Clinical trials: Oxygen Reserve Index
Hyperoxia
Assessment of Oxygenation With Oxygen Reserve Index for General Anesthesia
To assess oxygenation with the oxygen reserve index in desflurane anesthesia administration using low and high fresh gas flows for tympanomastoidectomy surgeries.
- Trial name
- NCT04698863
- Testing
- Oxygen reserve index
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Intensive Care Units
ORI2 : ORI for hyperOxia Reduction in ICU
Recently, hyperoxia has been recognized as being potentially deleterious for critically ill patients, with increased duration of mechanical ventilation and even with increased mortality rates.
- Trial name
- ORI2 (NCT02878460)
- Testing
- monitoring with ORI + SpO2, monitoring with SpO2
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Hyperoxemia
A Titration of Fractional Inspired Oxygen Using Oxygen Reserve Index in Child
The purpose of this prospective randomized controlled trial is to determine whether using the Oxygen Reserve Index can prevent hyperoxemia in pediatric patients receiving single-lung ventilation.
- Trial name
- NCT05912543
- Testing
- Titration of FiO2
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Airway Obstruction, Obstructive Sleep Apnea
Relationship Between STOP BANG Score and Airway Management
Nowadays, anesthetists may encounter many patients who are not diagnosed with obstructive sleep apnea syndrome (OSAS) to undergo elective surgery.
- Conditions
- Airway Obstruction, Obstructive Sleep Apnea, Hypoxia
- Trial name
- NCT05640856
- Testing
- intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Children, Congenital Heart Surgery
The Relationship Between Oxygen Reserve Index and PaO2
Oxygen Reserve Index (ORI) is a new parameter for noninvasive monitoring of oxygen reserve using oximetry sensor. In this study, the investigators evaluate the correlation between ORI and the partial pressure of arterial blood…
- Trial name
- NCT03130023
- Testing
- Pulse Oximeter with ORI
- Where
- South Korea
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Atelectasis, Lung Ultrasonography Score
Can Atelectasis Be Prevented With Oxygen Reserve Index (ORI) Monitoring?
This single-center randomized controlled trial aims to evaluate whether intraoperative monitoring using the Oxygen Reserve Index (ORI) reduces the incidence of postoperative atelectasis, as assessed by lung ultrasound (LUS), in…
- Conditions
- Atelectasis, Lung Ultrasonography Score, Hyperoxia
- Trial name
- NCT07050719
- Testing
- Peripheral Oxygen Saturation (SpO₂) Group, Peripheral Oxygen Saturation and Oxygen Reserve Index (SpO₂-ORI) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Antalya Training and Research Hospital
Oxygen Deficiency
Comparison of Oxygen Reserve Index and Regional Cerebral Oxygen Saturation Indetermining Hypoxia in Obese Patients
The primary aim of this study is to compare the effectiveness of ORI and rcSO2 in predicting hypoxia early in obese patients who are sensitive to hypoxia.
- Trial name
- NCT06404151
- Testing
- monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Hyperoxemia
Oxygen Reserve Index to Reduce Hyperoxia
Excessive oxygen administration is known to cause oxidative stress, and absorption atelectasis. Hyperoxia is very common in general anesthesia settings.
- Trial name
- NCT04211246
- Testing
- Titration of fraction of inspired oxygen (FiO2) guided by SpO2, Titration of fraction of inspired oxygen (FiO2) guided by ORI and SpO2
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Eunah Cho, MD
HYPEROXY, OXYGEN RESERVE INDEX
ORI MONITORING IN LOW AND NORMAL FLOW ANESTHESIA APPLICATIONS
Oxygen administration is essential in the perioperative period to prevent hypoxia; however, excessive oxygen may cause hyperoxia and related complications.
- Trial name
- NCT07538817
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia
Comparison of the Efficacy of High-flow Nasal Oxygen Therapy and Facial Mask Ventilation on the Increase of the Oxygen Reserve Index During Anesthetic Induction
The purpose of this study is to compare the ability of oxygenation with high-flow nasal oxygen therapy and mask ventilation technique for induction of anesthesia in adult patients who are planning to undergo surgery under general…
- Trial name
- NCT04291339
- Testing
- High-flow nasal oxygen technique, Mask ventilation technique
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Yonsei University
Desaturation of Blood, Anesthesia
Early Warning for Desaturation by Oxygen Reserve Index
During the induction of general anesthesia, the anesthesiologist needs to provide the oxygen supply to meet the patient's needs continuously.
