Clinical trials: Pain Management After Abdominal Surgery
Post-Operative Pain
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
The study is intended to show that the Sufentanil NanoTab PCA System is as effective as morphine intravenous patient-controlled analgesia (IV PCA) for treating pain after surgery.
- Trial name
- NCT01539538
- Testing
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Where
- 16 sites in United States
- Volunteers
- 357 people
- Sponsor
- Talphera, Inc
Abdominal Cancer
Comparsion Between Intravenous Infusion of Ketofol and Inhalational Anasthetics in Abdominal Cancer Surgeries for Post Operative Analgesia
( post operative pain between intravenous infusion ketofol and standard inhalational general anesthesia in abdominal cancer surgeries )
- Trial name
- NCT06265948
- Volunteers
- 80 people
- Sponsor
- Assiut University
Post Operative Pain, Quadratus Lumborum Block
Pediatric Postoperative Analgesia With Quadratus Lumborum Block(QLB) And Dexamethasone As An Adjuvant To Bupivacaine.
Studying the post-operative analgesic effect of dexamethasone as an adjuvant to bupivacaine giving intravenously and locally with ultrasound guided quadratus lumborum block(QLB) in pediatrics undergoing abdominal surgeries
- Conditions
- Post Operative Pain, Quadratus Lumborum Block, Pediatric, Abdominal Surgery
- Trial name
- QLB (NCT04963816)
- Testing
- ultrasound guided quadratus lumborum block, Dexamethasone Phosphate 4 MG/ML Injectable Solution intravenously, Bupivacaine Injection
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Analgesia
Intraperitoneal Tramadol Versus Dexmedetomedine for Analgesia After Abdominal Laparoscopic Cancer Surgeries
Multiple modalities for postoperative analgesia after laparoscopic procedures has been used, of them intraperitoneal route (IP) was used to decrease the analgesic requirements.
- Trial name
- NCT04813016
- Testing
- Tramal 1, Tramal 2, Dexmedetomidine 1
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute, Egypt
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Child
Surgical Transversus Abdominis Plane Block in Pediatric Patients
The objective of this study to determine the effect of surgical transversus abdominis plane block and local infiltration for postoperative pain control in major abdominal surgery compare with control group.
- Trial name
- TAP (NCT01548027)
- Testing
- Local infiltration group, TAP block, No intervention
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Postoperative Pain
Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery
Pain following abdominal surgery is managed with the use of thoracic epidural analgesia (TEA) where the epidural is inserted in the spine at the level of scapula The risks due to TEA include difficulty with insertion, failure in…
- Trial name
- NCT01735851
- Testing
- Thoracic epidural analgesia, Bilateral Paravertebral block
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Inguinal Hernia
M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Inguinal hernia repair is the most common of abdominal surgical procedures and is usually performed laparoscopically. Many factors play a role in the pain that develops after surgery and is generally considered to be visceral…
- Trial name
- NCT05476510
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Laparoscopic Abdominal Surgery
Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery
This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery.
- Trial name
- NCT06772545
- Testing
- Epidural Analgesia, Paravertebral Block, Transversus Abdominis Plane Block
- Volunteers
- 120 people
- Sponsor
- Xiaguang Duan
Rescue Analgesia
Comparison of Rescue Analgesia Requirement in Patients Undergoing Laparoscopic Cholecystectomy After Transversus Abdominal Plane (tap) Block Vs Local Anesthetic Wound Infiltration At the End of Surgery
patients undergoing laparoscopic cholecystectomy will be diveided into 2 groups A \& B . Group A will receive local anesthetic wound infiltration and group B will receive Transversus abdominal plane block as a post operative…
- Trial name
- TAP (NCT06803966)
- Testing
- Post Operative Analgesia
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Postoperative Pain, Inflammatory Response
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
- Trial name
- NCT03958942
- Testing
- Ultrasound quadratus lumborum block with bupivacaine 25%, lumbar epideural block with bupivacaine 25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain
Transversus Abdominis Plane Block Versus Local Anesthetic Infiltration for Pain Control in the Abdominal Surgery
Postoperative analgesia is an important part of the anesthetic care. According to the recent studies, multimodal analgesia can provide better analgesia \& patient satisfaction with fewer side effect.
- Trial name
- TAP (NCT02029755)
- Testing
- transversus abdominis plane block, local infiltration, Patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- Taipei Medical University Hospital
Abdominal Muscles/Ultrasonography, Adult
Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair
Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage
- Trial name
- NCT01589796
- Testing
- TAP block
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stamford Anesthesiology Services, PC
Oxycodone, Chronic Pain, Postoperative
Effect of Preventive Analgesia with Oxycodone and Parecoxib Sodium on the Chronification of Acute Post-operative Pain
The goal of this clinical trial is to learn if the administration of oxycodone for preventive analgesia works to reduce the chronification of acute postoperative pain in adult participants undergoing major abdominal surgery.
- Trial name
- AOPC (NCT06721988)
- Testing
- oxycodone and parecoxib sodium combinations
- Volunteers
- 1,316 people
- Sponsor
- Ailin Luo
Block
Retrolaminar Block Versus Tab Block in Abdomioasty
The aim of the study is to compare the analgesic efficacy of Us guided retrolaminar block versus transversus abdominis plane block in patient under going abdominal plastic surgery
- Trial name
- NCT06265402
- Testing
- Tab block versus retrolaminar block in abdominal plastic surgery
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain After Surgery
RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial
The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal…
- Trial name
- NCT07593300
- Testing
- Group A (n=35): Ultrasound-guided RISS block (RISS):, Group B (n=35): Ultrasound-guided lower thoracic ESP block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Undergoing Hysterectomy
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing hysterectomy on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993226
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 115 people
- Sponsor
- Durect
Postoperative Pain
Postoperative Pain Relief After Major Abdominal Gynecological Surgery
The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue…
- Trial name
- NCT05845385
- Testing
- lumbar epidural analgesia with bupivacaine, transversus abdominis plane block with bupivacaine, wound infiltration with bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cukurova University