Clinical trials: Palliative Care, open to volunteers
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Acute Low Back Pain
The Palliative Effect of TENS-WAA on 'Capsaicin/Heat' Induced Acute Lower Back Pain: a Self-controlled Clinical Study
Acute lower back pain is a common condition that occurs in all age groups, and most people will experience acute lower back pain at least once in their lives.
- Trial name
- NCT06944665
- Testing
- Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture theory
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xiaonan Huang
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory
Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma
Patients with multiple myeloma experience a wide range of physical and psychological symptoms from the time of their diagnosis. Meanwhile, patients with aggressive lymphomas undergo unpredictable illness courses, resulting in…
- Conditions
- Multiple Myeloma in Relapse, Multiple Myeloma, Refractory, Multiple Myeloma Stage III, Multiple Myeloma Progression
- Trial name
- EPC-MM+L (NCT06485076)
- Testing
- Early Palliative Care
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Health Literacy, Prostate Cancer
Cancer Literacy Education and Awareness Resources for Prostate Care
The CLEAR-PC project addresses the critical issue of low health literacy in prostate cancer prevention and care, recognising that inadequate health literacy leads to difficulties in understanding complex medical information…
- Trial name
- CLEAR-PC (NCT07437482)
- Testing
- Co-created digital health literacy intervention for prostate cancer prevention and care
- Where
- Spain
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Acute Respiratory Failure, Mechanical Ventilation
A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)
The purpose of this study is to investigate a specific approach to patient care called a time-limited trial (TLT). This approach is sometimes used for people who develop critical illness and are cared for in an intensive care…
- Conditions
- Acute Respiratory Failure, Mechanical Ventilation, Life-Supporting Treatments, Communication
- Trial name
- TIME (NCT06042621)
- Where
- 5 sites in United States
- Volunteers
- 7,818 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Support, Family, The Effects of Educational Intervention on Nurses Performance
Effectiveness of Palliative Care Training and Its Impact on Experiential Learning
Palliative care is a complex concept in nursing that needs special education and training. However, it is not focused and under-recognized discipline and the same is consistent with nursing students.
- Trial name
- NCT07039344
- Testing
- Conventional method of Palliative care Training (Group A), Pedagogical (LWPPR) method of Palliative care Training (Group B)
- Where
- 2 sites in Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Lincoln University College Malaysia
Assisted Dying, Palliative Care
Palliative Care and The Terminally Ill Adults (End of Life) Bill
The current study aims to investigate the potential impact of the proposed Assisted Dying (Terminally Ill Adults (2024) Bill on Palliative care workers.
- Trial name
- NCT07427550
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Cancer, Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative
Is the 1939 Cancer Act Fit for Purpose in the Modern Technology Era?
The 1939 Cancer Act in the UK (England \& Wales) prohibits advertising of cancer treatments to the public, by anyone but the NHS.
- Conditions
- Cancer, Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors), Cancer (With or Without Metastasis)
- Trial name
- NCT07584824
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Oncologic Diseases, Cancer
Implementation and Evaluation of a Program Aimed at Facilitating Palliative Care Conversations
Cancer is one of the leading causes of death worldwide. In the care of people with cancer, it is essential to pay sufficient attention to individual care needs and quality of life.
- Trial name
- MCMV (NCT07402057)
- Testing
- My Care My Voice Intervention
- Where
- 4 sites in Belgium
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Bone Metastases
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
To compare increasing doses and different treatment schedules of stereotactic body radiation therapy (SBRT) against standard treatment scheduling.
- Trial name
- NCT06065449
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pediatric Cancer, Palliative Care
Integration of Palliative Care in Pediatric Onco-hematology
PALONCOPED is a multicentre, interregional, observational and qualitative study aiming to better understand the early integration of palliative care in children with cancer.
- Trial name
- PALONCOPED (NCT07838168)
- Testing
- PALONCOPED semi-structured interview
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Neoplasms
Evaluation and Implementation Preparation of a Proactive Palliative Care Model (ENABLE-SG)
The current interdisciplinary specialist palliative care model focuses on supporting patients with advanced cancer who have complex problems in the last weeks of life.
- Trial name
- ENABLE-SG (NCT06044441)
- Testing
- ENABLE-SG model, Wait-list control
- Where
- Singapore
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Care Giving Burden, Dementia
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for their care recipients with dementia.
- Conditions
- Care Giving Burden, Dementia, Chronic Pain, Pain Management
- Trial name
- PACE-app (NCT07032350)
- Testing
- Web-based pain management support tool, Usual Pain Management Care
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Advanced Cancer, Terminal Malignant Tumors
Nurses' Competence and Role in Survival Prediction and Prognostic Communication
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms.
- Conditions
- Advanced Cancer, Terminal Malignant Tumors, Hospices
- Trial name
- NCT06962553
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pediatric Palliative Care, Caregiver Burden
The Effect of Watson Human Care Theory and Acceptance and Commitment Therapy-Based Counseling Program Applied to Parents of Pediatric Palliative Care Patients on Value-Based Life and Care Burden
This study aims to examine the effect of Watson Human Care Theory and Acceptance and Commitment Therapy-based counseling program applied to parents of pediatric palliative care patients on value-oriented living and care burden.
- Conditions
- Pediatric Palliative Care, Caregiver Burden, Acceptance and Commitment Therapy
- Trial name
- NCT07327580
- Testing
- Counseling Program Based on Watson Human Care Theory and Acceptance and Commitment Therapy (ACT)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Caregiver Burden, Bereavement
Caregiver Stress and Bereavement
The death of a spouse is considered one of the most stressful and impactful life events and is associated with increased morbidity and premature mortality.
- Conditions
- Caregiver Burden, Bereavement, Cancer
- Trial name
- NCT05867706
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease (COPD), Heart Failure
Breathlessness Patterns in Patients With Cancer, COPD and Heart Failure: an fMRI Feasibility Study
Dyspnea that persists despite optimal pathophysiological treatment is defined as persistent dyspnea. Currently all brain functional magnetic resonance imaging (fMRI) studies conducted to evaluate breathlessness have done so using…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Heart Failure, Cancer, Volunteers
- Trial name
- BREACH-fMRI (NCT07319039)
- Testing
- Cerebral fMRI, Immersive virtual reality
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Geriatric, Palliative Care
PALLIATIVE ASSESSMENT COHORT IN THE GERIATRIC EMERGENCY SETTING
The PALMA project is part of a larger palliative research program COPAL in Capital Region of Denmark led by Professor Tom Møller.
- Conditions
- Geriatric, Palliative Care, Socio-demographic Risk, Frailty at Older Adults
- Trial name
- PALMA cohort (NCT06911411)
- Testing
- Prospective observational cohort study., A prospective observational cohort study
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Relapsed Adult AML, Primary Refractory Acute Myeloid Leukemia
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute…
- Conditions
- Relapsed Adult AML, Primary Refractory Acute Myeloid Leukemia, High Risk Acute Myeloid Leukemia
- Trial name
- SCOPE-L (NCT05237258)
- Testing
- Specialty Palliative Care, Primary Palliative Care
- Where
- 20 sites in United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital