Clinical trials: Palliative Care
Lung Disease
Evaluation of the Hospital2Home Palliative Care Service for Patients With Advanced Progressive Lung Disease
The investigators hypothesise that H2H will result in improved symptom control and quality of life and may be more cost-effective than standard best practice.
- Trial name
- H2H-ILD (NCT01450644)
- Testing
- The Hospital2Home Service
- Where
- 2 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cancer, Palliative Care
Yunzhi Essence to Improve the Quality of Life of Patients With Advanced Stage of Cancer
A randomized, double-blinded, placebo-controlled clinical trial using a Chinese Medicine 'Coriolus Versicolor for improving the quality of life of patients with advanced-stage cancer.
- Trial name
- NCT05754801
- Testing
- Yunzhi Essence
- Where
- Hong Kong
- Volunteers
- 172 people
- Sponsor
- Chinese University of Hong Kong
Any Disease Causing Death in the ICU or Within 24 Hours of Discharge From the ICU
Integrating Palliative and Critical Care (IPACC) Study
The purpose of this research study is to evaluate an intervention to improve the care given to patients who are dying in the intensive care unit (ICU) and their families.
- Trial name
- IPACC (NCT00685893)
- Testing
- Education, Local Champions, Institution Feedback
- Where
- 15 sites in United States
- Volunteers
- 3,498 people
- Sponsor
- University of Washington
Pain, Heart Failure, Congestive
Help Veterans Experience Less Pain Study (HELP-Vets)
Our purpose is to evaluate the reliability and validity of the '5th vital sign' in everyday practice settings and to compare the relationship of pain to other symptoms and pain treatment in patients with cancer, CHF, and patients…
- Conditions
- Pain, Heart Failure, Congestive, Signs and Symptoms
- Trial name
- HELP-Vets (NCT00230932)
- Where
- United States
- Volunteers
- 654 people
- Sponsor
- US Department of Veterans Affairs
Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer
EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options
The objective of this study is to improve the chemotherapy decision making process for Latinos with advanced gastrointestinal cancers.
- Conditions
- Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT03602885
- Testing
- Usual chemotherapy education (CE), Chemotherapy education intervention (CEI)
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Constipation
Effect of Abdominal Massage Training Provided to Caregivers on Constipation Management
Constipation is a common and uncomfortable problem among patients receiving palliative care. Alongside usual treatment and nursing care, abdominal massage may help manage constipation.
- Trial name
- NCT07886125
- Testing
- Caregiver Training in Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- HAMİYET KIZIL
Advanced Cancer
Cancer End Of Life Evaluation
The aim of this study is to culturally adapt and to validate Quality Of Life tools dedicated to the end of life for French cancer patients.
- Trial name
- CEOLE (NCT01545921)
- Testing
- Quality Of Life questionnaires completion
- Where
- 10 sites in France
- Volunteers
- 179 people
- Sponsor
- Institut Cancerologie de l'Ouest
Gastric Cancer, Bleeding
The Use of Proton Pump Inhibitor on the Prevention of Gastric Cancer Bleeding
The aim of this study is the effect of proton pump inhibitor (PPI) with respect to gastric cancer bleeding in inoperable patients.
- Trial name
- NCT02150447
- Testing
- Proton pump inhibitor
- Where
- 4 sites in South Korea
- Volunteers
- 394 people
- Sponsor
- National Cancer Center, Korea
Anxiety, Pain
Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children
Children undergoing leukaemia treatment are exposed to a wide range of chemotherapeutic agents and immunosuppressive therapies during treatment and are therefore at great risk for complications.
- Conditions
- Anxiety, Pain, Fear
- Trial name
- NCT06955338
- Testing
- Music intervention, Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ege University
Distal Bile Duct Obstruction
Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction
The purpose of this study is to compare the rate of long-term stent failure, defined as need for repeat biliary intervention following placement of C-SEMS vs U-SEMS for palliation of inoperable malignant distal bile duct…
- Trial name
- NCT01905384
- Testing
- Covered Self-expanding metal biliary stents (C-SEMS), Uncovered Self-expanding metal biliary stents (U-SEMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Vanderbilt University Medical Center
Older Patients, Colorectal Cancer
DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer
The goal of this phase III, open-label, non-inferiority randomized controlled clinical trial is compare upfront dose-reduced chemotherapy with the standard dose chemotherapy in older patients ( ≥70 years) with metastasized…
- Conditions
- Older Patients, Colorectal Cancer, Metastatic Cancer, Candidates for Palliative Chemotherapy
- Trial name
- DOSAGE (NCT06275958)
- Testing
- Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)
- Where
- 36 sites in Netherlands
- Volunteers
- 587 people
- Sponsor
- Leiden University Medical Center
Tourette Syndrome, Tic Disorder
Effectiveness of Symptom Management Application on Parental Care Ability of Children With Tourette Syndrome
This study developed a Tourette Syndrome (TS) symptom management application (APP) to improve the care needs, sleep quality, anxiety, quality of life, and parenting relationship of parents of children with Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tic Disorder, Neurodevelopmental Disorder
- Trial name
- NCT06613126
- Testing
- Symptom Management APP group, health education instructions group
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Palliative Care
Impact of a Gratitude-based Intervention in Palliative Care (IPBG)
This is a pilot study consisting of mixed-methods, pre-post evaluation of a gratitude intervention (gratitude letter and visit) on palliative care patients and their caregivers.
- Trial name
- IPBG (NCT03703687)
- Testing
- Gratitude intervention
- Where
- 3 sites in Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Metastatic Solid Tumor Cancers, Locally Advanced Solid Tumor Cancers
Investigating the Impact of Proactive Palliative Care
This study will test whether adding personalized supportive care to medical treatment on a clinical trial affects the study participants' ability and desire to discuss their symptoms, their concerns about the future, and their…
- Trial name
- NCT03667378
- Testing
- Expectations Survey (CanCORS), Values Survey (Serious Illness Care Program), Functional Assessment of Cancer Therapy-General (FACT-G)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Palliative Radiotherapy
LAttice Radiation Therapy for Large Lesions: Reggio Emilia Single-arm Phase II Trial
This study evaluates the activity and toxicity of Lattice Radiation Therapy (LRT) in patients with large, unresectable non-brain neoplastic lesions requiring palliative treatment.
- Trial name
- LART (NCT07000162)
- Testing
- Lattice radiation therapy
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Non-Small Cell Lung Cancer
Radiation Therapy to Relieve Symptoms in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
This study will test the safety of Quad Shot radiation therapy using 2 different treatment schedules to find out what effects, if any, this treatment has on people with advanced NSCLC who are receiving systemic therapy for their…
- Trial name
- NCT04384146
- Testing
- Cyclical Hypofractionated Palliative Radiation (Quad Shot), EORTC QLQ-C30 questionnaire
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Heart Failure
Heart to Heart Web-based Communication Program for Heart Failure
This randomized controlled trial evaluates the effectiveness of a web-based family-centered communication enhancement program ("Heart to Heart") designed for patients with heart failure, family caregivers, and cardiac nurses.
- Trial name
- NCT07479160
- Testing
- Heart to Heart Web-based Communication Program
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Heart Failure, Pulmonary Disease, Chronic Obstructive
Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD
Many Veterans living with heart failure or chronic obstructive pulmonary disease (COPD) experience significant symptoms - such as breathlessness, fatigue, depression, and anxiety -that reduce their quality of life.
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Interstitial Lung Disease
- Trial name
- VITALVET:ADAPT (NCT07714252)
- Testing
- Virtual Nurse and Social Worker Palliative Care Team, Enhanced Implementation Support, Standard Implementation Support
- Where
- 7 sites in United States
- Volunteers
- 420 people
- Sponsor
- VA Office of Research and Development
Palliative Care, Dyspnea
The Effect of Acupressure on the Management of Dyspnea
Dyspnea can develop at any stage of the disease, but it is more common in the last period of life. Complementary and integrative methods used for dyspnea symptoms include acupuncture, acupressure, visualization techniques, herbal…
- Trial name
- NCT05884450
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Cholangiocarcinoma
the Impact of Early Palliative Care on the Survival of Locally Advanced and / or Metastatic Cholangiocarcinoma Patients
The prognosis for cholangiocarcinoma is bad. Potentially, early management by a palliative care team could increase overall survival.
- Trial name
- NCT04415190
- Testing
- early palliative care
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
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