- Trial name
- NCT04976504
- Testing
- Oxygen reserve index
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
General Anesthetic
Comparison of the Effects of High, Low and Minimal Flow Anesthesia Managements on ORI and Partial Oxygen Pressure
The aim of our study is to show that continuous oxygen reserve index monitoring is a non-invasive monitoring method that can be used as a supporting parameter to PaO2 in blood gas in hypoxia and hyperoxia monitoring when…
- Trial name
- NCT05329233
- Testing
- Masimo Radical-7 Pulse CO-Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Samsun Education and Research Hospital
Intubation, Mechanical Ventilation
Validation of the Relationship Between Oxygenation Parameters and ORI™, in Mechanically Ventilated ICU Patients
The ORI™ or Oxygen Reserve Index (Masimo, Irvine, CA, USA) is a non-invasive monitoring system for measuring oxygen reserve. It is a digital sensor (almost identical to the SpO2 sensor) which allows an analysis of the absorption…
- Conditions
- Intubation, Mechanical Ventilation, Intensive Care Unit
- Trial name
- FiO2RI (NCT05085119)
- Testing
- Stepwise modifications of FiO2
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
Oxygen Reserve Index (ORi) Expanded Data Set Validation of INVSENSOR00029
ORi is a unitless index that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT04079842
- Testing
- INVSENSOR00029
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Healthy
Comparison of Preoxygenation Techniques in Healthy Volunteers With Monitoring of End-tidal Oxygen Fraction (FeO₂) and Oxygen Reserve Index (ORI)
The objective of this physiological study is to compare two preoxygenation techniques (non-invasive ventilation combined with high-flow nasal oxygen versus non-invasive ventilation alone) by monitoring end-tidal oxygen fraction…
- Trial name
- OXYGAME1 (NCT07334041)
- Testing
- Preoxygenation with VNI + OHD, Preoxygenation with VNI
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Deep Sedation
Airway Management During Deep Sedation in Hysteroscopy
Hysteroscopy is used to examine and treat uterine diseases. Because of severe pain due to uterine distention and cervical dilatation, deep sedation usually be provided during this procedure.
- Trial name
- NCT05701839
- Testing
- face mask ventilation, nasopharyngeal tube ventilation, oxygen saturation monitoring
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Hypoxia, Hyperoxia
Different Preoxygenation Methods In Cesarean Section
The study aimed to evaluate different preoxygenation methods (tidal volume for 3 minutes and 4 deep breaths) in pregnant women with oxygen reserve index (ORI).
- Trial name
- NCT05395975
- Testing
- Oxygen Reserve Index
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Hypoxemia, Procedural Sedation
The Effectivity of End-tidal CO2 and Oxygen Reserve Index (ORI) Monitoring in Sedation
Endoscopic procedures are commonly performed using sedation. As drug-induced respiratory depression is a major cause of sedation-related morbidity, pulse oximetry has been established as standart practice .
- Conditions
- Hypoxemia, Procedural Sedation, Hypercapnia, Apnea
- Trial name
- NCT04793178
- Testing
- Oxygen Reserve Index, Masimo Corporation, USA.
- Volunteers
- 200 people
- Sponsor
- Yuksek Ihtisas Hospital
Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity
ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest
The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic…
- Trial name
- ORI-ONE (NCT03653325)
- Testing
- ORI measurement, oxygen saturation measurement
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Hyperoxia, Delirium in Old Age
The Effect of Intraoperative Hyperoxemia on Postoperative Delirium in Geriatric Patients
Oxygen therapy is the most common treatment modality for patients with hypoxemia, but target values for normoxemia are not clearly defined. Therefore, iatrogenic hyperoxemia is a very common situation.
- Trial name
- NCT06326372
- Testing
- control, ORi+SpO2
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital