic cancer disease who were admitted to "Pro…
- Conditions
- Complementary Alternative Medicine, Complementary Alternative Therapy, Hospice Care
- Trial name
- CAM (NCT03747172)
- Testing
- complementary and alternative therapy
- Where
- Poland
- Volunteers
- 1,004 people
- Sponsor
- Silesian University of Medicine
Acute Brain Injury
Safety and Efficacy of Wendan Decoction in Acute Moderated to Severe Brain Injury
Efficacy and safety of Traditional Chinese Medicine (Wendan decoction) combined with conventional neurologic intensive care in patients with acute moderated to severe brain injury in early stage - A randomized controlled study.
- Trial name
- NCT03851809
- Testing
- Wendan decoction combination in acute brain injury
- Volunteers
- 60 people
- Sponsor
- Taichung Tzu Chi Hospital