Clinical trials: Pain Management After Abdominal Surgery
Postoperative Pain, Midline Laparotomy
Efficacy of Adding Intrathecal Morphine to Erector Spinae Plane Block for Postoperative Analgesia After Midline Laparotomy
This study evaluates whether combining two distinct pain-relief techniques-a peripheral nerve block called the Erector Spinae Plane Block (ESPB) and a low-dose spinal medication injection called Intrathecal Morphine…
- Trial name
- NCT07720739
- Testing
- Intrathecal Morphine, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Sohag University
Inguinal Hernia
Postoperative Analgesia After Low Frequency Electroacupuncture
The purpose of this study is to determine whether electroacupuncture is a effective tool to the postoperative analgesia
- Trial name
- LFE (NCT01722253)
- Testing
- Electroacupuncture
- Where
- Greece
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Postoperative Pain, Inflammatory Response
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
- Trial name
- NCT03958942
- Testing
- Ultrasound quadratus lumborum block with bupivacaine 25%, lumbar epideural block with bupivacaine 25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Abdominal Wall Hernia, Pancreatic Diseases
IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Number of patients with unsatisfactory pain relief defined as average visual analog scale (VAS) more than 5 with or without requirement of IVPCA for pain relief during the first 48 hours postoperative period will be compared…
- Conditions
- Abdominal Wall Hernia, Pancreatic Diseases, Bowel Disease, Gastric Disease
- Trial name
- NCT03198871
- Testing
- Acetaminophen Injectable Product, Sodium Chloride 0.9%, Intravenous
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kathirvel Subramaniam
Lower Abdominal Surgery
Transversus Abdominis Plane Versus Caudal Block for Pediatrics
The transversus abdominis plane (TAP) block is a relatively simple technique that provides myocutaneous anesthesia that, as part of a multimodal analgesic treatment, may be useful in the prevention and treatment of parietal…
- Trial name
- NCT02398123
- Testing
- Transversus abdominis plane block, Caudal block, Bupivacaine
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Mansoura University
Laparoscopic Cholecystectomy Surgery, Analgeisa
Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration
Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain…
- Conditions
- Laparoscopic Cholecystectomy Surgery, Analgeisa, Local Anesthetic Infiltration
- Trial name
- NCT07409688
- Testing
- Intraoperitoneal local anesthetic administration, Sub cutaneous administration of local anesthetic
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Analgesia
Study of Post-Herniorrhaphy Non-opioid MMA Regimens
This is a Phase 3b, open-label study to assess postoperative opioid use in subjects undergoing unilateral open inguinal herniorrhaphy with intraoperative administration of HTX-011 and a postoperative non-opioid multimodal…
- Trial name
- NCT03907176
- Testing
- HTX-011, Luer lock applicator, Ibuprofen
- Where
- 30 sites in United States
- Volunteers
- 209 people
- Sponsor
- Heron Therapeutics
Opioid Use, Auriculotherapy
Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement
The NSS-2 BRIDGE® device (NSS stands for Neuro-Stimulation System) is a disposable device that stimulates the branches of cranial nerves and of the superficial cervical plexus innervating the ear.
- Conditions
- Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain
- Trial name
- NCT05506878
- Testing
- NSS-2 BRIDGE
- Where
- 4 sites in United States
- Volunteers
- 286 people
- Sponsor
- Jacques E. Chelly
Postoperative Pain
The Goal of This Study is to Evaluate the Effect of Ultrasound Guided Erector Spinae Plane Block on Postoperative Pain After Major Abdominal Surgeries
Aim of the work To evaluate the efficacy of ultrasound-guided erector spinae plane block for management of postoperative pain in patients undergoing major abdominal surgery under general anesthesia.
- Trial name
- NCT04382209
- Testing
- Erector spinae plane block, Intravenous meperidine patient controlled analgesia device
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Suez Canal University
Pain, Postoperative
Acetaminophen vs Placebo for Postoperative Analgesia After Abdominal Surgery
This study investigates whether oral acetaminophen, when added to standard pain management, reduces opioid use and pain after major abdominal surgery, compared to a placebo (inactive pill).
- Trial name
- NCT07720791
- Testing
- Acetaminophen
- Volunteers
- 1,504 people
- Sponsor
- Konya City Hospital
Inguinal Hernia
PRO-RSTAP: Effect of TAP and RS Blocks on Recovery After Inguinal Hernia Surgery (PRO-RSTAP)
Inguinal hernia repair is a common surgical procedure, often performed as day-case surgery. Despite standardized surgical techniques, postoperative pain may delay recovery and occasionally lead to unplanned hospital admission.
- Trial name
- PRO-RSTAP (NCT07423910)
- Testing
- Transversus abdominis plane block (TAP block), Rectus sheath block (active), Ropivacaine
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Post-Operative Pain
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
The study is intended to show that the Sufentanil NanoTab PCA System is as effective as morphine intravenous patient-controlled analgesia (IV PCA) for treating pain after surgery.
- Trial name
- NCT01539538
- Testing
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Where
- 16 sites in United States
- Volunteers
- 357 people
- Sponsor
- Talphera, Inc
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Postoperative Pain
Patient-Controlled Epidural Analgesia (PCEA) for Patients Who Have Had Major Open Gynecologic Surgery
Recovery after major abdominal surgery can be longer than other types of surgery. This is because often after abdominal surgery, the bowel does not work normally. When this happens, patients are unable to pass gas.
- Trial name
- NCT00136682
- Testing
- patient-controlled epidural analgesia (PCEA), patient-controlled intravenous analgesia (PCA)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Participants With Acute Moderate to Severe Pain Following Abdominal Surgery
Efficacy and Safety of Intravenous Meloxicam in Subjects With Moderate-to-severe Pain Following Abdominal Surgery
This study aims to evaluate the analgesic efficacy and safety of meloxicam injection in subjects with moderate-to-severe pain following abdominal surgery.
- Trial name
- NCT06904248
- Testing
- Meloxicam Injection, Sodium Chloride Injection
- Where
- 18 sites in China
- Volunteers
- 224 people
- Sponsor
- Yangtze River Pharmaceutical Group Co., Ltd.
Abdominal Neoplasms
Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia in Cancer Surgery
the investigators aim is to investigate the effect of continuous preperitoneal bupivacaine wound infiltration versus epidural analgesia on the inflammatory cytokines response following radical cytectomy
- Trial name
- NCT03002909
- Testing
- epidural catheter, preperitoneal catheter
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
QLB in Lower Abdominal Cancer Surgeries as a Post Operative Analgesia
Role of Magnesium Sulphate as an Adjuvant to Bupivacaine in U.S Guided Quadratus Lumborum Block in Lower Abdominal Cancer Surgeries
The aim of this study is to assess the efficacy of Mg sulfate ( 10% ) as an adjuvant to Bupivacain ( 0.25 % ) in an U.S guided QLB for postoperative analgesia and postoperative Morphine consumption in lower abdominal cancer…
- Trial name
- NCT06301789
- Testing
- Effect of adding Mg sulfate as an adjuvant to bupivacain in U/S guided QLB for postoperative analgesia in lower abdominal cancer surgeries
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post Operative Analgesia
Bilateral External Oblique Intercostal Plane Bock (EOIPB) in Upper Abdominal Surgeries
The current study is designed to investigate the analgesic potentials of two modalities of abdominal blocks where local anesthetics is injected in the fascial planes of the abdominal muscles to anesthetize the nerves supplying…
- Trial name
- NCT07055438
- Testing
- Ultrasound guided Rectus sheath block, ultrasound guided external oblique intercostal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Post Operative Analgesia, Dexmedetomidine
Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone
Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding…
- Conditions
- Post Operative Analgesia, Dexmedetomidine, TAP Block
- Trial name
- NCT07508202
- Testing
- Dexmedetomidine, Dexamethasone
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences