Clinical trials: Palate; Wound
Cleft Lip, Cleft Palate +/- Lip
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children.
- Conditions
- Cleft Lip, Cleft Palate +/- Lip, Pain Management, Wound Dehiscence, Surgical
- Trial name
- NCT07892963
- Testing
- Palatal Nerve Block, Suprazygomatic Maxillary Nerve Block
- Volunteers
- 144 people
- Sponsor
- Children's National Research Institute
Gingival Recession, Generalized, Gingival Recession, Localized
Clinical and Histological Evaluation of Subepithelial Connective Tissue Graft Maturation at Different Healing Timepoints, With and Without Topical Application of a Polynucleotide- and Hyaluronic Acid-Based Gel
This study evaluates whether a 9-week healing interval is sufficient for subepithelial connective tissue graft (SCTG) maturation after palatal harvesting, and whether topical application of a polynucleotide and hyaluronic acid…
- Conditions
- Gingival Recession, Generalized, Gingival Recession, Localized, Wound Healing, Palate; Wound
- Trial name
- NCT07708051
- Testing
- polynucleotide and hyaluronic acid gel, subepithelial connective tissue graft harvesting
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Palate; Wound
Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting
Clinical Comparison of Albumin Platelet Rich- Fibrin (Alb- PRF) versus Platelet-rich fibrin (PRF) on Postoperative Morbidity Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial(RCT) Study settings…
- Trial name
- NCT06567548
- Testing
- control group, Platelet-rich fibrin (PRF), Albumin Platelet Rich- Fibrin
- Where
- 3 sites in Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Palate; Wound
Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing
The goal of this clinical trial is to learn if the use of cyanoacrylate glue (PeriAcryl) is effective in healing of the palatal donor site in adults requiring a free gingival graft.
- Trial name
- RCT (NCT07086482)
- Testing
- Cyanoacrylate tissue adhesive, Collagen sponge
- Where
- Lebanon
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Pain, Postoperative, Palate; Wound
Use of Tilapia Skin for Palate Repair and Protection After Graft Removal
Randomised Clinical Study to evaluate the efficacy of tilapia skin as an occlusive biological dressing on palatal wound healing after free gingival graft harvesting.
- Conditions
- Pain, Postoperative, Palate; Wound, Cicatrization
- Trial name
- NCT04168125
- Testing
- Tilapia skin, Surgical Wound Dressing
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Wound Healing, Palate; Wound
Palatal Mucosa Wound Healing Following Antimicrobial Gel Application
The present study will be a prospective, randomized, triple-blind, split-mouth, clinical trial. The study timeline will be include seven total visits.
- Conditions
- Wound Healing, Palate; Wound, Hyaluronic Acid
- Trial name
- BIOR_01 (NCT06737653)
- Testing
- Gel containing postbiotics, lactoferrin, aloe barbadensis leaf juice powder and sodium hyaluronate
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- University of Roma La Sapienza
Palate; Wound
Palatal Donor Site Wound Healing Following Periodontal Plastic Surgery Using Amnion-Chorion Membrane
The purpose of this clinical trial is to assess if donor site healing in the palatal area and patient pain perception are similar or different when using amnio-chorion membrane (ACM) on the donor site after surgery compared to a…
- Trial name
- NCT05927714
- Testing
- Amnion-chorion Membrane, ActCel Cellulose Gauze
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Wound Healing Disorder, Palate; Wound
Evaluation of the Effect of Hypericum Perforatum L and Hyaluronic Acid on Excisional Palatal Wound Healing
The free gingival graft (FGG) procedure is one of the surgical approaches used to create a large area of adherent gingiva around the tooth and implant.
- Trial name
- NCT06543199
- Testing
- local application of hyaluronic acid agent to the wound site, Local application of hypericum perforatum L to the wound site, wound healing monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ataturk University
Gingival Recession, Palate; Wound
To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting
This randomized clinical comparative study will evaluate the postoperative pain following the FGG graft harvest procedure technique covered by four different methods for coverage of the palatal donor site.
- Trial name
- NCT03895476
- Testing
- palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Palate; Wound, Wound Heal
Comparison of Palatal Wound Healing in Diabetic and Non-diabetic Patients
This study aims to characterize and compare the closure of open wounds in the palatal mucosa of diabetic and non-diabetic patients, evaluate clinical, patient-centered and immunological parameters as well as wound microbiome…
- Conditions
- Palate; Wound, Wound Heal, Diabetes
- Trial name
- NCT06540690
- Testing
- Palatal Wound
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Pain, Postoperative, Quality of Life
To Evaluate Postoperative Pain and Quality of Life After Taking a Deephethelized Gingival Graft and Covering it With Different Treatments
Objective: To evaluate postoperative pain and quality of life in relation to oral health after obtaining a palatal de-epithelialized gingival graft and subsequent coverage of the surgical wound with an adhesive film of cellulose…
- Conditions
- Pain, Postoperative, Quality of Life, Palate; Wound
- Trial name
- NCT06408792
- Testing
- Deepithelized graft and protection technique
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Palate; Wound
Palate Wound Healing and Pain Perception of De-epthelized Ctg vs Sub-epithelial Ctg
A single blinded randomized clinical trial was designed to evaluate the influence of palatal harvesting technique on post-operatory patient pain perception.
- Trial name
- NCT05828394
- Testing
- DFGG, SCTG
- Where
- 2 sites in Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Palate; Wound
L-PRF Versus A-PRF on Palatal Wound Healing
Different approaches are used to reduce post-operative complications associated with the palatal wound site after free gingival graft (FGG) harvesting.
- Trial name
- NCT06242314
- Testing
- L_PRF, A-PRF, Palatal stent
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Gingival Recession, Palate; Wound
Ultrasonographic Assessment of Palatal Wound Healing
Palatal-tissue harvesting is a routinely performed procedure in periodontal plastic surgery. Subepithelial connective tissue graft (sCTG) is considered the gold standard in root coverage.
- Trial name
- NCT06118177
- Testing
- connective tissue harvesting, ultrasonography, autolog platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Palate; Wound
Laser Bandage and Surgical Stent as Palatal Donor Site Dressing After Free Gingival Graft Surgery.
The free gingival graft (FGG) procedure is a harvesting technique that creates an open wound that heals by secondary intention. Retarded wound healing, excessive bleeding, and postoperative pain have been reported after FGG…
- Trial name
- NCT05841641
- Testing
- Laser Bandage, Hemostatic agent with surgical stent
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Palate; Wound
Clinical Comparison of Application of Curcumin Gel in Pain Management After Free Gingival Graft Harvesting
The aim of this study is to compare the effect of using 2% curcumin gel versus gelatin sponge when applied to palatal donor site in pain management and wound healing after free gingival graft harvesting.
- Trial name
- curcumin (NCT05819632)
- Testing
- curcumin gel 2%
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Open Wound of Palate Without Complication, Pain, Postoperative
The Effect of Ozone Therapy on Pain Perception After Free Gingival Graft Surgery in Patients With Mucogingival Defects
Gaseous ozone (O3-triatomic oxygen) is the third-strongest oxidizing agent worldwide. It influences the cellular and the humoral immune system, by stimulating the proliferation of immunocompetent cells and the synthesis of…
- Conditions
- Open Wound of Palate Without Complication, Pain, Postoperative, Free Gingival Grafts, Mucogingival Defects
- Trial name
- NCT05291715
- Testing
- Ozone generator device (Ozone DTA-APOZAa-enterprize CO9-Taiwan, R.0.C)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Omaima Mossad Mahmoud AL-Sherbini
Palate; Wound
Evaluation of the Use of Ozone Gel Versus Hyaluronic Acid Gel on Palatal Wound Healing .
To compare the effect of Ozone Gel versus Hyaluronic acid gel 0.2% applied to palatal donor site in post-operative pain reduction after free gingival graft harvesting.
- Trial name
- NCT05690100
- Testing
- GeliO3, Gingi gel
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Healing, Palate; Wound
Manufacturing, Characterization and Evaluation of the Effect of Silk Fibroin Membranes, Loaded or Not With Neurotensins on Open Wounds in the Palate
The aim of the present study will be to manufacture and characterize silk fibroin membranes loaded or not with neurotensin and to evaluate clinical, patient-centered and immunological parameters the effect of using these…
- Trial name
- NCT05191082
- Testing
- Palatal Wound, Palatal Wound treated with Silk Fibroin Film, Palatal Wound treated with Neurotensin-loaded Silk Fibroin Film
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Wound Healing, Insulin
A New Drug Delivery System - Silk Fibroin Film Loaded or Not With Insulin on Palatal Mucosa Wound Healing
The aim of the present study is to evaluate using clinical, patient-centered, immunological, microbiological, and histological parameters, the effect of silk fibroin films loaded or not with insulin in the repair of palatal…
- Conditions
- Wound Healing, Insulin, Palate; Wound
- Trial name
- NCT05171400
- Testing
- Palatal Wound, Palatal Wound treated with Silk Fibroin Film, Palatal Wound treated with Insulin-loaded Silk Fibroin Film
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho