Clinical trials: PMDD
Premenstrual Dysphoric Disorder (PMDD)
Occupational Physicians Facing Premenstrual Dysphoric Disorder: Knowledge, Perceptions and Practices in Occupational Health
This study aims to assess the knowledge, perceptions and practices of occupational physicians regarding premenstrual dysphoric disorder (PMDD), a condition with significant occupational impact that remains insufficiently explored…
- Trial name
- TDPM (NCT07864285)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Menstruation Disturbances, Premenstrual Syndrome
Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder
The purpose of this study is to determine whether levonorgestrel (LNG)/ethinyl estradiol (EE) is effective in treating the symptoms of severe premenstrual syndrome (PMS).
- Trial name
- NCT00128934
- Testing
- levonorgestrel/ethinyl estradiol
- Where
- 83 sites in United States, Canada
- Volunteers
- 744 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
PMS
Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study
The purpose of this pilot study is to determine the efficacy and safety of escitalopram administered premenstrually (day 14 through day 2 of the menstrual cycle) for severe PMS in young women ages 15-19 years.
- Trial name
- NCT00523705
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pennsylvania
Premenstrual Dysphoric Disorder
A Study of Efficacy and Safety of Sepranolone (UC1010) in Patients With Premenstrual Dysphoric Disorder (PMDD)
The objective of this phase IIb study is to evaluate the effect and safety of Sepranolone (UC1010) on premenstrual symptoms in women with Premenstrual Dysphoric Disorder (PMDD).
- Trial name
- NCT03697265
- Testing
- Sepranolone (UC1010) low dose, Sepranolone (UC1010) high dose
- Where
- 12 sites in Germany, Poland and 2 more
- Volunteers
- 475 people
- Sponsor
- Asarina Pharma
Premenstrual Disorder
The Effect of Progressive Muscle Relaxation Exercises on Premenstrual Syndrome, Anxiety, and Tendency to Violence in Young Women
This study results will provide evidence on the effectiveness of Progressive Muscle Relaxation Exercises (PMRE) as a complementary method in improving Premenstrual Syndrome (PMS), an important women's health issue.
- Trial name
- NCT06909955
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Premenstrual Dysphoric Disorder
Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder
The objective of this study is to evaluate the effectiveness and safety in double-blind, randomized, placebo-controlled clinical trials of self administered PH80 intranasal spray for the acute management of cycle related symptoms…
- Trial name
- PH80-PMD (NCT01217775)
- Testing
- PH80
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Premenstrual Syndrome, PMS
Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives
This study will determine whether uninterrupted treatment with birth control pills over several menstrual cycles prevents severe premenstrual syndrome (PMDD).
- Conditions
- Premenstrual Syndrome, PMS, Premenstrual Dysphoric Disorder, PMDD
- Trial name
- NCT00089414
- Testing
- Ethinyl Estradiol/Drospirenone, CDB 2914
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy, Premenstrual Dysphoric Disorder
The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms
The purpose of this study is to assess Mixhers HERTIME supplements efficacy in alleviating menstrual cycle symptoms.
- Conditions
- Healthy, Premenstrual Dysphoric Disorder, Premenstrual Syndrome
- Trial name
- NCT06136104
- Testing
- Mixhers HERTIME
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Midwestern University
PMDD, Stress
Stress & Premenstrual Symptoms Study
This study that aims to evaluate the psychophysiology of premenstrual mood disorders (PMDs) at baseline and after treatment with sertraline. Participants will include women with PMDs and healthy female controls.
- Conditions
- PMDD, Stress, Mood
- Trial name
- NCT02777372
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders
The purpose of this study is to assess a novel nutritional supplement developed for prenatal health and mood benefits, and to determine whether there is preliminary evidence for efficacy in Menstrual Related Mood Disorders…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Premenstrual Tension, Menstrual Related Mood Disorder
- Trial name
- NCT04123483
- Testing
- EnBrace HR Softgel
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Premenstrual Dysphoric Disorder
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age.
- Trial name
- Premensis-s (NCT06496139)
- Testing
- Therapist-guided internet-delivered cognitive behavioural therapy
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Uppsala University
PMDD, Premenstrual Dysphoric Disorder (PMDD)
Identification and Validation of Epigenetic Biomarkers of PMDD
This research is being done to examine epigenetic markers and mood changes across the menstrual cycle, particularly in premenstrual dysphoric disorder (PMDD).
- Conditions
- PMDD, Premenstrual Dysphoric Disorder (PMDD), Premenstrual Syndrome-PMS, Premenstrual Syndrome
- Trial name
- BIO (NCT06771583)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Premenstrual Dysphoric Disorder ( PMDD), PMDD
MLS101 Study in PMDD
The goal of this clinical trial is to learn if MLS101 (psilocybin) is a possible treatment for women with Premenstrual Dysphoric Disorder (PMDD).
- Trial name
- NCT07818720
- Testing
- MLS101 psilocybin
- Volunteers
- 32 people
- Sponsor
- MycoMedica Life Sciences PBC
Premenstrual Dysphoric Disorder, Bipolar Disorder
Oral Contraceptives for Treating Premenstrual Dysphoric Disorder in Bipolar Disorder
This study is a pilot, randomized, placebo-controlled trial evaluating the treatment of Premenstrual Dysphoric Disorder comorbid with Bipolar Disorder using combined oral contraceptives.
- Trial name
- NCT05098574
- Testing
- Yaz
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Epilepsy
Premenstrual Dysphoric Disorder and Antiepileptic Drugs
This study is being done to determine if there are differences in mood during the menstrual cycle among women with epilepsy who take various different antiepileptic drugs and women without epilepsy.
- Trial name
- NCT00612235
- Testing
- Lamotrigine, Levetiracetam, Carbamazepine
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Premenstrual Dysphoric Disorder, Premenstrual Syndrome
A Placebo-Controlled Study to Investigate the Onset of Action of Paroxetine in Premenstrual Dysphoria
The objective of this study is to explore the onset of action when serotonin reuptake inhibitors are used to treat premenstrual dysphoric disorder
- Trial name
- NCT00516113
- Testing
- paroxetine
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska Institutet
Premenstrual Dysphoric Disorder
Premenstrual Hormonal and Affective State Evaluation (PHASE) Project
PHASE is designed to evaluate neuroactive hormone trajectories across the menstrual cycle and endocrine, autonomic, and subjective responses to psychosocial stress in women suffering from severe PMS (i.e., premenstrual dysphoric…
- Trial name
- PHASE Project (NCT03862469)
- Testing
- Individualized laboratory test
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Premenstrual Dysphoric Disorder
Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study
This research study will look at brain and symptom differences among women with severe premenstrual mood symptoms. One goal of this study is to look at the effects of taking a nasal spray containing oxytocin (a hormone made in…
- Trial name
- NCT02508103
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Premenstrual Dysphoric Disorder (PMDD)
Neurofeedback Treatment of Affective Instability in Premenstrual Dysphoric Disorder(PMDD)
Premenstrual Dysphoric Disorder (PMDD) is characterized by affective instability and irritability, diagnosed in 5% of reproductive-age women.
- Trial name
- NCT01945372
- Testing
- EEG NeuroFeedback
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Premenstrual Dysphoric Disorder ( PMDD)
To Establish Whether Individuals With Premenstrual Dysphoric Disorder (PMDD) Demonstrate a Different Luteal-phase Sex Hormone Profile and Ratio Compared With Asymptomatic Controls.
The aim of this project is to compare the ovarian hormone levels 7 days after ovulation and progesterone:oestradiol ratios between PMDD individuals and a control cohort (case control study).
- Trial name
- NCT07686718
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lancaster University